World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
103
Citations
46097
World Ranking
7272
National Ranking
3811

Overview

Loren Laine is affiliated with Yale University in the United States and has an extensive publication record in the field of Medicine, focusing particularly on Gastroenterology. Their work spans several subfields including Surgery, Pulmonary and Respiratory Medicine, Oncology, and Cardiology and Cardiovascular Medicine.

Laine's research domains primarily cover topics such as Gastrointestinal Bleeding Diagnosis and Treatment, Gastroesophageal reflux and treatments, Helicobacter pylori-related gastroenterology studies, and Esophageal and GI Pathology. Additional areas of specialization include Antiplatelet Therapy and Cardiovascular Diseases as well as Eosinophilic Esophagitis.

The scientist has frequently published in prominent journals, with multiple contributions to:

  • Gastroenterology
  • The American Journal of Gastroenterology
  • Alimentary Pharmacology & Therapeutics
  • Gastrointestinal Endoscopy
  • arXiv (Cornell University)

Loren Laine's recent publications include:

  • ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding, 2021, The American Journal of Gastroenterology

In collaboration with other researchers, Laine has frequently coauthored works alongside:

  • Dennis Shung
  • Alan Barkun
  • Kisung You
  • Grigorios I. Leontiadis
  • Neil S. Zheng

Their main contributions to the medical literature include studies on the diagnosis and treatment of gastrointestinal bleeding, approaches to managing Helicobacter pylori infections, and guidelines for clinical practice related to upper gastrointestinal disorders. The research output includes both clinical guidelines and randomized clinical trials published in high-impact journals.

Best Publications

  • Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis

    Claire Bombardier;Loren Laine;Alise Reicin;Deborah Shapiro

  • Clopidogrel with or without Omeprazole in Coronary Artery Disease

    Deepak L. Bhatt;Deepak L. Bhatt;Byron L. Cryer;Charles F. Contant;Marc Cohen

  • SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease

    Loren Laine;Loren Laine;Tonya Kaltenbach;Alan Barkun;Kenneth R. McQuaid

  • Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: a meta-analysis.

    Deborah J. Cook;Gordon H. Guyatt;Gordon H. Guyatt;Bruno J. Salena;Bruno J. Salena;Loren A. Laine;Loren A. Laine

  • Bleeding peptic ulcer.

    Loren Laine;Walter L. Peterson

  • Endoscopic Ligation Compared with Sclerotherapy for Treatment of Esophageal Variceal Bleeding: A Meta-Analysis

    Loren Laine;Deborah Cook

  • Management of Patients With Ulcer Bleeding

    Loren Laine;Dennis M Jensen

  • Gastric Mucosal Defense and Cytoprotection: Bench to Bedside

    Loren Laine;Koji Takeuchi;Andrzej Tarnawski

  • Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient.

    Loren Laine

  • ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy.

    Ralf Metzger;Cynthia Gail Leichman;Kathleen D. Danenberg;Peter V. Danenberg

  • Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison

    Christopher P Cannon;Sean P Curtis;Garret A FitzGerald;Henry Krum

  • Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook

    Colleen R. Kelly;Stacy Kahn;Purna Kashyap;Loren Laine;Loren Laine

  • A randomized trial comparing the effect of rofecoxib, a cyclooxygenase 2–specific inhibitor, with that of ibuprofen on the gastroduodenal mucosa of patients with osteoarthritis

    Loren Laine;Sean Harper;Thomas Simon;Richard Bath

  • A systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures.

    Kenneth R. McQuaid;Loren Laine

  • Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials

    K.R. McQuaid;L. Laine

  • Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trial

    Christopher Hawkey;Loren Laine;Thomas Simon;Andre Beaulieu

  • Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival.

    Heinz-Josef Lenz;Cynthia Gail Leichman;Kathleen D. Danenberg;Peter V. Danenberg

  • Endoscopic Therapy for Bleeding Ulcers: An Evidence-Based Approach Based on Meta-Analyses of Randomized Controlled Trials

    Loren Laine;Kenneth R. McQuaid;Kenneth R. McQuaid

  • Serious lower gastrointestinal clinical events with nonselective NSAID or coxib use.

    Loren Laine;Laurine G. Connors;Alise Reicin;Christopher J. Hawkey

  • Endoscopic Ligation Compared with Sclerotherapy for Treatment of Esophageal Variceal Bleeding

    Loren Laine;Deborah Cook

Frequent Co-Authors

Christopher P. Cannon
Christopher P. Cannon Brigham and Women's Hospital
Alan N. Barkun
Alan N. Barkun McGill University Health Centre
Brennan M.R. Spiegel
Brennan M.R. Spiegel Cedars-Sinai Medical Center
Richard H. Hunt
Richard H. Hunt McMaster University
Thomas J. Schnitzer
Thomas J. Schnitzer Northwestern University
Christopher J. Hawkey
Christopher J. Hawkey University of Nottingham
William D. Chey
William D. Chey University of Michigan–Ann Arbor
Angel Lanas
Angel Lanas University of Zaragoza
Gary D. Wu
Gary D. Wu University of Pennsylvania
Claire Bombardier
Claire Bombardier University of Toronto

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