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Hau C. Kwaan

Hau C. Kwaan

Northwestern University
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Cancer
  • Surgery

His primary areas of investigation include Internal medicine, Pathology, Cancer research, Immunology and Platelet. The study incorporates disciplines such as Gastroenterology and Endocrinology in addition to Internal medicine. His studies deal with areas such as Microcirculation, In vitro, Hemorheology and Hyperviscosity syndrome as well as Pathology.

His work deals with themes such as Cancer, Metastasis, Tissue factor, Urokinase receptor and Fibrinolysis, which intersect with Cancer research. His research integrates issues of Acute promyelocytic leukemia and Disseminated intravascular coagulation in his study of Immunology. His Platelet research is multidisciplinary, incorporating elements of Diagnostico diferencial, Pathophysiology and Plasmapheresis.

His most cited work include:

  • Thrombotic Thrombocytopenic Purpura Associated with Ticlopidine: A Review of 60 Cases (368 citations)
  • Increased platelet aggregation in diabetes mellitus. (358 citations)
  • The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin (287 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Immunology, Pathology, Fibrinolysis and Surgery. His Internal medicine research is multidisciplinary, incorporating perspectives in Gastroenterology and Endocrinology. His Immunology research integrates issues from Acute promyelocytic leukemia, Disseminated intravascular coagulation and Tissue factor.

His Fibrinolysis study combines topics in areas such as Plasminogen activator, Tissue plasminogen activator, Bioinformatics and Fibrin. His Plasminogen activator research is multidisciplinary, relying on both Molecular biology, Cancer research, Plasmin and Urokinase. In his study, Coagulopathy is strongly linked to Intensive care medicine, which falls under the umbrella field of Thrombosis.

He most often published in these fields:

  • Internal medicine (35.99%)
  • Immunology (22.53%)
  • Pathology (22.80%)

What were the highlights of his more recent work (between 2008-2021)?

  • Internal medicine (35.99%)
  • Immunology (22.53%)
  • Thrombosis (15.66%)

In recent papers he was focusing on the following fields of study:

Hau C. Kwaan mostly deals with Internal medicine, Immunology, Thrombosis, Intensive care medicine and Acute promyelocytic leukemia. His Internal medicine research incorporates elements of Gastroenterology and Oncology. The concepts of his Immunology study are interwoven with issues in Apoptosis, Fibrinolysis, Cumulative incidence and Hazard ratio.

Hau C. Kwaan has included themes like Plasminogen activator, Tissue plasminogen activator and Bioinformatics in his Fibrinolysis study. His research on Thrombosis also deals with topics like

  • Hemostasis which is related to area like Pathology, Disseminated intravascular coagulation, Introductory Journal Article, Pathogenesis and Cell-Derived Microparticles,
  • Cancer which is related to area like Cancer research and Angiogenesis. He interconnects Urokinase receptor and Plasmin in the investigation of issues within Cancer research.

Between 2008 and 2021, his most popular works were:

  • The Role of Plasminogen-Plasmin System in Cancer (106 citations)
  • The coagulopathy of acute promyelocytic leukaemia revisited (101 citations)
  • Early Platelet Transfusion Improves Platelet Activity and May Improve Outcomes After Intracerebral Hemorrhage (97 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Cancer
  • Surgery

His primary areas of study are Immunology, Internal medicine, Acute promyelocytic leukemia, Coagulopathy and Intensive care medicine. His Immunology study combines topics from a wide range of disciplines, such as Hemostasis, Fibrinolysis and Tissue plasminogen activator. His Fibrinolysis study incorporates themes from Transmission, Lung pathology and Plasmin.

His Tissue plasminogen activator research also works with subjects such as

  • Antifibrinolytic which intersects with area such as Plasminogen activator, Tissue factor, Oncology and Disseminated intravascular coagulation,
  • Annexin A2 that intertwine with fields like Metastasis and Urokinase receptor. His studies in Internal medicine integrate themes in fields like Gastroenterology and Cardiology. His Acute promyelocytic leukemia research includes elements of Leukemia and Chemotherapy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Thrombotic Thrombocytopenic Purpura Associated with Ticlopidine: A Review of 60 Cases

Charles L. Bennett;Peter D. Weinberg;Karine Rozenberg-Ben-Dror;Karine Rozenberg-Ben-Dror;Paul R. Yarnold.
Annals of Internal Medicine (1998)

544 Citations

Effect of warfarin anticoagulation on survival in carcinoma of the lung, colon, head and neck, and prostate. Final report of VA Cooperative Study #75.

Leo R. Zacharski;William G. Henderson;Frederick R. Rickles;Walter B. Forman.
Cancer (1984)

435 Citations

Reassessing the hemostatic disorder associated with acute promyelocytic leukemia.

Martin S. Tallman;Hau C. Kwaan.
Blood (1992)

408 Citations

Increased platelet aggregation in diabetes mellitus.

H C Kwaan;J A Colwell;J A Colwell;J A Colwell;S Cruz;S Cruz;S Cruz;N Suwanwela;N Suwanwela;N Suwanwela.
Journal of Laboratory and Clinical Medicine (1972)

397 Citations

The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin

Stephen Gately;Przemyslaw Twardowski;M. Sharon Stack;Deborah L. Cundiff.
Proceedings of the National Academy of Sciences of the United States of America (1997)

385 Citations

Effect of Warfarin on Survival in Small Cell Carcinoma of the Lung: Veterans Administration Study No. 75

Leo R. Zacharski;William G. Henderson;Frederick R. Rickles;Walter B. Forman.
JAMA (1981)

281 Citations

Human Prostate Carcinoma Cells Express Enzymatic Activity That Converts Human Plasminogen to the Angiogenesis Inhibitor, Angiostatin

Stephen Gately;Przemyslaw Twardowski;M. Sharon Stack;Matthew Patrick.
Cancer Research (1996)

281 Citations

The plasminogen-plasmin system in malignancy

Hau C. Kwaan.
Cancer and Metastasis Reviews (1992)

248 Citations

Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model.

Gerald A. Soff;Judith Sanderowitz;Stephen Gately;Elaine Verrusio.
Journal of Clinical Investigation (1995)

231 Citations

Plasminogen activator activity in cultures from human tissues. An immunological and histochemical study

Maria B. Bernik;Hau C. Kwaan.
Journal of Clinical Investigation (1969)

196 Citations

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