D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 51 Citations 9,154 210 World Ranking 8380 National Ranking 650

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Internal medicine
  • Biochemistry

His scientific interests lie mostly in Obidoxime, Acetylcholinesterase, Nerve agent, Pralidoxime and Pharmacology. He combines subjects such as Cyclosarin, Tabun, Soman, Oxime and Paraoxon with his study of Obidoxime. His Acetylcholinesterase research integrates issues from Organophosphate poisoning and Organophosphate.

His Nerve agent research includes elements of Chromatography, Sample preparation and Liquid chromatography–mass spectrometry. His work deals with themes such as Sulfur mustard and Intensive care medicine, which intersect with Pralidoxime. His studies deal with areas such as Sarin and Atropine as well as Pharmacology.

His most cited work include:

  • Improved determination of acetylcholinesterase activity in human whole blood. (411 citations)
  • Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes (365 citations)
  • Molar absorption coefficients for the reduced Ellman reagent: reassessment. (346 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Acetylcholinesterase, Nerve agent, Pharmacology, Obidoxime and Oxime. His Acetylcholinesterase study improves the overall literature in Biochemistry. He has included themes like Sarin and Chromatography in his Nerve agent study.

His study focuses on the intersection of Pharmacology and fields such as Atropine with connections in the field of Toxicity. His work in Obidoxime tackles topics such as Pralidoxime which are related to areas like Animal data. His Oxime research is multidisciplinary, incorporating perspectives in Organophosphorus compound and Stereochemistry.

He most often published in these fields:

  • Acetylcholinesterase (46.84%)
  • Nerve agent (45.35%)
  • Pharmacology (41.26%)

What were the highlights of his more recent work (between 2016-2021)?

  • Nerve agent (45.35%)
  • Pharmacology (41.26%)
  • Acetylcholinesterase (46.84%)

In recent papers he was focusing on the following fields of study:

His main research concerns Nerve agent, Pharmacology, Acetylcholinesterase, Acetylcholine and Sarin. The concepts of his Nerve agent study are interwoven with issues in Chromatography and Soman. His Pharmacology study combines topics in areas such as Muscarinic acetylcholine receptor, Atropine, Sulfur mustard and Obidoxime, Aché.

His study in Obidoxime is interdisciplinary in nature, drawing from both Pralidoxime, Whole blood and Physical chemistry. Franz Worek studies Butyrylcholinesterase, a branch of Acetylcholinesterase. In his research, Asthma and COPD is intimately related to Intensive care medicine, which falls under the overarching field of Sarin.

Between 2016 and 2021, his most popular works were:

  • Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network. (77 citations)
  • Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts. (17 citations)
  • Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. (13 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Internal medicine
  • Biochemistry

Franz Worek spends much of his time researching Nerve agent, Acetylcholinesterase, Pharmacology, Chromatography and Cysteine. His study in the field of Obidoxime also crosses realms of Alicyclobacillus acidocaldarius. His Obidoxime research is multidisciplinary, relying on both Whole blood, Butyrylcholinesterase and Cholinesterase.

Sarin is the focus of his Acetylcholinesterase research. His work carried out in the field of Pharmacology brings together such families of science as Muscarinic acetylcholine receptor, Airway and Organophosphate. He interconnects Cyclosarin and Paraoxon in the investigation of issues within Oxime.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Improved determination of acetylcholinesterase activity in human whole blood.

Franz Worek;Ulrike Mast;Daniela Kiderlen;Christine Diepold.
Clinica Chimica Acta (1999)

643 Citations

Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes

Franz Worek;Horst Thiermann;Ladislaus Szinicz;Peter Eyer.
Biochemical Pharmacology (2004)

561 Citations

Molar absorption coefficients for the reduced Ellman reagent: reassessment.

Peter Eyer;Franz Worek;Daniela Kiderlen;Goran Sinko.
Analytical Biochemistry (2003)

482 Citations

Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study

Michael Eddleston;Michael Eddleston;Peter Eyer;Franz Worek;Fahim Mohamed.
The Lancet (2005)

411 Citations

Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.

F. Worek;G. Reiter;P. Eyer;L. Szinicz.
Archives of Toxicology (2002)

311 Citations

Respiratory failure in acute organophosphorus pesticide self-poisoning

Michael Eddleston;F Mohamed;Jamie Davies;P Eyer.
QJM: An International Journal of Medicine (2006)

232 Citations

Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model

Sylvia Wagner;Anja Zensi;Sascha L. Wien;Sabrina E. Tschickardt.
PLOS ONE (2012)

230 Citations

Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics.

F Worek;C Diepold;P Eyer.
Archives of Toxicology (1999)

213 Citations

Reappraisal of indications and limitations of oxime therapy in organophosphate poisoning

F. Worek;M. Bäcker;H. Thiermann;L. Szinicz.
Human & Experimental Toxicology (1997)

204 Citations

Diagnostic aspects of organophosphate poisoning.

Franz Worek;Marianne Koller;Horst Thiermann;Ladislaus Szinicz.
Toxicology (2005)

204 Citations

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