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Biology and Biochemistry

D-Index
54
Citations
10106
World Ranking
15662
National Ranking
379

Overview

Jan Voorberg is affiliated with the University of Amsterdam in the Netherlands, with a primary research focus in the field of Medicine. Their work spans multiple subfields including Hematology, Immunology, Genetics, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

Their research encompasses a range of topics, notably:

  • Platelet Disorders and Treatments
  • Complement system in diseases
  • Hemophilia Treatment and Research
  • Blood groups and transfusion
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Monoclonal and Polyclonal Antibodies Research
  • Renal Diseases and Glomerulopathies

Voorberg's published papers include the following recent works:

  • "PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease," 2021, Journal of Thrombosis and Haemostasis
  • "Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura," 2020, Blood
  • "Tolerating Factor VIII: Recent Progress," 2020, Frontiers in Immunology
  • "Orchestration of Primary Hemostasis by Platelet and Endothelial Lysosome-Related Organelles," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies," 2021, Blood Advances

Frequent coauthors contributing to their research include Ruben Bierings, Frank W.G. Leebeek, Karin Fijnvandraat, Karen Vanhoorelbeke, and Jeroen Eikenboom.

The main venues where Voorberg's work is published are:

  • Journal of Thrombosis and Haemostasis
  • Research and Practice in Thrombosis and Haemostasis
  • Blood
  • Blood Advances
  • Frontiers in Immunology

Best Publications

  • Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V

    J. Voorberg;J. Roelse;K. Mertens;J.A. van Mourik

  • KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

    Rob J. Dekker;Reinier A. Boon;Mariska G. Rondaij;Astrid Kragt

  • Dynamics and Plasticity of Weibel-Palade Bodies in Endothelial Cells

    Mariska G. Rondaij;Ruben Bierings;Astrid Kragt;Jan A. van Mourik

  • Functional architecture of Weibel-Palade bodies

    Karine M. Valentijn;J. Evan Sadler;Jack A. Valentijn;Jan Voorberg

  • Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

    W. J. M. Van De Ven;J. Voorberg;R. Fontijn;H. Pannekoek

  • Quantitative analysis of von Willebrand factor propeptide release in vivo: effect of experimental endotoxemia and administration of 1- deamino-8-D-arginine vasopressin in humans

    A. Borchiellini;K. Fijnvandraat;J. W. Ten Cate;D. Pajkrt

  • Emerging Concepts in Immune Thrombocytopenia.

    Maurice Swinkels;Maaike Rijkers;Jan Voorberg;Gestur Vidarsson

  • Biogenesis and exocytosis of Weibel-Palade bodies.

    Jan A. van Mourik;Thalia Romani de Wit;Jan Voorberg

  • Assembly and routing of von Willebrand factor variants: the requirements for disulfide-linked dimerization reside within the carboxy-terminal 151 amino acids.

    J Voorberg;R Fontijn;J Calafat;H Janssen

  • Establishment of outgrowth endothelial cells from peripheral blood

    Javier Martin-Ramirez;Menno Hofman;Maartje van den Biggelaar;Robert P Hebbel

  • Domains involved in multimer assembly of von willebrand factor (vWF): multimerization is independent of dimerization.

    J. Voorberg;R. Fontijn;J.A. van Mourik;H. Pannekoek

  • An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF.

    Wouter Pos;James T. B. Crawley;Rob Fijnheer;Jan Voorberg

  • Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms.

    Arnaud Echard;Frank J.M. Opdam;Hubert J.P.C. de Leeuw;Florence Jollivet

  • The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura.

    Brenda M. Luken;Ellen A.M. Turenhout;Janine J.J. Hulstein;Jan A. Van Mourik

  • Biogenesis of von Willebrand factor-containing organelles in heterologous transfected CV-1 cells.

    J Voorberg;R Fontijn;J Calafat;H Janssen

  • IgG subclasses of anti‐FVIII antibodies during immune tolerance induction in patients with hemophilia A

    Pauline M. W. van Helden;H. Marijke van den Berg;Samantha C. Gouw;Paul H. P. Kaijen

  • Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies

    Dorothee van Breevoort;Ellen L. van Agtmaal;Bieuwke S. Dragt;Jacqueline Klein Gebbinck

  • Real-Time Imaging of the Dynamics and Secretory Behavior of Weibel-Palade Bodies

    Thalia Romani de Wit;Mariska G. Rondaij;Peter L. Hordijk;Jan Voorberg

  • PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease

    Xiaosong Liu;Tom Arfman;Kanin Wichapong;Chris P. M. Reutelingsperger

  • KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

    Reinier A. Boon;Rob J. Dekker;Mariska G. Rondaij;Oscar L. Volger

Frequent Co-Authors

J. A. Van Mourik
J. A. Van Mourik University of Amsterdam
Hans Pannekoek
Hans Pannekoek University of Amsterdam
Bernhard Lämmle
Bernhard Lämmle University of Bern
Abraham J. Koster
Abraham J. Koster Leiden University Medical Center
Peter L. Hordijk
Peter L. Hordijk University of Amsterdam
Flora Peyvandi
Flora Peyvandi University of Milan
G. Kaplanski
G. Kaplanski Hôpital de la Conception
Hans Janssen
Hans Janssen KU Leuven

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