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Helga E. de Vries

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
20774
World Ranking
3211
National Ranking
81

Helga E. de Vries publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Helga E. de Vries sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 231 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Helga E. de Vries D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Helga E. de Vries sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 85 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Helga E. de Vries is affiliated with the University of Amsterdam in the Netherlands and has an extensive publication record in the fields of medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their research encompasses a range of subfields, including neurology, molecular biology, immunology, physiology, and pathology and forensic medicine.

Their work covers several main research topics, notably:

  • Neuroinflammation and neurodegeneration mechanisms
  • Multiple sclerosis research studies
  • Alzheimer's disease research and treatments
  • Sphingolipid metabolism and signaling
  • Barrier structure and function studies
  • Immune cell function and interaction
  • Neurogenesis and neuroplasticity mechanisms

Among their recent published papers are:

  • "Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages," 2020, Metabolites
  • "Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques," 2020, Nature Communications
  • "Inflammation of the choroid plexus in progressive multiple sclerosis: accumulation of granulocytes and T cells," 2020, Acta Neuropathologica Communications
  • "Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex," 2022, Nature Neuroscience
  • "Sphingolipids in Alzheimer's disease, how can we target them?", 2020, Advanced Drug Delivery Reviews

Frequent collaborators include Gijs Kooij, Alwin Kamermans, Carla Rodriguez-Mogeda, Susanne M. A. van der Pol, and Lynn van Olst, reflecting a collaborative research environment with multiple co-authored studies.

De Vries has published multiple times in prominent venues such as:

  • Journal of Neuroinflammation
  • Acta Neuropathologica Communications
  • Acta Neuropathologica
  • Fluids and Barriers of the CNS
  • Alzheimer's & Dementia

The diversity of publication venues illustrates de Vries's interdisciplinary approach, integrating knowledge from neuropathology, immunology, and neurodegenerative disease research. Their contributions span both basic and translational science, focusing on cellular and molecular mechanisms related to inflammation, immune response, and neurological disease processes.

Best Publications

  • The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

    Jorge Ivan Alvarez;Aurore Dodelet-Devillers;Hania Kebir;Igal Ifergan

  • The Blood-Brain Barrier in Neuroinflammatory Diseases

    Helga E. de Vries;Johan Kuiper;Albertus G. de Boer;Theo J. C. Van Berkel

  • Nrf2-induced antioxidant protection : A promising target to counteract ROS-mediated damage in neurodegenerative disease?

    Helga E. de Vries;Maarten Witte;David Hondius;Annemieke J.M. Rozemuller

  • Radical changes in multiple sclerosis pathogenesis.

    Jack van Horssen;Maarten E. Witte;Gerty Schreibelt;Helga E. de Vries

  • Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

    Gerty Schreibelt;Gijs Kooij;Arie Reijerkerk;Ruben van Doorn

  • The blood-brain barrier and its role in immune privilege in the central nervous system.

    Joel S Pachter;Helga E de Vries;Zsuzsa Fabry

  • Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?

    Maarten E. Witte;Jeroen J.G. Geurts;Helga E. de Vries;Paul van der Valk

  • Macrophages and neurodegeneration

    Jerome J.A. Hendriks;Charlotte E. Teunissen;Helga E. de Vries;Christine D. Dijkstra

  • Amyloid Beta Induces Oxidative Stress-Mediated Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy

    Anna Carrano;Jeroen J.M. Hoozemans;Saskia M. van der Vies;Annemieke J.M. Rozemuller

  • MicroRNA-155 negatively affects blood–brain barrier function during neuroinflammation

    Miguel Alejandro Lopez-Ramirez;Dongsheng Wu;Gareth Pryce;Julie E. Simpson

  • Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke.

    Melissa A. Lopes Pinheiro;Gijs Kooij;Mark R. Mizee;Alwin Kamermans

  • Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

    Pieter J. Gaillard;Chantal C. M. Appeldoorn;Rick Dorland;Joan van Kregten

  • Interferon-β directly influences monocyte infiltration into the central nervous system

    Sarah Floris;Sigrid R. Ruuls;Anne Wierinckx;Susanne M.A. van der Pol

  • Enhanced number and activity of mitochondria in multiple sclerosis lesions.

    Maarten E Witte;Lars Bø;Richard J Rodenburg;Jeroen A Belien

  • Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement.

    Machteld M. Vellinga;Raoul D. Oude Engberink;Alexandra Seewann;Petra J. W. Pouwels

  • The Blood-Brain Barrier in Cortical Multiple Sclerosis Lesions

    Jack van Horssen;Bianca P Brink;Helga E de Vries;Paul van der Valk

  • Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis.

    Jerome J.A. Hendriks;Jacqueline Alblas;Susanne M.A. van der Pol;Eric A.F. van Tol

  • Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis.

    Catharina M.P. Vos;Jeroen J.G. Geurts;Lisette Montagne;Elise S. van Haastert

  • Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation

    Erwin A. van Vliet;Grazia Forte;Linda Holtman;Jeroen C. G. den Burger

  • Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions.

    Ruben Van Doorn;Jack Van Horssen;Dennis Verzijl;Maarten Witte

Frequent Co-Authors

Jack van Horssen
Jack van Horssen Vrije Universiteit Amsterdam
Christine D. Dijkstra
Christine D. Dijkstra VU University Medical Center
Paul van der Valk
Paul van der Valk Vrije Universiteit Amsterdam
Sandra Amor
Sandra Amor University of Amsterdam
Ignacio A. Romero
Ignacio A. Romero The Open University
Dirk Geerts
Dirk Geerts University of Amsterdam
Gerty Schreibelt
Gerty Schreibelt Radboud University
Johan Kuiper
Johan Kuiper Leiden University
Theo J.C. Van Berkel
Theo J.C. Van Berkel Leiden University
Denis Vivien
Denis Vivien Université de Caen Normandie

External Links

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Best Scientists Citing Helga E. de Vries

Sandra Amor

Sandra Amor

University of Amsterdam

Publications: 47

Alexandre Prat

Alexandre Prat

University of Montreal

Publications: 43

Hans Lassmann

Hans Lassmann

Medical University of Vienna

Publications: 42

Britta Engelhardt

Britta Engelhardt

University of Bern

Publications: 37

Frederik Barkhof

Frederik Barkhof

University College London

Publications: 33

Eleonora Aronica

Eleonora Aronica

University of Amsterdam

Publications: 30

Jack van Horssen

Jack van Horssen

Vrije Universiteit Amsterdam

Publications: 29

Mária A. Deli

Mária A. Deli

Biological Research Centre

Publications: 28

V. Wee Yong

V. Wee Yong

University of Calgary

Publications: 27

Jeroen J. G. Geurts

Jeroen J. G. Geurts

Vrije Universiteit Amsterdam

Publications: 27

Pierre-Olivier Couraud

Pierre-Olivier Couraud

Inserm

Publications: 26

Francisco J. Quintana

Francisco J. Quintana

Harvard Medical School

Publications: 26

Niels Hellings

Niels Hellings

Hasselt University

Publications: 26

Eric V. Shusta

Eric V. Shusta

University of Wisconsin–Madison

Publications: 24

Ignacio A. Romero

Ignacio A. Romero

The Open University

Publications: 22

Paul van der Valk

Paul van der Valk

Vrije Universiteit Amsterdam

Publications: 22

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