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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
31308
World Ranking
15876
National Ranking
292

Overview

Melanie Greter is affiliated with the University of Zurich in Switzerland and works primarily within the fields of Immunology and Microbiology, Neuroscience, and Medicine. Their research encompasses several interconnected areas, focusing on immune cells in cancer, neuroinflammation and neurodegeneration mechanisms, and immune response and inflammation. Additionally, they contribute to studies involving single-cell and spatial transcriptomics, immune cell function and interaction, T-cell and B-cell immunology, as well as immunotherapy and immune responses.

Their publication record includes significant research articles such as "Microglia states and nomenclature: A field at its crossroads" (2022, Neuron), "Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes" (2020, Cell), "Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development" (2020, Cell), "Pericytes regulate vascular immune homeostasis in the CNS" (2021, Proceedings of the National Academy of Sciences), and "IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation" (2022, Nature Immunology).

Frequent coauthors in their studies include Burkhard Becher, Florent Ginhoux, Sònia Tugues, Sebastian A. Stifter, and Sarah Mundt, with collaboration counts ranging from 11 to 26 publications respectively.

Their work is regularly published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Immunology, Cell Reports, Cell, and The Journal of Experimental Medicine. The highest number of publications have appeared in bioRxiv with nine contributions, followed by six in Nature Immunology.

The main topics of Melanie Greter's research span various aspects of immunology and neurobiology, addressing key questions about immune cell behavior in cancer environments and the mechanisms that drive inflammation and degeneration in the nervous system. Their approach often utilizes advanced molecular techniques to dissect immune responses and cellular interactions relevant to human disease.

  • Immune cells in cancer
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune Response and Inflammation
  • Single-cell and spatial transcriptomics
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses

  • Microglia states and nomenclature: A field at its crossroads (2022, Neuron)
  • Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes (2020, Cell)
  • Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development (2020, Cell)
  • Pericytes regulate vascular immune homeostasis in the CNS (2021, Proceedings of the National Academy of Sciences)
  • IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation (2022, Nature Immunology)

  • Burkhard Becher
  • Florent Ginhoux
  • Sònia Tugues
  • Sebastian A. Stifter
  • Sarah Mundt

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Cell Reports
  • Cell
  • The Journal of Experimental Medicine

Best Publications

  • Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

    Florent Ginhoux;Florent Ginhoux;Melanie Greter;Marylene Leboeuf;Sayan Nandi

  • Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

    Daigo Hashimoto;Andrew Chow;Andrew Chow;Clara Noizat;Clara Noizat;Pearline Teo

  • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

    Emmanuel L Gautier;Tal Shay;Tal Shay;Jennifer Miller;Melanie Greter

  • C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

    Guillaume Hoeffel;Jinmiao Chen;Yonit Lavin;Donovan Low

  • Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

    Melanie Greter;Frank L Heppner;Maria P Lemos;Bernhard M Odermatt

  • Origin of the lamina propria dendritic cell network.

    Milena Bogunovic;Florent Ginhoux;Julie Helft;Limin Shang

  • High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

    Dunja Mrdjen;Anto Pavlovic;Felix J. Hartmann;Bettina Schreiner

  • Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

    Guillaume Hoeffel;Yilin Wang;Melanie Greter;Peter See

  • Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

    Frank L Heppner;Melanie Greter;Denis Marino;Jeppe Falsig

  • The origin and development of nonlymphoid tissue CD103+ DCs

    Florent Ginhoux;Kang Liu;Julie Helft;Milena Bogunovic

  • Deciphering the transcriptional network of the dendritic cell lineage

    Jennifer C Miller;Brian D Brown;Tal Shay;Emmanuel L Gautier;Emmanuel L Gautier

  • Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

    Morgane Sonia Thion;Donovan Low;Aymeric Silvin;Jinmiao Chen

  • Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

    Melanie Greter;Iva Lelios;Pawel Pelczar;Guillaume Hoeffel

  • Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

    Kanako L. Lewis;Michele L. Caton;Milena Bogunovic;Melanie Greter

  • Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes.

    Ekaterina Friebel;Konstantina Kapolou;Susanne Unger;Nicolás Gonzalo Núñez

  • GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation.

    Burkhard Becher;Sonia Tugues;Melanie Greter

  • The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.

    Andrew L. Croxford;Margit Lanzinger;Felix J. Hartmann;Bettina Schreiner

  • Sall1 is a transcriptional regulator defining microglia identity and function

    Anne Buttgereit;Iva Lelios;Xueyang Yu;Melissa Vrohlings

  • GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

    Melanie Greter;Julie Helft;Andrew Chow;Daigo Hashimoto

  • Experimental autoimmune encephalomyelitis repressed by microglial paralysis (vol 11, pg 146, 2005)

    FL Heppner;M Greter;D Marino;J Falsig

Frequent Co-Authors

Burkhard Becher
Burkhard Becher University of Zurich
Florent Ginhoux
Florent Ginhoux Agency for Science, Technology and Research
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
E. Richard Stanley
E. Richard Stanley Albert Einstein College of Medicine
Adriano Aguzzi
Adriano Aguzzi University of Zurich
Claudia Jakubzick
Claudia Jakubzick Dartmouth College
Andreas Schlitzer
Andreas Schlitzer University of Bonn
Ari Waisman
Ari Waisman Johannes Gutenberg University of Mainz
Paul S. Frenette
Paul S. Frenette Albert Einstein College of Medicine

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