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D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
27550
World Ranking
3137
National Ranking
241

Overview

Volker Gerke is a researcher affiliated with the University of Münster in Germany, with a primary focus in biochemistry, genetics, and molecular biology, as well as medicine. Their body of work spans several interconnected fields including molecular biology, cell biology, immunology, physiology, and hematology.

The scientist's research topics predominantly cover cellular transport and secretion, S100 proteins and annexins, lipid membrane structure and behavior, erythrocyte function and pathophysiology, cell adhesion molecules, platelet disorders and treatments, and cellular mechanics and interactions. These areas reflect a strong interest in membrane dynamics, protein functions related to cells, and physiological processes at the cellular level.

Recent publications by Volker Gerke and collaborators include notable papers such as:

  • "Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine" (2020, Emerging Microbes & Infections)
  • "Annexins-a family of proteins with distinctive tastes for cell signaling and membrane dynamics" (2024, Nature Communications)
  • "TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation" (2021, Molecular Cell)
  • "Weibel Palade Bodies: Unique Secretory Organelles of Endothelial Cells that Control Blood Vessel Homeostasis" (2021, Frontiers in Cell and Developmental Biology)
  • "Alarming and Calming: Opposing Roles of S100A8/S100A9 Dimers and Tetramers on Monocytes" (2022, Advanced Science)

Frequent coauthors of Gerke include Anna Lívia Linard Matos, Nikita Raj, Klaus Ebnet, Sergej Kudruk, and Ursula Rescher, each contributing to various collaborative projects with publication counts ranging from eight to thirteen joint works.

Gerke's research has been disseminated extensively in several scientific journals, with the most frequent publishing venues being Advanced Science, Frontiers in Cell and Developmental Biology, bioRxiv (Cold Spring Harbor Laboratory), Cellular and Molecular Life Sciences, and Chemistry - A European Journal.

In addition to journal articles, Gerke has contributed to book publications, including a title under Frontiers Media: "Cell compartments and intracellular trafficking of lipids and proteins: Impact on biomedicine" published in 2022.

Best Publications

  • Annexins: from structure to function.

    Volker Gerke;Stephen E. Moss

  • Annexins: linking Ca2+ signalling to membrane dynamics.

    Volker Gerke;Carl E. Creutz;Stephen E. Moss

  • PTEN-Mediated Apical Segregation of Phosphoinositides Controls Epithelial Morphogenesis through Cdc42

    Fernando Martin-Belmonte;Ama Gassama;Anirban Datta;Wei Yu

  • Annexins – unique membrane binding proteins with diverse functions

    Ursula Rescher;Volker Gerke

  • Identity of p36K phosphorylated upon Rous sarcoma virus transformation with a protein purified from brush borders; calcium-dependent binding to non-erythroid spectrin and F-actin.

    V. Gerke;K. Weber

  • Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton.

    Snezhana Oliferenko;Karin Paiha;Thomas Harder;Volker Gerke

  • Annexins and membrane dynamics.

    Volker Gerke;Stephen E Moss

  • MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.

    Thomas Vogl;Stephan Ludwig;Matthias Goebeler;Anke Strey

  • A Novel Ligand of the Formyl Peptide Receptor: Annexin I Regulates Neutrophil Extravasation by Interacting with the FPR

    Antje Walther;Kristina Riehemann;Volker Gerke

  • The crystal structure of a complex of p11 with the annexin II N-terminal peptide.

    Stéphane Réty;Jana Sopkova;Madalena Renouard;Dirk Osterloh

  • Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.

    Dorothee Viemann;Anke Strey;Annette Janning;Kerstin Jurk

  • Annexin II is a major component of fusogenic endosomal vesicles.

    N. Emans;J. P. Gorvel;C. Walter;V. Gerke

  • Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes

    Chunaram Choudhary;Jesper V. Olsen;Jesper V. Olsen;Christian Brandts;Jürgen Cox

  • The regulatory chain in the p36-kd substrate complex of viral tyrosine-specific protein kinases is related in sequence to the S-100 protein of glial cells.

    V Gerke;K Weber

  • Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

    Stan F.J. van de Graaf;Joost G.J. Hoenderop;Dimitra Gkika;Dennis Lamers

  • Annexin–Actin Interactions

    Matthew J. Hayes;Ursula Rescher;Volker Gerke;Stephen E. Moss

  • Characterization of the tubulin-tyrosine ligase.

    K Ersfeld;J Wehland;U Plessmann;H Dodemont

  • Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.

    F. Lang;K. Klingel;C. A. Wagner;C. Stegen

  • Calcium-dependent conformational changes in the 36-kDa subunit of intestinal protein I related to the cellular 36-kDa target of Rous sarcoma virus tyrosine kinase.

    V Gerke;K Weber

  • MRP8 AND MRP14 CONTROL MICROTUBULE REORGANIZATION DURING TRANSENDOTHELIAL MIGRATION OF PHAGOCYTES. running title: MRP8/MRP14 complexes and migration of phagocytes

    Dirk Foell;Volker Gerke;Wolfgang Nacken;Sabine Werner

Frequent Co-Authors

Klaus Weber
Klaus Weber Max Planck Society
Hans-Joachim Galla
Hans-Joachim Galla University of Münster
Bart Jan Ravoo
Bart Jan Ravoo University of Münster
Claudia Steinem
Claudia Steinem University of Göttingen
Stephan Ludwig
Stephan Ludwig University of Münster
Klaus Ebnet
Klaus Ebnet University of Münster
Stephen E. Moss
Stephen E. Moss University College London
Carsten Müller-Tidow
Carsten Müller-Tidow University Hospital Heidelberg
Armido Studer
Armido Studer University of Münster
Wolfgang E. Berdel
Wolfgang E. Berdel University of Münster

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