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Katherine A. Hajjar

Katherine A. Hajjar

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
19579
World Ranking
9016
National Ranking
4007

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Katherine A. Hajjar is affiliated with Cornell University in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on molecular biology aspects, with notable engagements in ophthalmology, hematology, pulmonary and respiratory medicine, and neurology.

The scientist's work covers diverse topics with a significant focus on the roles of S100 Proteins and Annexins. Additional areas of research include blood coagulation and thrombosis mechanisms, retinal diseases and treatments, glaucoma and retinal disorders, traumatic brain injury and neurovascular disturbances, neonatal respiratory health research, and immune response and inflammation.

Among recent publications, notable papers include:

  • "Annexin A2 in Inflammation and Host Defense," 2020, Cells
  • "Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization," 2021, Proceedings of the National Academy of Sciences
  • "Annexin A2 in Fibrinolysis, Inflammation and Fibrosis," 2021, International Journal of Molecular Sciences
  • "Reduced expression of annexin A2 is associated with impaired cell surface fibrinolysis and venous thromboembolism," 2021, Blood
  • "Blockade of Annexin A2 Prevents Early Microvasculopathy in Murine Models of Diabetic Retinopathy," 2023, Investigative Ophthalmology & Visual Science

Frequent co-authors collaborating with Hajjar include:

  • Dena Almeida
  • Valentina Dallacasagrande
  • Hana I. Lim
  • Huigen Chen
  • Maria T. DeSancho

Hajjar's research has been published in venues such as:

  • Blood
  • Cells
  • Proceedings of the National Academy of Sciences
  • International Journal of Molecular Sciences
  • Investigative Ophthalmology & Visual Science

They have been recognized by their peers through awards, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2014 and membership in the Association of American Physicians. These honors acknowledge contributions to scientific research without specifying the exact nature of the citation.

Best Publications

  • Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

    David Lyden;Koichi Hattori;Koichi Hattori;Sergio Dias;Carla Costa

  • The perivascular niche regulates breast tumour dormancy

    Cyrus M. Ghajar;Héctor Peinado;Hidetoshi Mori;Irina R. Matei

  • Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis.

    K A Hajjar;D Gavish;J L Breslow;R L Nachman

  • Molecular mechanisms of fibrinolysis.

    Gabriela Cesarman-Maus;Katherine A. Hajjar

  • Fibrinolysis and the control of blood coagulation.

    John C. Chapin;Katherine A. Hajjar

  • An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II.

    K A Hajjar;A T Jacovina;J Chacko

  • The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39.

    A. J. Marcus;M. J. Broekman;J. H. F. Drosopoulos;N. Islam

  • Annexin II and Bleeding in Acute Promyelocytic Leukemia

    Jill S. Menell;Gabriela M. Cesarman;Andrew T. Jacovina;Mary Ann McLaughlin

  • An endothelial cell receptor for plasminogen/tissue plasminogen activator (t-PA). II. Annexin II-mediated enhancement of t-PA-dependent plasminogen activation.

    G M Cesarman;C A Guevara;K A Hajjar

  • Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo.

    Qi Ling;Andrew T. Jacovina;Arunkumar Deora;Maria Febbraio

  • Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor.

    K A Hajjar

  • Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.

    R L Nachman;K A Hajjar;R L Silverstein;C A Dinarello

  • Binding of plasminogen to cultured human endothelial cells.

    K A Hajjar;P C Harpel;E A Jaffe;R L Nachman

  • Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells. A potential mechanism in thrombogenesis.

    O R Etingin;D P Hajjar;K A Hajjar;P C Harpel

  • An Annexin 2 Phosphorylation Switch Mediates p11-dependent Translocation of Annexin 2 to the Cell Surface

    Arunkumar B. Deora;Geri Kreitzer;Andrew T. Jacovina;Katherine A. Hajjar

  • Tissue plasminogen activator binding to the annexin II tail domain. Direct modulation by homocysteine

    Katherine A. Hajjar;Laura Mauri;Andrew T. Jacovina;Fengming Zhong

  • Binding of tissue plasminogen activator to cultured human endothelial cells.

    K A Hajjar;N M Hamel;P C Harpel;R L Nachman

  • High Affinity Binding of β2-Glycoprotein I to Human Endothelial Cells Is Mediated by Annexin II

    Keying Ma;Ronit Simantov;Jing Chuan Zhang;Roy Silverstein

  • Tumor necrosis factor-mediated release of platelet-derived growth factor from cultured endothelial cells.

    K A Hajjar;D P Hajjar;R L Silverstein;R L Nachman

  • Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase. Thromboregulation by endothelial cells.

    A J Marcus;L B Safier;K A Hajjar;H L Ullman

Frequent Co-Authors

David P. Hajjar
David P. Hajjar Cornell University
Roy L. Silverstein
Roy L. Silverstein Medical College of Wisconsin
John P. Leonard
John P. Leonard Cornell University
Laura Santambrogio
Laura Santambrogio Cornell University
Ralph L. Nachman
Ralph L. Nachman Cornell University
Eng H. Lo
Eng H. Lo Harvard University
Babette B. Weksler
Babette B. Weksler Cornell University
Shahin Rafii
Shahin Rafii Cornell University
David Lyden
David Lyden Cornell University
Kenneth I. Berns
Kenneth I. Berns University of Florida

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