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Biology and Biochemistry

D-Index
75
Citations
16822
World Ranking
5419
National Ranking
153

Overview

Peter J. Lenting is affiliated with the University of Paris-Saclay in France and specializes in medical research with a strong focus on hematology. Their work spans multiple subfields including hematology, genetics, immunology, surgery, and molecular biology. The primary domain of their research lies within medicine, with a particular emphasis on blood-related disorders and mechanisms.

The scientist's research topics cover a broad spectrum of hematological and coagulation aspects. These include:

  • Platelet Disorders and Treatments
  • Hemophilia Treatment and Research
  • Blood Coagulation and Thrombosis Mechanisms
  • Blood Groups and Transfusion
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Complement System in Diseases
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema

Their publication record features contributions to prominent journals frequently associated with hematology and thrombosis. Key venues include:

  • Journal of Thrombosis and Haemostasis
  • Blood
  • Research and Practice in Thrombosis and Haemostasis
  • Haematologica
  • Blood Advances

Among recent papers authored or co-authored, notable entries demonstrate a focus on COVID-19-related vascular and coagulation research, as well as hemophilia monitoring and treatment. These papers include:

  • "Vascular Endothelial Damage in the Pathogenesis of Organ Injury in Severe COVID-19," 2021, Arteriosclerosis Thrombosis and Vascular Biology
  • "Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19," 2020, Journal of Thrombosis and Haemostasis
  • "Endotheliopathy Is Induced by Plasma From Critically Ill Patients and Associated With Organ Failure in Severe COVID-19," 2020, Circulation
  • "Laboratory monitoring of hemophilia A treatments: new challenges," 2020, Blood Advances
  • "A hemophilia A mouse model for the in vivo assessment of emicizumab function," 2020, Blood

Peter J. Lenting collaborates frequently with several researchers, expanding their work's interdisciplinary scope. Frequent co-authors include:

  • Cécile V. Denis
  • Olivier D. Christophe
  • Caterina Casari
  • Sophie Susen
  • Ivan Peyron

Best Publications

  • LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms

    Rashid Deane;Zhenhua Wu;Abhay Sagare;Judianne Davis

  • The life cycle of coagulation factor VIII in view of its structure and function.

    Peter J. Lenting;Jan A. van Mourik;Koen Mertens

  • Clearance of amyloid-β by circulating lipoprotein receptors

    Abhay Sagare;Rashid Deane;Robert D. Bell;Bradley Johnson

  • von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends

    Peter J. Lenting;Olivier D. Christophe;Cécile V. Denis

  • Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

    Robert Jan Lebbink;Talitha Eshuis-de Ruiter;Jelle Adelmeijer;Arjan B. Brenkman

  • Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients.

    Augusto B. Federici;Pier M. Mannucci;Giancarlo Castaman;Luciano Baronciani

  • Dimers of β2-Glycoprotein I Increase Platelet Deposition to Collagen via Interaction with Phospholipids and the Apolipoprotein E Receptor 2′

    Bianca C H Lutters;Ronald H W M Derksen;Winnie L Tekelenburg;Peter J Lenting

  • Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.

    Jenny McIntosh;Jenny McIntosh;Peter J. Lenting;Cecilia Rosales;Cecilia Rosales;Doyoung Lee

  • von Willebrand factor: the old, the new and the unknown

    P. J. Lenting;P. J. Lenting;C. Casari;C. Casari;O. D. Christophe;O. D. Christophe;C. V. Denis;C. V. Denis

  • Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?

    Peter J. Lenting;Cécile V. Denis;Olivier D. Christophe

  • The light chain of factor VIII comprises a binding site for low density lipoprotein receptor-related protein.

    P. J. Lenting;J. G. Neels;B. M. M. Van Den Berg;P. P. F. M. Clijsters

  • Identification of a binding site for blood coagulation factor IXa on the light chain of human factor VIII.

    P. J. Lenting;M.-J. S. H. Donath;J. A. Van Mourik;K. Mertens

  • Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin–mediated neutrophil rolling

    Jovanka Bestebroer;Miriam J. J. G. Poppelier;Laurien H. Ulfman;Peter J. Lenting

  • VWF protects FVIII from endocytosis by dendritic cells and subsequent presentation to immune effectors.

    Suryasarathi Dasgupta;Suryasarathi Dasgupta;Yohann Repessé;Yohann Repessé;Jagadeesh Bayry;Jagadeesh Bayry;Ana-Maria Navarrete;Ana-Maria Navarrete

  • von Willebrand factor and inflammation.

    C. Kawecki;P. J. Lenting;C. V. Denis

  • The sequence Glu1811-Lys1818 of human blood coagulation factor VIII comprises a binding site for activated factor IX.

    Peter J. Lenting;Jan-Willem H.P. van de Loo;Marie-José S.H. Donath;Jan A. van Mourik

  • P-selectin glycoprotein ligand 1 and β2-integrins cooperate in the adhesion of leukocytes to von Willebrand factor

    Ronan Pendu;Virginie Terraube;Olivier D. Christophe;Carl G. Gahmberg

  • A novel nanobody that detects the gain-of-function phenotype of von Willebrand factor in ADAMTS13 deficiency and von Willebrand disease type 2B.

    Janine J. J. Hulstein;Philip G. de Groot;Karen Silence;Agnès Veyradier

  • Of von Willebrand factor and platelets.

    Marijke Bryckaert;Marijke Bryckaert;Jean-Philippe Rosa;Jean-Philippe Rosa;Cécile V. Denis;Cécile V. Denis;Peter J. Lenting;Peter J. Lenting

  • Clearance mechanisms of von Willebrand factor and factor VIII

    P. J. Lenting;C. J. M. Van Schooten;C. V. Denis

Frequent Co-Authors

Philip G. de Groot
Philip G. de Groot Utrecht University
Eric Van Belle
Eric Van Belle Institut Pasteur
Bart Staels
Bart Staels University of Lille
Amit C. Nathwani
Amit C. Nathwani University College London
Linde Meyaard
Linde Meyaard Utrecht University
Ton Lisman
Ton Lisman University Medical Center Groningen
Hans Pannekoek
Hans Pannekoek University of Amsterdam
Hans Peter Schwarz
Hans Peter Schwarz Baxter (United States)
David Lillicrap
David Lillicrap Queen's University

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