His scientific interests lie mostly in Obidoxime, Acetylcholinesterase, Nerve agent, Pralidoxime and Pharmacology. He combines subjects such as Cyclosarin, Tabun, Soman, Oxime and Paraoxon with his study of Obidoxime. His Acetylcholinesterase research integrates issues from Organophosphate poisoning and Organophosphate.
His Nerve agent research includes elements of Chromatography, Sample preparation and Liquid chromatography–mass spectrometry. His work deals with themes such as Sulfur mustard and Intensive care medicine, which intersect with Pralidoxime. His studies deal with areas such as Sarin and Atropine as well as Pharmacology.
His primary areas of investigation include Acetylcholinesterase, Nerve agent, Pharmacology, Obidoxime and Oxime. His Acetylcholinesterase study improves the overall literature in Biochemistry. He has included themes like Sarin and Chromatography in his Nerve agent study.
His study focuses on the intersection of Pharmacology and fields such as Atropine with connections in the field of Toxicity. His work in Obidoxime tackles topics such as Pralidoxime which are related to areas like Animal data. His Oxime research is multidisciplinary, incorporating perspectives in Organophosphorus compound and Stereochemistry.
His main research concerns Nerve agent, Pharmacology, Acetylcholinesterase, Acetylcholine and Sarin. The concepts of his Nerve agent study are interwoven with issues in Chromatography and Soman. His Pharmacology study combines topics in areas such as Muscarinic acetylcholine receptor, Atropine, Sulfur mustard and Obidoxime, Aché.
His study in Obidoxime is interdisciplinary in nature, drawing from both Pralidoxime, Whole blood and Physical chemistry. Franz Worek studies Butyrylcholinesterase, a branch of Acetylcholinesterase. In his research, Asthma and COPD is intimately related to Intensive care medicine, which falls under the overarching field of Sarin.
Franz Worek spends much of his time researching Nerve agent, Acetylcholinesterase, Pharmacology, Chromatography and Cysteine. His study in the field of Obidoxime also crosses realms of Alicyclobacillus acidocaldarius. His Obidoxime research is multidisciplinary, relying on both Whole blood, Butyrylcholinesterase and Cholinesterase.
Sarin is the focus of his Acetylcholinesterase research. His work carried out in the field of Pharmacology brings together such families of science as Muscarinic acetylcholine receptor, Airway and Organophosphate. He interconnects Cyclosarin and Paraoxon in the investigation of issues within Oxime.
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Improved determination of acetylcholinesterase activity in human whole blood.
Franz Worek;Ulrike Mast;Daniela Kiderlen;Christine Diepold.
Clinica Chimica Acta (1999)
Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes
Franz Worek;Horst Thiermann;Ladislaus Szinicz;Peter Eyer.
Biochemical Pharmacology (2004)
Molar absorption coefficients for the reduced Ellman reagent: reassessment.
Peter Eyer;Franz Worek;Daniela Kiderlen;Goran Sinko.
Analytical Biochemistry (2003)
Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study
Michael Eddleston;Michael Eddleston;Peter Eyer;Franz Worek;Fahim Mohamed.
The Lancet (2005)
Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.
F. Worek;G. Reiter;P. Eyer;L. Szinicz.
Archives of Toxicology (2002)
Respiratory failure in acute organophosphorus pesticide self-poisoning
Michael Eddleston;F Mohamed;Jamie Davies;P Eyer.
QJM: An International Journal of Medicine (2006)
Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model
Sylvia Wagner;Anja Zensi;Sascha L. Wien;Sabrina E. Tschickardt.
PLOS ONE (2012)
Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics.
F Worek;C Diepold;P Eyer.
Archives of Toxicology (1999)
Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning
F. Worek;M. Bäcker;H. Thiermann;L. Szinicz.
Human & Experimental Toxicology (1997)
Diagnostic aspects of organophosphate poisoning.
Franz Worek;Marianne Koller;Horst Thiermann;Ladislaus Szinicz.
Toxicology (2005)
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