Helga E. de Vries spends much of her time researching Blood–brain barrier, Multiple sclerosis, Pathology, Immunology and Cell biology. The concepts of her Blood–brain barrier study are interwoven with issues in Inflammation, Immune system, Encephalomyelitis, Endothelium and Tight junction. Her Multiple sclerosis research includes elements of Lesion, Neuroinflammation, Neuroscience and Reactive oxygen species.
Her Neuroinflammation study deals with Neurodegeneration intersecting with Mitochondrion. Her Pathology research is multidisciplinary, incorporating elements of Laminin and White matter, Magnetic resonance imaging. Her research in Cell biology intersects with topics in Endothelial stem cell, Cell migration and Cell adhesion.
Multiple sclerosis, Blood–brain barrier, Immunology, Neuroinflammation and Cell biology are her primary areas of study. Her studies deal with areas such as Inflammation, Central nervous system, Neuroscience and Pathology as well as Multiple sclerosis. Her study focuses on the intersection of Pathology and fields such as In vivo with connections in the field of In vitro.
Her studies in Blood–brain barrier integrate themes in fields like Basement membrane, Barrier function, Tight junction, Pharmacology and Epilepsy. Her work deals with themes such as Reactive oxygen species and Microglia, which intersect with Neuroinflammation. As a part of the same scientific family, Helga E. de Vries mostly works in the field of Cell biology, focusing on Endothelial stem cell and, on occasion, Human brain.
Helga E. de Vries mainly investigates Multiple sclerosis, Inflammation, Neuroinflammation, Cell biology and Central nervous system. Her Multiple sclerosis research incorporates themes from Myelin, Phagocyte, Neuroprotection and In vivo. Her study on Inflammation is covered under Immunology.
The Neuroinflammation study combines topics in areas such as Sphingolipid, Neurodegeneration, Microglia, Experimental autoimmune encephalomyelitis and Neuroscience. Her Cell biology study combines topics in areas such as Lipoprotein lipase, Blood–brain barrier and Metabotropic receptor. Helga E. de Vries has researched Central nervous system in several fields, including In vitro, Cerebrospinal fluid, Transient receptor potential channel and Chondroitin sulfate proteoglycan.
Helga E. de Vries mainly focuses on Multiple sclerosis, Cell biology, Central nervous system, Neurodegeneration and Inflammation. Multiple sclerosis is a subfield of Immunology that Helga E. de Vries explores. Her research in Cell biology intersects with topics in Endothelial stem cell and Neuroprotection.
The Central nervous system study combines topics in areas such as TRPM7, Transient receptor potential channel, In vitro and Chondroitin sulfate proteoglycan. In her study, Tight junction, Endothelium, Knockout mouse and Progressive supranuclear palsy is inextricably linked to Neuroinflammation, which falls within the broad field of Neurodegeneration. Her work deals with themes such as Stromal cell, Cerebrospinal fluid and CD8, Immune system, which intersect with Inflammation.
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The influence of cytokines on the integrity of the blood-brain barrier in vitro
Helga E. de Vries;Margret C.M. Blom-Roosemalen;Marijke van Oosten;Albert G. de Boer.
Journal of Neuroimmunology (1996)
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
Jorge Ivan Alvarez;Aurore Dodelet-Devillers;Hania Kebir;Igal Ifergan.
The Blood-Brain Barrier in Neuroinflammatory Diseases
Helga E. de Vries;Johan Kuiper;Albertus G. de Boer;Theo J. C. Van Berkel.
Pharmacological Reviews (1997)
Nrf2-induced antioxidant protection : A promising target to counteract ROS-mediated damage in neurodegenerative disease?
Helga E. de Vries;Maarten Witte;David Hondius;Annemieke J.M. Rozemuller.
Free Radical Biology and Medicine (2008)
The blood-brain barrier and its role in immune privilege in the central nervous system.
Joel S Pachter;Helga E de Vries;Zsuzsa Fabry.
Journal of Neuropathology and Experimental Neurology (2003)
Radical changes in multiple sclerosis pathogenesis.
Jack van Horssen;Maarten E. Witte;Gerty Schreibelt;Helga E. de Vries.
Biochimica et Biophysica Acta (2011)
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling
Gerty Schreibelt;Gijs Kooij;Arie Reijerkerk;Ruben van Doorn.
The FASEB Journal (2007)
Macrophages and neurodegeneration
Jerome J.A. Hendriks;Charlotte E. Teunissen;Helga E. de Vries;Christine D. Dijkstra.
Brain Research Reviews (2005)
Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?
Maarten E. Witte;Jeroen J.G. Geurts;Helga E. de Vries;Paul van der Valk.
Interferon-β directly influences monocyte infiltration into the central nervous system
Sarah Floris;Sigrid R. Ruuls;Anne Wierinckx;Susanne M.A. van der Pol.
Journal of Neuroimmunology (2002)
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