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Biology and Biochemistry
Singapore
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
131
Citations
59977
World Ranking
391
National Ranking
3

Karl Tryggvason publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Karl Tryggvason sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 461 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Karl Tryggvason D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karl Tryggvason sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 131 D-Index — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Singapore Leader Award
  • 2025 - Research.com Biology and Biochemistry in Singapore Leader Award

Overview

Karl Tryggvason is affiliated with Duke NUS Graduate Medical School in Singapore and has contributed extensively to the fields of Medicine, Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields, including Molecular Biology, Nephrology, Surgery, Hematology, and Genetics.

Their scholarly work covers several main topics such as:

  • Renal Diseases and Glomerulopathies
  • Chronic Kidney Disease and Diabetes
  • Congenital Heart Defects Research
  • Tissue Engineering and Regenerative Medicine
  • Cell Adhesion Molecules Research
  • Acute Myeloid Leukemia Research
  • Genetic and Kidney Cyst Diseases

Recent publications by Karl Tryggvason include:

  • "A high-resolution map of human RNA translation," 2022, Molecular Cell
  • "Periportal macrophages protect against commensal-driven liver inflammation," 2024, Nature
  • "Viral proteases activate the CARD8 inflammasome in the human cardiovascular system," 2022, The Journal of Experimental Medicine
  • "Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression," 2021, Blood
  • "Podocyte-specific Crb2 knockout mice develop focal segmental glomerulosclerosis," 2021, Scientific Reports

Frequent collaborators include:

  • Lynn Yap (7 co-publications)
  • Enrico Petretto (7 co-publications)
  • Li Yen Chong (6 co-publications)
  • Swarnaseetha Adusumalli (5 co-publications)
  • Clarissa Tan (4 co-publications)

Their publications are frequently found in the following venues:

  • The Journal of Experimental Medicine (2 publications)
  • Molecular Cell (1 publication)
  • Nature (1 publication)
  • Blood (1 publication)
  • Scientific Reports (1 publication)

Karl Tryggvason's work integrates molecular and clinical perspectives, with a strong focus on mechanisms underlying kidney function and disease, as well as hematologic and cardiovascular research that intersects with inflammation and genetic factors. Their multidisciplinary approach reflects involvement in both fundamental molecular biology and applied clinical research.

Best Publications

  • Metastatic potential correlates with enzymatic degradation of basement membrane collagen.

    L. A. Liotta;K. Tryggvason;S. Garbisa;Ian Hart

  • Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome

    Marjo Kestilä;Ulla Lenkkeri;Minna Männikkö;Jane Lamerdin

  • Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma.

    Hynda K. Kleinman;Mary L. McGarvey;Lance A. Liotta;Pamela Gehron Robey

  • Alport's Syndrome, Goodpasture's Syndrome, and Type IV Collagen

    Billy G. Hudson;Karl Tryggvason;Munirathinam Sundaramoorthy;Eric G. Neilson;Eric G. Neilson

  • A simplified laminin nomenclature

    Monique Aumailley;Leena Bruckner-Tuderman;William G. Carter;Rainer Deutzmann

  • Identification of mutations in the COL4A5 collagen gene in Alport syndrome.

    David F. Barker;Sirkka Liisa Hostikka;Jing Zhou;Louise T. Chow

  • Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

    Zhongjun Zhou;Suneel S. Apte;Raija Soininen;Renhai Cao

  • A new nomenclature for the laminins.

    Robert E. Burgeson;Matthias Chiquet;Rainer Deutzmann;Peter Ekblom

  • Genomic instability in laminopathy-based premature aging

    Baohua Liu;Jianming Wang;Kui Ming Chan;Wai Mui Tjia

  • Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy.

    A Helbling-Leclerc;X Zhang;H Topaloglu;C Cruaud

  • Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis.

    B G Hudson;S T Reeders;K Tryggvason

  • Hereditary Proteinuria Syndromes and Mechanisms of Proteinuria

    Karl Tryggvason;Jaakko Patrakka;Jorma Wartiovaara

  • Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed.

    Ekaterina Morgunova;Ari Tuuttila;Ulrich Bergmann;Mikhail Isupov

  • X-linked Alport Syndrome Natural History in 195 Families and Genotype- Phenotype Correlations in Males

    Jean Philippe Jais;Bertrand Knebelmann;Iannis Giatras;Mario De Marchi

  • Proteolytic degradation of extracellular matrix in tumor invasion.

    K. Tryggvason;M. Höyhtyä;T. Salo

  • The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.

    Ganka Nikolova;Normund Jabs;Irena Konstantinova;Anna Domogatskaya

  • Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511

    Sergey Rodin;Anna Domogatskaya;Susanne Ström;Emil M Hansson

  • Defective Prelamin A Processing and Muscular and Adipocyte Alterations in Zmpste24 Metalloproteinase-Deficient Mice

    Alberto M. Pendás;Zhongjun Zhou;Juan Cadiñanos;José M.P. Freije

  • The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

    Heli Putaala;Raija Soininen;Pekka Kilpeläinen;Jorma Wartiovaara

  • Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages.

    Outi Elomaa;Maarit Kangas;Carin Sahlberg;Juha Tuukkanen

Frequent Co-Authors

Lance A. Liotta
Lance A. Liotta George Mason University
Outi Hovatta
Outi Hovatta Karolinska Institute
Christer Betsholtz
Christer Betsholtz Uppsala University
Jing Zhou
Jing Zhou Harvard University
Enrico Petretto
Enrico Petretto Duke NUS Graduate Medical School
Kari I. Kivirikko
Kari I. Kivirikko University of Oulu
Louise T. Chow
Louise T. Chow University of Alabama at Birmingham
Kjell Hultenby
Kjell Hultenby Karolinska Institute
Jean-Michel Foidart
Jean-Michel Foidart University of Liège
Thomas B. Shows
Thomas B. Shows Roswell Park Cancer Institute

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