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58
Citations
13186
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10544
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Overview

Franz Worek is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on topics related to pesticide exposure, neurotoxicology, and environmental toxicology.

Worek's work spans several key scientific fields and subfields, including:

  • Agricultural and Biological Sciences
  • Biochemistry, Genetics and Molecular Biology
  • Plant Science
  • Molecular Biology
  • Insect Science
  • Pharmacology
  • Pollution

The main topics covered in their research incorporate:

  • Pesticide Exposure and Toxicity
  • Insect and Pesticide Research
  • Cholinesterase and Neurodegenerative Diseases
  • Pesticide and Herbicide Environmental Studies
  • Environmental Toxicology and Ecotoxicology
  • Nicotinic Acetylcholine Receptors Study
  • Ion channel regulation and function

Frequent publication venues for Franz Worek include:

  • Toxicology Letters
  • Archives of Toxicology
  • Chemico-Biological Interactions
  • Chemistry - A European Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Among their recent papers are:

  • Organophosphorus compounds and oximes: a critical review, 2020, Archives of Toxicology
  • Diagnostics and treatment of nerve agent poisoning-current status and future developments, 2020, Annals of the New York Academy of Sciences
  • Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense, 2021, Archives of Toxicology
  • A case report of cholinesterase inhibitor poisoning: cholinesterase activities and analytical methods for diagnosis and clinical decision making, 2020, Archives of Toxicology
  • Optimization of long-term cold storage of rat precision-cut lung slices with a tissue preservation solution, 2021, American Journal of Physiology-Lung Cellular and Molecular Physiology

Regular collaborators in Worek's research include colleagues such as Horst Thiermann, Timo Wille, Dirk Steinritz, Niko Amend, and Karin V. Niessen. Coauthor joint publications reflect ongoing work in toxicology and related biomedical fields.

Best Publications

  • Improved determination of acetylcholinesterase activity in human whole blood.

    Franz Worek;Ulrike Mast;Daniela Kiderlen;Christine Diepold

  • Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes

    Franz Worek;Horst Thiermann;Ladislaus Szinicz;Peter Eyer

  • Molar absorption coefficients for the reduced Ellman reagent: reassessment.

    Peter Eyer;Franz Worek;Daniela Kiderlen;Goran Sinko

  • Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study

    Michael Eddleston;Michael Eddleston;Peter Eyer;Franz Worek;Fahim Mohamed

  • Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.

    F. Worek;G. Reiter;P. Eyer;L. Szinicz

  • Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model

    Sylvia Wagner;Anja Zensi;Sascha L. Wien;Sabrina E. Tschickardt

  • Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network.

    Harald John;Marcel J. van der Schans;Marianne Koller;Helma E. T. Spruit

  • Respiratory failure in acute organophosphorus pesticide self-poisoning

    Michael Eddleston;F Mohamed;Jamie Davies;P Eyer

  • Diagnostic aspects of organophosphate poisoning.

    Franz Worek;Marianne Koller;Horst Thiermann;Ladislaus Szinicz

  • Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics.

    F. Worek;C. Diepold;P. Eyer

  • Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning

    F. Worek;M. Bäcker;H. Thiermann;L. Szinicz

  • Modern strategies in therapy of organophosphate poisoning.

    H. Thiermann;L. Szinicz;F. Eyer;F. Worek

  • The value of novel oximes for treatment of poisoning by organophosphorus compounds.

    Franz Worek;Horst Thiermann

  • Oximes in organophosphate poisoning: 60 years of hope and despair.

    Franz Worek;Horst Thiermann;Timo Wille

  • Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds

    F Worek;R Widmann;O Knopff;L Szinicz

  • Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase.

    N. Aurbek;H. Thiermann;L. Szinicz;P. Eyer

  • Limitations and challenges in treatment of acute chemical warfare agent poisoning

    Horst Thiermann;Franz Worek;Kai Kehe

  • Recent advances in evaluation of oxime efficacy in nerve agent poisoning by in vitro analysis.

    F. Worek;P. Eyer;N. Aurbek;L. Szinicz

  • Determination of acetylcholinesterase activity by the Ellman assay: A versatile tool for in vitro research on medical countermeasures against organophosphate poisoning

    Franz Worek;Peter Eyer;Horst Thiermann

  • LC-MS-based procedures for monitoring of toxic organophosphorus compounds and verification of pesticide and nerve agent poisoning

    Harald John;Franz Worek;Horst Thiermann

  • Human parathion poisoning. A toxicokinetic analysis.

    Florian Eyer;Veronika Meischner;Daniela Kiderlen;Horst Thiermann

  • Correlation between red blood cell acetylcholinesterase activity and neuromuscular transmission in organophosphate poisoning

    Horst Thiermann;Ladislaus Szinicz;Peter Eyer;Thomas Zilker

Frequent Co-Authors

Horst Thiermann
Horst Thiermann Ludwig-Maximilians-Universität München
Michael Eddleston
Michael Eddleston University of Edinburgh
Nicholas A. Buckley
Nicholas A. Buckley University of Sydney
Joel L. Sussman
Joel L. Sussman Weizmann Institute of Science
Dan S. Tawfik
Dan S. Tawfik Weizmann Institute of Science
Florian Nachon
Florian Nachon Centre national de la recherche scientifique, CNRS
Kamil Kuca
Kamil Kuca University of Hradec Králové
Thomas Gudermann
Thomas Gudermann Ludwig-Maximilians-Universität München
Arne Skerra
Arne Skerra Technical University of Munich
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford

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