World's Best Scientists 2026 revealed!

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Immunology

D-Index
107
Citations
49723
World Ranking
541
National Ranking
12

Medicine

D-Index
107
Citations
49741
World Ranking
6171
National Ranking
83

Overview

Burkhard Becher is affiliated with the University of Zurich in Switzerland and has an extensive research portfolio primarily focused on immunology and microbiology, as well as medicine. Their work encompasses a range of subfields including immunology, oncology, neurology, molecular biology, and pathology and forensic medicine.

The scientist's research addresses several main topics, reflecting a diverse interest in immune system functions related to disease and therapeutic applications. Key topics include:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Cancer Immunotherapy and Biomarkers
  • Single-cell and spatial transcriptomics

Becher has contributed to multiple publications in various scientific venues. Notable recent papers include:

  • Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes, 2020, Cell
  • MAFG-driven astrocytes promote CNS inflammation, 2020, Nature
  • Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles, 2022, Science Immunology
  • Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development, 2020, Cell
  • Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes, 2021, Nature

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Science Immunology
  • Nature Communications
  • European Journal of Immunology

Collaborations form an important part of Becher's research output. Frequent co-authors include:

  • Nicolás Gonzalo Núñez
  • Florian Ingelfinger
  • Ekaterina Friebel
  • Donatella De Feo
  • Sònia Tugues

Best Publications

  • Immune attack: the role of inflammation in Alzheimer disease

    Frank L. Heppner;Richard M. Ransohoff;Burkhard Becher

  • Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation.

    Hania Kebir;Katharina Kreymborg;Igal Ifergan;Aurore Dodelet-Devillers

  • RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

    Laura Codarri;Gabor Gyülvészi;Vinko Tosevski;Lysann Hesske

  • C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

    Guillaume Hoeffel;Jinmiao Chen;Yonit Lavin;Donovan Low

  • NASH limits anti-tumour surveillance in immunotherapy-treated HCC

    Dominik Pfister;Dominik Pfister;Nicolás Gonzalo Núñez;Roser Pinyol;Olivier Govaere

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

    Melanie Greter;Frank L Heppner;Maria P Lemos;Bernhard M Odermatt

  • High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

    Dunja Mrdjen;Anto Pavlovic;Felix J. Hartmann;Bettina Schreiner

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

    Frank L Heppner;Melanie Greter;Denis Marino;Jeppe Falsig

  • High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy

    Carsten Krieg;Malgorzata Nowicka;Malgorzata Nowicka;Silvia Guglietta;Sabrina Schindler

  • Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

    Melanie Greter;Iva Lelios;Pawel Pelczar;Guillaume Hoeffel

  • Cytokine networks in neuroinflammation

    Burkhard Becher;Sabine Spath;Joan Goverman

  • IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells

    Margherita Coccia;Oliver J. Harrison;Chris Schiering;Chris Schiering;Mark J. Asquith

  • Innate lymphoid cells regulate intestinal epithelial cell glycosylation

    Yoshiyuki Goto;Takashi Obata;Jun Kunisawa;Shintaro Sato

  • Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles

    Unknown

  • APC-derived cytokines and T cell polarization in autoimmune inflammation.

    Ilona Gutcher;Burkhard Becher

  • Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes.

    Ekaterina Friebel;Konstantina Kapolou;Susanne Unger;Nicolás Gonzalo Núñez

  • GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation.

    Burkhard Becher;Sonia Tugues;Melanie Greter

  • Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12.

    Burkhard Becher;Brigit G. Durell;Randolph J. Noelle

  • Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

    Stanislav Pantelyushin;Stefan Haak;Barbara Ingold;Paulina Kulig

  • Experimental autoimmune encephalomyelitis repressed by microglial paralysis (vol 11, pg 146, 2005)

    FL Heppner;M Greter;D Marino;J Falsig

  • IL-1 mediates intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+Th17 cells

    M Coccia;O Harrison;C Schiering;M Asquith

Frequent Co-Authors

Melanie Greter
Melanie Greter University of Zurich
Jack P. Antel
Jack P. Antel McGill University
Ari Waisman
Ari Waisman Johannes Gutenberg University of Mainz
Mark D. Robinson
Mark D. Robinson University of Zurich
Marco Prinz
Marco Prinz University of Freiburg
Maries van den Broek
Maries van den Broek University of Zurich
Florent Ginhoux
Florent Ginhoux Agency for Science, Technology and Research
Alexandre Prat
Alexandre Prat University of Montreal
Thomas F. Lüscher
Thomas F. Lüscher University of Zurich
Christian Münz
Christian Münz University of Zurich

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