2026 Ignacio A. Romero: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	76	5072	4685	378	350	234	19671

Overview

Ignacio A. Romero is affiliated with The Open University in the United Kingdom and conducts research primarily in the field of Medicine, with a focus on Neurology, Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, and Oncology.

Their research topics include:

Barrier Structure and Function Studies
Neurological Disease Mechanisms and Treatments
Cancer-related molecular mechanisms research
Advanced Radiotherapy Techniques
Cerebrospinal fluid and hydrocephalus
Intracerebral and Subarachnoid Hemorrhage Research
Prostate Cancer Treatment and Research

Ignacio A. Romero has published multiple papers in notable venues, including:

"Cerebrospinal fluid dynamics modulation by diet and cytokines in rats," 2020, Fluids and Barriers of the CNS
"Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice," 2021, Acta Neuropathologica Communications
"Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation," 2021, Pharmaceutics
"The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms," 2021, Molecular Oncology
"A human-derived neurovascular unit in vitro model to study the effects of cellular cross-talk and soluble factors on barrier integrity," 2022, Frontiers in Cellular Neuroscience

Frequent co-authors associated with Ignacio A. Romero include:

Cheryl A. Hawkes
David Male
David Roig-Carles
Francesco Crea
Radka Gromnicova

The scientist has published extensively in several recurring venues, such as:

arXiv (Cornell University)
Fluids and Barriers of the CNS
PLoS ONE
Annals of Oncology
Acta Neuropathologica Communications

Best Publications

Blood-brain barrier-specific properties of a human adult brain endothelial cell line

B. B. Weksler;E. A. Subileau;N. Perrière;P. Charneau

1465
Citations
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

Hans C. Helms;N. Joan Abbott;Malgorzata Burek;Romeo Cecchelli

714
Citations
The hCMEC/D3 cell line as a model of the human blood brain barrier

Babette Barbash Weksler;Ignacio A. Romero;Pierre-Olivier Couraud;Pierre-Olivier Couraud;Pierre-Olivier Couraud

660
Citations
BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function

L. M. Griep;F. Wolbers;B. de Wagenaar;P. M. ter Braak

615
Citations
Transporting therapeutics across the blood-brain barrier

N. Joan Abbott;Ignacio A. Romero

600
Citations
Chemokines control fat accumulation and leptin secretion by cultured human adipocytes.

C. C. Gerhardt;Ignacio A Romero;R. Cancello;L. Camoin

434
Citations
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

Gerty Schreibelt;Gijs Kooij;Arie Reijerkerk;Ruben van Doorn

421
Citations
Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models

Kathryn Hatherell;Pierre-Olivier Couraud;Ignacio A. Romero;Babette Weksler

381
Citations
The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies.

Birk Poller;Heike Gutmann;Stephan Krahenbuhl;Babette Weksler

360
Citations
Differential effects of hydrocortisone and TNFα on tight junction proteins in an in vitro model of the human blood-brain barrier

Carola Förster;Malgorzata Burek;Ignacio A. Romero;Babette Weksler

346
Citations
Immortalized Human Brain Endothelial Cells and Flow-Based Vascular Modeling: A Marriage of Convenience for Rational Neurovascular Studies:

Luca Cucullo;Pierre-Olivier Couraud;Babette Weksler;Babette Weksler;Ignacio-Andres Romero

324
Citations
Oxidative stress affects the junctional integrity of retinal pigment epithelial cells.

Tracey A. Bailey;Naheed Kanuga;Ignacio A. Romero;John Greenwood

315
Citations
MicroRNA-155 negatively affects blood–brain barrier function during neuroinflammation

Miguel Alejandro Lopez-Ramirez;Dongsheng Wu;Gareth Pryce;Julie E. Simpson

284
Citations
Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier

Nicola F. Fletcher;Garrick K. Wilson;Jacinta Murray;Ke Hu

284
Citations
Secretion of interleukin-1β by astrocytes mediates endothelin-1 and tumour necrosis factor-α effects on human brain microvascular endothelial cell permeability

Nathalie Didier;Ignacio A. Romero;Christophe Créminon;Anne Wijkhuisen

272
Citations
Regulation of chemokine receptor expression in human microglia and astrocytes.

Geraldine Flynn;Seema Maru;Jane Loughlin;Ignacio A Romero

263
Citations
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.

Vanja Vukic;Debbie Callaghan;Douglas Walker;Lih-Fen Lue

254
Citations
Meningococcal Type IV Pili Recruit the Polarity Complex to Cross the Brain Endothelium

Mathieu Coureuil;Guillain Mikaty;Florence Miller;Florence Miller;Hervé Lécuyer;Hervé Lécuyer

252
Citations
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

Tengfei Li;Jean-Pierre Bourgeois;Susanna Celli;Fabienne Glacial;Fabienne Glacial;Fabienne Glacial

239
Citations
Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells

Ignacio A. Romero;Katrina Radewicz;Emmanuelle Jubin;C.Charles Michel

230
Citations