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Pierre-Yves Renard

Pierre-Yves Renard

D-Index & Metrics

Chemistry

D-Index
66
Citations
15101
World Ranking
7300
National Ranking
251

Overview

Pierre-Yves Renard was a researcher affiliated with the University of Rouen in France. Their work spanned multiple fields of study with a focus on Chemistry and Biochemistry, Genetics and Molecular Biology. Within these domains, their subfields of expertise included Organic Chemistry, Molecular Biology, Materials Chemistry, Pharmacology, and Plant Science.

The research topics covered by Pierre-Yves Renard included Click Chemistry and Applications, Pesticide Exposure and Toxicity, Cholinesterase and Neurodegenerative Diseases, Chemical Synthesis and Analysis, Lipid Membrane Structure and Behavior, Synthesis and Catalytic Reactions, and Molecular Sensors and Ion Detection.

Renard contributed to numerous research publications, with frequent appearances in venues such as The Cambridge Structural Database, Green Chemistry, Chemistry - A European Journal, Journal of Medicinal Chemistry, and European Journal of Organic Chemistry.

The following are some of the recent papers associated with their work:

  • Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice, 2020, Journal of Medicinal Chemistry
  • Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells, 2020, Cell Reports
  • Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning, 2020, ACS Chemical Neuroscience
  • Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies, 2020, Bioconjugate Chemistry
  • Chromogranin A preferential interaction with Golgi phosphatidic acid induces membrane deformation and contributes to secretory granule biogenesis, 2020, The FASEB Journal

Throughout their career, Pierre-Yves Renard collaborated frequently with a number of researchers. The most frequent co-authors include:

  • Cyrille Sabot
  • Ludovic Jean
  • Patricia Le Nahenec-Martel
  • Julien Legros
  • Émeline Tanguy

Best Publications

  • Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase.

    Florian Nachon;Eugénie Carletti;Cyril Ronco;Marie Trovaslet

  • Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

    Guillaume Mercey;Guillaume Mercey;Tristan Verdelet;Tristan Verdelet;Julien Renou;Julien Renou;Maria Kliachyna

  • New selective ligands of human cloned melatonin MT1 and MT2 receptors.

    Valérie Audinot;François Mailliet;Chantal Lahaye-Brasseur;Anne Bonnaud

  • Water-Soluble BODIPY Derivatives

    Song Lin Niu;Gilles Ulrich;Raymond Ziessel;Agneta Kiss

  • Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.

    Depreux P;Lesieur D;Mansour Ha;Morgan P

  • Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies

    Kévin Renault;Jean Wilfried Fredy;Pierre-Yves Renard;Cyrille Sabot

  • Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity.

    Stéphane Sabelle;Pierre-Yves Renard;Karine Pecorella;Sophie de Suzzoni-Dézard

  • High-throughput screening of enantioselective catalysts by immunoassay.

    Frédéric Taran;Cécile Gauchet;Barbara Mohar;Stéphane Meunier

  • Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle

    Ying Li;Feng Shan;Jin-Ming Wu;Guang-Shao Wu

  • Melatonin analogues as agonists and antagonists in the circadian system and other brain areas

    Shui-Wang Ying;Benjamin Rusak;Philippe Delagrange;Elisabeth Mocaër

  • Azo-Based Fluorogenic Probes for Biosensing and Bioimaging: Recent Advances and Upcoming Challenges.

    Arnaud Chevalier;Pierre-Yves Renard;Anthony Romieu;Anthony Romieu

  • Novel water-soluble near-infrared cyanine dyes: synthesis, spectral properties, and use in the preparation of internally quenched fluorescent probes.

    Cédric Bouteiller;Guillaume Clavé;Aude Bernardin;Bertrand Chipon

  • Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.

    Frédérique Touzeau;Axelle Arrault;Gérald Guillaumet;Elizabeth Scalbert

  • 7-Hydroxycoumarin−Hemicyanine Hybrids: A New Class of Far-Red Emitting Fluorogenic Dyes

    Jean-Alexandre Richard;Marc Massonneau;Pierre-Yves Renard;Anthony Romieu

  • Water‐Soluble Red‐Emitting Distyryl‐Borondipyrromethene (BODIPY) Dyes for Biolabeling

    Song-lin Niu;Cédrik Massif;Gilles Ulrich;Pierre-Yves Renard;Pierre-Yves Renard;Pierre-Yves Renard

  • Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion?

    Constantinos Pantos;Iordanis Mourouzis;Theodosios Saranteas;Guillaume Clavé

  • First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase.

    Guillaume Mercey;Guillaume Mercey;Tristan Verdelet;Tristan Verdelet;Géraldine Saint-André;Emilie Gillon

  • Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands.

    Valérie Wallez;Sophie Durieux-Poissonnier;Philippe Chavatte;Jean A. Boutin

  • Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure

    Xavier Brazzolotto;Marielle Wandhammer;Cyril Ronco;Marie Trovaslet

  • Synthesis of new pyrrolo(1,2-a)quinoxalines: potential non-peptide glucagon receptor antagonists

    Jean Guillon;Patrick Dallemagne;Bruno Pfeiffer;Pierre Renard

  • Structure-activity relationships of human urotensin II and related analogues on rat aortic ring contraction.

    Patricia Labarrère;David Chatenet;Jérôme Leprince;Céline Marionneau

Frequent Co-Authors

Florian Nachon
Florian Nachon Centre national de la recherche scientifique, CNRS
Charles Mioskowski
Charles Mioskowski Centre national de la recherche scientifique, CNRS
Christophe Créminon
Christophe Créminon Centre national de la recherche scientifique, CNRS
Jacques Grassi
Jacques Grassi French Alternative Energies and Atomic Energy Commission (CEA)
Raymond Ziessel
Raymond Ziessel University of Strasbourg
Manuela Bartolini
Manuela Bartolini University of Bologna
Gilles Ulrich
Gilles Ulrich École Normale Supérieure
Israel Silman
Israel Silman Weizmann Institute of Science
Patrick Masson
Patrick Masson Kazan Federal University
Nicolas Vitale
Nicolas Vitale Centre national de la recherche scientifique, CNRS

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