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Chris P. M. Reutelingsperger

Chris P. M. Reutelingsperger

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
39652
World Ranking
2913
National Ranking
75

Overview

Chris P. M. Reutelingsperger is affiliated with Maastricht University in the Netherlands. Their research spans several fields within the biomedical sciences, focusing primarily on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The scientist's work is deeply embedded in the subfields of Immunology, Molecular Biology, Hematology, Pulmonary and Respiratory Medicine, and Genetics.

Their main research topics include:

  • S100 Proteins and Annexins
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Blood Coagulation and Thrombosis Mechanisms
  • Extracellular vesicles in disease
  • Complement system in diseases
  • Immune cells in cancer
  • Cell Adhesion Molecules Research

Chris P. M. Reutelingsperger has contributed publications extensively to a range of journals, with the most frequent venues being:

  • International Journal of Molecular Sciences (7 publications)
  • Journal of Thrombosis and Haemostasis (4 publications)
  • Scientific Reports (4 publications)
  • Cells (3 publications)
  • Cardiovascular Research (2 publications)

Among recent significant papers associated with Chris P. M. Reutelingsperger's research are:

  • "PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease," 2021, Journal of Thrombosis and Haemostasis
  • "Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification," 2020, Circulation Research
  • "Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation," 2020, Journal of Clinical Investigation
  • "The Anticoagulant and Nonanticoagulant Properties of Heparin," 2020, Thrombosis and Haemostasis
  • "Neutrophils and Contact Activation of Coagulation as Potential Drivers of COVID-19," 2020, Circulation

The scientist frequently collaborates with several researchers, including:

  • Gerry A. F. Nicolaes
  • Leon J. Schurgers
  • Pieter van Paassen
  • Kanin Wichapong
  • Sjoerd A.M.E.G. Timmermans

The research contributions of Chris P. M. Reutelingsperger reflect a multidisciplinary approach centered on immune mechanisms, molecular pathways, and vascular biology, with a special interest in coagulation, inflammation, and cellular signaling processes.

Best Publications

  • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V.

    István Vermes;Clemens Haanen;Helga Steffens-Nakken;Chris Reutelingsperger

  • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

    S. J. Martin;C. P. M. Reutelingsperger;A. J. Mcgahon;J. A. Rader

  • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis.

    G. Koopman;C. P. M. Reutelingsperger;G. A. M. Kuijten;R. M. J. Keehnen

  • Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure.

    Manon van Engeland;Luc J. W. Nieland;Frans C. S. Ramaekers;Bert Schutte

  • Flow cytometry of apoptotic cell death.

    I. Vermes;C. Haanen;C. Reutelingsperger

  • Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

    H A Andree;C P Reutelingsperger;R Hauptmann;H C Hemker

  • A NOVEL ASSAY TO MEASURE LOSS OF PLASMA MEMBRANE ASYMMETRY DURING APOPTOSIS OF ADHERENT CELLS IN CULTURE

    Manon van Engeland;Frans C.S. Ramaekers;Bert Schutte;Chris P.M. Reutelingsperger

  • Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro

    C. H. E. Homburg;M. De Haas;A. E. G. K. Von Dem Borne;A. J. Verhoeven

  • Visualisation of cell death in vivo in patients with acute myocardial infarction.

    L Hofstra;I H Liem;E A Dumont;Hendrikus Boersma

  • Vascular Smooth Muscle Cell Calcification Is Mediated by Regulated Exosome Secretion

    Alexander N. Kapustin;Martijn L.L. Chatrou;Ignat Drozdov;Ying Zheng

  • Past, Present, and Future of Annexin A5: From Protein Discovery to Clinical Applications*

    Hendrikus H Boersma;Bas L J H Kietselaer;Leo M L Stolk;Abdelkader Bennaghmouch

  • Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair

    Giovanna Leoni;Philipp-Alexander Neumann;Nazila Kamaly;Miguel Quiros

  • Novel conformation-specific antibodies against matrix gamma-carboxyglutamic acid (Gla) protein: undercarboxylated matrix Gla protein as marker for vascular calcification.

    Leon J. Schurgers;Kirsten J.F. Teunissen;Marjo H.J. Knapen;Martijn Kwaijtaal

  • Noninvasive Detection of Plaque Instability with Use of Radiolabeled Annexin A5 in Patients with Carotid-Artery Atherosclerosis

    Bas L.J.H. Kietselaer;Chris P.M. Reutelingsperger;Guido A.K. Heidendal;Mat J.A.P. Daemen

  • Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation

    S.M. van den Eijnde;M.J.B. van den Hoff;C.P.M. Reutelingsperger;W.L. van Heerde

  • Annexin V, the regulator of phosphatidylserine-catalyzed inflammation and coagulation during apoptosis

    C. P. M. Reutelingsperger;W. L. van Heerde

  • Targeting of Apoptotic Macrophages and Experimental Atheroma With Radiolabeled Annexin V A Technique With Potential for Noninvasive Imaging of Vulnerable Plaque

    Frank D. Kolodgie;Artiom Petrov;Renu Virmani;Navneet Narula

  • Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

    Giovanna Leoni;Ashfaqul Alam;Philipp Alexander Neumann;J. David Lambeth

  • The complexity of the phospholipid binding protein Annexin V.

    W. L. Van Heerde;P. G. De Groot;C. P. M. Reutelingsperger

  • Vitamin K-dependent carboxylation of matrix Gla-protein: a crucial switch to control ectopic mineralization

    Leon J. Schurgers;Jouni Uitto;Chris P. Reutelingsperger

Frequent Co-Authors

Leon J. Schurgers
Leon J. Schurgers Maastricht University
Jagat Narula
Jagat Narula Icahn School of Medicine at Mount Sinai
Mauro Perretti
Mauro Perretti Queen Mary University of London
Erik A.L. Biessen
Erik A.L. Biessen Maastricht University
Felix M. Mottaghy
Felix M. Mottaghy RWTH Aachen University
Jan Damoiseaux
Jan Damoiseaux Maastricht University
Egle Solito
Egle Solito Queen Mary University of London
Johan W. M. Heemskerk
Johan W. M. Heemskerk Maastricht University
Tilman M. Hackeng
Tilman M. Hackeng Maastricht University

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