His primary areas of study are Cell biology, Exocytosis, Secretion, Phospholipase D and ADP ribosylation factor. The study incorporates disciplines such as Lipid bilayer fusion and Cell membrane in addition to Cell biology. His biological study spans a wide range of topics, including GTPase, Munc-18, Chromaffin cell, Phosphatidylinositol and GTP'.
Nicolas Vitale interconnects Cell fractionation, G protein and Immunoprecipitation in the investigation of issues within Secretion. His Phospholipase D research includes themes of PLD2, Phosphatidic acid, Internalization and Endosome. His ADP ribosylation factor research includes elements of Paxillin and Kinase.
His primary scientific interests are in Cell biology, Exocytosis, Phospholipase D, Secretion and Phosphatidic acid. Nicolas Vitale has included themes like Biochemistry and Lipid bilayer fusion in his Cell biology study. In his work, Lipid microdomain is strongly intertwined with Annexin A2, which is a subfield of Exocytosis.
As a part of the same scientific study, Nicolas Vitale usually deals with the Phospholipase D, concentrating on Intracellular and frequently concerns with Extracellular. In his study, Molecular biology is inextricably linked to G protein, which falls within the broad field of Secretion. The Phosphatidic acid study combines topics in areas such as Diacylglycerol kinase and Phosphorylation.
The scientist’s investigation covers issues in Cell biology, Phosphatidic acid, Phospholipase D, Exocytosis and Secretion. His is involved in several facets of Cell biology study, as is seen by his studies on Cell signaling, Endosome, GTPase, Extracellular and Golgi apparatus. His study in Phosphatidic acid is interdisciplinary in nature, drawing from both Lipid signaling, Diacylglycerol kinase, Nucleolus, Granule and Membrane lipids.
His work carried out in the field of Phospholipase D brings together such families of science as Neurosecretion, Phospholipid, Lipid bilayer fusion, Homeostasis and Intracellular. His Exocytosis research incorporates elements of Guanine, Neuroendocrine tumors, Hormone, Heterogeneous group and Rho GTPases. The various areas that Nicolas Vitale examines in his Secretion study include Catecholamine, Annexin A2, Actin, Phosphorylation and Hormone secreting.
His primary scientific interests are in Cell biology, Phosphatidic acid, Phospholipase D, Endosome and Extracellular. His Cell biology study combines topics in areas such as Cypa, Exocytosis and HEK 293 cells. Exocytosis is the subject of his research, which falls under Secretion.
His Phosphatidic acid research includes elements of Nucleolus, Lipid signaling and Ribonuclease. His work is dedicated to discovering how Phospholipase D, Intracellular are connected with Mode of action, Phagocytosis, Immunoprecipitation and Small GTPase and other disciplines. His studies in Endosome integrate themes in fields like Cyclophilin A, Phosphatidylinositol and Cell membrane.
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Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2.
Rania Ghossoub;Frédérique Lembo;Aude Rubio;Carole Baron Gaillard.
Nature Communications (2014)
beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.
Richard T. Premont;Audrey Claing;Nicolas Vitale;Jennifer L. R. Freeman.
Proceedings of the National Academy of Sciences of the United States of America (1998)
β-Arrestin-mediated ADP-ribosylation Factor 6 Activation and β2-Adrenergic Receptor Endocytosis
Audrey Claing;Wei Chen;William E. Miller;Nicolas Vitale.
Journal of Biological Chemistry (2001)
Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells
Nicolas Vitale;Anne‐Sophie Caumont;Sylvette Chasserot‐Golaz;Guangwei Du.
The EMBO Journal (2001)
Scrib Controls Cdc42 Localization and Activity to Promote Cell Polarization during Astrocyte Migration
Naël Osmani;Nicolas Vitale;Jean-Paul Borg;Sandrine Etienne-Manneville;Sandrine Etienne-Manneville.
Current Biology (2006)
Mammalian Scribble Forms a Tight Complex with the βPIX Exchange Factor
Stéphane Audebert;Christel Navarro;Claire Nourry;Sylvette Chasserot-Golaz.
Current Biology (2004)
Phospholipase D1 Production of Phosphatidic Acid at the Plasma Membrane Promotes Exocytosis of Large Dense-core Granules at a Late Stage
Maria Zeniou-Meyer;Naama Zabari;Uri Ashery;Sylvette Chasserot-Golaz.
Journal of Biological Chemistry (2007)
Regulated Exocytosis in Chromaffin Cells TRANSLOCATION OF ARF6 STIMULATES A PLASMA MEMBRANE-ASSOCIATED PHOSPHOLIPASE D
Anne-Sophie Caumont;Marie-Christine Galas;Nicolas Vitale;Dominique Aunis.
Journal of Biological Chemistry (1998)
Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs
Guangwei Du;Yelena M. Altshuller;Nicolas Vitale;Ping Huang.
Journal of Cell Biology (2003)
A role for phospholipase D1 in neurotransmitter release.
Yann Humeau;Nicolas Vitale;Sylvette Chasserot-Golaz;Jean-Luc Dupont.
Proceedings of the National Academy of Sciences of the United States of America (2001)
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Centre national de la recherche scientifique, CNRS
Centre national de la recherche scientifique, CNRS
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