World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
87
Citations
31642
World Ranking
1206
National Ranking
21

Medicine

D-Index
87
Citations
31739
World Ranking
13540
National Ranking
555

Overview

Alexandre Prat is affiliated with the University of Montreal in Canada and conducts research primarily in the field of Medicine. Their work spans several subfields including Pathology and Forensic Medicine, Neurology, Immunology, Molecular Biology, and Rheumatology.

The main topics covered in their research include:

  • Multiple Sclerosis Research Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Peripheral Neuropathies and Disorders
  • Rheumatoid Arthritis Research and Therapies
  • Polyomavirus and related diseases
  • COVID-19 Clinical Research Studies
  • Immunotherapy and Immune Responses

Prat has published extensively, with frequent appearances in publication venues such as:

  • Neurology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Multiple Sclerosis Journal
  • Neurology Neuroimmunology & Neuroinflammation
  • Multiple Sclerosis and Related Disorders

Representative publications by Alexandre Prat include:

  • MAFG-driven astrocytes promote CNS inflammation, 2020, Nature
  • Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study, 2020, The Lancet Neurology
  • Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes, 2021, Nature
  • Interpericyte tunnelling nanotubes regulate neurovascular coupling, 2020, Nature
  • Barcoded viral tracing of single-cell interactions in central nervous system inflammation, 2021, Science

The scientist frequently collaborates with other researchers, notably including:

  • Tomáš Kalinčík
  • Marc Girard
  • Pierre Duquette
  • Pierre Grammond
  • Dana Horáková

Best Publications

  • The Blood–Brain Barrier

    Richard Daneman;Alexandre Prat

  • Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation.

    Hania Kebir;Katharina Kreymborg;Igal Ifergan;Aurore Dodelet-Devillers

  • Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

    Veit Rothhammer;Ivan D Mascanfroni;Lukas Bunse;Maisa C Takenaka

  • The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

    Jorge Ivan Alvarez;Aurore Dodelet-Devillers;Hania Kebir;Igal Ifergan

  • An updated histological classification system for multiple sclerosis lesions

    Tanja Kuhlmann;Samuel Ludwin;Alexandre Prat;Jack Antel

  • Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

    Hania Kebir;Igal Ifergan;Jorge Ivan Alvarez;Monique Bernard

  • Glial influence on the blood brain barrier.

    Jorge Ivan Alvarez;Takahiro Katayama;Alexandre Prat

  • Association of Initial Disease-Modifying Therapy with Later Conversion to Secondary Progressive Multiple Sclerosis

    J. William L. Brown;J. William L. Brown;J. William L. Brown;Alasdair Coles;Dana Horakova;Eva Havrdova

  • Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

    Maisa C. Takenaka;Galina Gabriely;Veit Rothhammer;Ivan D. Mascanfroni

  • Brain-immune connection: immuno-regulatory properties of CNS-resident cells.

    Burkhard Becher;Alexandre Prat;Jack P. Antel

  • Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system

    Romain Cayrol;Karolina Wosik;Jennifer L Berard;Aurore Dodelet-Devillers

  • How do immune cells overcome the blood–brain barrier in multiple sclerosis?

    Catherine Larochelle;Jorge Ivan Alvarez;Alexandre Prat

  • Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.

    Lior Mayo;Sunia A Trauger;Manon Blain;Meghan Nadeau

  • MAFG-driven astrocytes promote CNS inflammation.

    Michael A. Wheeler;Iain C. Clark;Emily C. Tjon;Zhaorong Li

  • Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

    Rui Li;Ayman Rezk;Yusei Miyazaki;Ellen Hilgenberg

  • Defining secondary progressive multiple sclerosis.

    Johannes Lorscheider;Johannes Lorscheider;Katherine Buzzard;Katherine Buzzard;Katherine Buzzard;Vilija G Jokubaitis;Vilija G Jokubaitis;Tim Spelman

  • Glial cell influence on the human blood-brain barrier.

    Alexandre Prat;Katarzyna Biernacki;Karolina Wosik;Jack P. Antel

  • Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study.

    Anna He;Bernd Merkel;James William L Brown;James William L Brown;James William L Brown;Lana Zhovits Ryerson

  • Disruption of central nervous system barriers in multiple sclerosis

    Jorge Ivan Alvarez;Romain Cayrol;Alexandre Prat

  • Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10

    Olga L. Rojas;Anne-Katrin Pröbstel;Elisa A. Porfilio;Angela A. Wang

  • Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier

    Leslie L Muldoon;Jorge I Alvarez;David J Begley;Ruben J Boado

Frequent Co-Authors

Jack P. Antel
Jack P. Antel McGill University
Helmut Butzkueven
Helmut Butzkueven Monash University
Nathalie Arbour
Nathalie Arbour University of Montreal
Amit Bar-Or
Amit Bar-Or University of Pennsylvania
Eva Havrdova
Eva Havrdova Charles University
Maria Trojano
Maria Trojano University of Bari Aldo Moro
Raymond Hupperts
Raymond Hupperts Maastricht University
Francisco J. Quintana
Francisco J. Quintana Harvard Medical School
Burkhard Becher
Burkhard Becher University of Zurich
Alain Bouthillier
Alain Bouthillier University of Montreal

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Immunology in the USA opens doors to a variety of specialized healthcare roles, many of which can be advanced through targeted nursing degrees. For example, professionals may pursue the best pmhnp programs online to specialize as Psychiatric Mental Health Nurse Practitioners, blending immunology knowledge with mental health expertise.

Cost can be a significant factor when selecting a program. Thankfully, several cheap psych np programs offer quality education for those looking to advance without overspending.

As graduates move into advanced practice roles, understanding the compensation landscape is key. The doctor of nursing practice salary varies by state and specialty, making it important to align career goals with financial expectations.

For nurse practitioners wishing to pivot their focus, obtaining an acute care certification for fnp can facilitate a smooth transition to acute and specialized care settings, often incorporating immunology-related clinical work.

Best Scientists Citing Alexandre Prat

Trending Scientists