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Biology and Biochemistry

D-Index
52
Citations
8389
World Ranking
16820
National Ranking
1324

Overview

Egle Solito is affiliated with Queen Mary University of London in the United Kingdom. Their research spans several interconnected scientific fields including Medicine, Neuroscience, and Biochemistry, Genetics, and Molecular Biology. Within these broad categories, their focused subfields of study include Neurology, Molecular Biology, Physiology, Biological Psychiatry, and Cancer Research.

The core topics addressed by their work reflect a multidisciplinary approach involving Barrier Structure and Function Studies, Gut Microbiota and Health, Neuroinflammation and Neurodegeneration Mechanisms, Tryptophan and Brain Disorders, S100 Proteins and Annexins, Cancer, Hypoxia, and Metabolism, as well as Neurological Disease Mechanisms and Treatments.

Among the recent publications featuring Egle Solito are the following:

  • "Regulation of blood-brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide," 2021, Microbiome
  • "Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-β and tau pathology," 2021, Brain
  • "Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming," 2020, Nature Communications
  • "ALDOC- and ENO2- driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis," 2023, Journal of Experimental & Clinical Cancer Research
  • "The glucose transporter 2 regulates CD8+ T cell function via environment sensing," 2023, Nature Metabolism

Their collaborations are reflected in frequent co-authorship with several researchers, including Simon McArthur, Silvia Fanti, Federica M. Marelli-Berg, Antonio d'Amati, and Guosu Wang. These partnerships indicate a network active in interdisciplinary biomedical research.

Publications appear repeatedly in several venues with multiple contributions in Nature Metabolism, Circulation, Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), and Microbiome, pointing to a presence in journals focused on metabolism, immunology, vascular biology, and microbiome research.

Best Publications

  • Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.

    Mauro Perretti;Nan Chiang;Mylinh La;Iolanda M. Fierro

  • Microglia function in Alzheimer's disease

    Egle Solito;Magdalena Sastre

  • Annexin 1: more than an anti-phospholipase protein.

    Luca Parente;Egle Solito;Egle Solito

  • Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement

    Richard P. G. Hayhoe;Ahmad M. Kamal;Egle Solito;Roderick J. Flower

  • A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils

    Egle Solito;Ahmad Kamal;Francoise Russo-Marie;Julia C. Buckingham

  • Dexamethasone induces rapid serine-phosphorylation and membrane translocation of annexin 1 in a human folliculostellate cell line via a novel nongenomic mechanism involving the glucocorticoid receptor, protein kinase C, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase.

    Egle Solito;Abeda Mulla;John F. Morris;Helen C. Christian

  • Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: Effect of lipocortin 1

    Lina H. K. Lim;Egle Solito;Françoise Russo-Marie;Roderick J. Flower

  • Annexin A1: A Central Player in the Anti-Inflammatory and Neuroprotective Role of Microglia

    Simon McArthur;Enrico Cristante;Mario Paterno;Helen Christian

  • Regulation of blood-brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide.

    Lesley Hoyles;Matthew G. Pontifex;Ildefonso Rodriguez-Ramiro;Ildefonso Rodriguez-Ramiro;M. Areeb Anis-Alavi

  • Identification of an essential endogenous regulator of blood–brain barrier integrity, and its pathological and therapeutic implications

    Enrico Cristante;Simon McArthur;Claudio Mauro;Elisa Maggioli

  • Annexin A1: Uncovering the Many Talents of an Old Protein.

    Madeeha H Sheikh;Egle Solito

  • Involvement of the Receptor for Formylated Peptides in the in Vivo Anti-Migratory Actions of Annexin 1 and its Mimetics

    Mauro Perretti;Stephen J. Getting;Egle Solito;Philip M. Murphy

  • Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation

    Egle Solito;Catherine De Coupade;Silvia Canaider;Nicolas J Goulding

  • Estrogen protects the blood-brain barrier from inflammation-induced disruption and increased lymphocyte trafficking.

    E. Maggioli;S. McArthur;C. Mauro;J. Kieswich

  • Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface

    E. Solito;H. C. Christian;M. Festa;A. Mulla

  • Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U-937 cells.

    Egle Solito;Giovanni Raugei;Marialuisa Melli;Luca Parente

  • Anti-inflammatory mechanisms of the annexin A1 protein and its mimetic peptide Ac2-26 in models of ocular inflammation in vivo and in vitro.

    Ana Paula Girol;Kallyne K. O Mimura;Carine Cristiane Drewes;Simone Marques de Bolonheis

  • Annexin 1 expression and phosphorylation are upregulated during liver regeneration and transformation in antithrombin iii sv40 t large antigen transgenic mice

    Catherine de Coupade;Raphaëlle Gillet;Myriam Bennoun;Pascale Briand

  • Annexin 1 binds to U937 monocytic cells and inhibits their adhesion to microvascular endothelium: involvement of the alpha 4 beta 1 integrin.

    Egle Solito;Ignacio A. Romero;Stefano Marullo;Françoise Russo-Marie

  • Annexin 1, Glucocorticoids, and the Neuroendocrine–Immune Interface

    Julia C. Buckingham;Christopher D. John;Egle Solito;Tanya Tierney

Frequent Co-Authors

Mauro Perretti
Mauro Perretti Queen Mary University of London
Roderick J. Flower
Roderick J. Flower Queen Mary University of London
Chris P. M. Reutelingsperger
Chris P. M. Reutelingsperger Maastricht University
Pierluigi Paggiaro
Pierluigi Paggiaro University of Pisa
Andreas Hofmann
Andreas Hofmann University of Melbourne
Stefano Marullo
Stefano Marullo Université Paris Cité
Christoph Thiemermann
Christoph Thiemermann Queen Mary University of London
Federica M. Marelli-Berg
Federica M. Marelli-Berg Queen Mary University of London
Giorgio Stassi
Giorgio Stassi University of Palermo
Ignacio A. Romero
Ignacio A. Romero The Open University

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