What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Signal transduction
Roger J. Daly mainly focuses on Cell biology, SH3 domain, SH2 domain, Receptor tyrosine kinase and GRB2.
As part of his studies on Cell biology, he often connects relevant areas like Receptor.
His SH3 domain study contributes to a more complete understanding of Biochemistry.
His SH2 domain research incorporates themes from Molecular biology, Insulin receptor substrate and Insulin Receptor Substrate Proteins.
The various areas that he examines in his Receptor tyrosine kinase study include Cancer research and Epidermal growth factor receptor.
Roger J. Daly works in the field of GRB2, focusing on GRB2 Adaptor Protein in particular.
His most cited work include:
- The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling (1382 citations)
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes (1304 citations)
- Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. (896 citations)
What are the main themes of his work throughout his whole career to date?
Roger J. Daly mainly investigates Cancer research, Cell biology, Signal transduction, Phosphorylation and Tyrosine phosphorylation.
Roger J. Daly has included themes like Carcinogenesis, Cancer, Cell growth, Tyrosine kinase and Receptor tyrosine kinase in his Cancer research study.
His work deals with themes such as Cortactin and Bioinformatics, which intersect with Cell biology.
His Signal transduction study integrates concerns from other disciplines, such as Receptor, Epidermal growth factor receptor and Endocrinology.
His Phosphorylation study incorporates themes from Molecular biology and Kinase.
His GRB2 research focuses on SH2 domain and how it relates to SH3 domain.
He most often published in these fields:
- Cancer research (50.48%)
- Cell biology (40.38%)
- Signal transduction (26.92%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (50.48%)
- Cell biology (40.38%)
- Phosphorylation (25.48%)
In recent papers he was focusing on the following fields of study:
Roger J. Daly focuses on Cancer research, Cell biology, Phosphorylation, Prostate cancer and Cell growth.
His study in Cancer research is interdisciplinary in nature, drawing from both Cancer cell, Cancer, Tumor microenvironment, Chemokine and Innate immune system.
His Cell biology research is multidisciplinary, incorporating elements of HEK 293 cells, Cell and Epidermal growth factor.
His Phosphorylation research includes themes of Tyrosine kinase and Kinase.
His biological study spans a wide range of topics, including Programmed cell death, Receptor, Glucocorticoid receptor and PI3K/AKT/mTOR pathway, PTEN.
His study explores the link between Tyrosine phosphorylation and topics such as Cell migration that cross with problems in Src family kinase, Motility, GRB2, Signalling and Function.
Between 2017 and 2021, his most popular works were:
- iFeature: a Python package and web server for features extraction and selection from protein and peptide sequences. (172 citations)
- Quokka: a comprehensive tool for rapid and accurate prediction of kinase family-specific phosphorylation sites in the human proteome. (89 citations)
- iLearn: an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data (83 citations)
In his most recent research, the most cited papers focused on:
Roger J. Daly mostly deals with Cancer research, Prostate cancer, Tumor microenvironment, Docetaxel and Proteome.
His Cancer research research integrates issues from Inflammation, Chemokine, Interleukin 8, Wound healing and Innate immune system.
His Prostate cancer research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Prostate, microRNA and Epigenome.
Roger J. Daly has researched Tumor microenvironment in several fields, including Bisulfite sequencing, Differentially methylated regions, DNA methylation, Gene expression profiling and Epigenetics.
His Docetaxel study combines topics from a wide range of disciplines, such as Taxane, Cabazitaxel, Apoptosis, Gene knockdown and Cancer cell.
His Proteome research incorporates elements of Extracellular matrix, Signal transduction, Cell biology, Cell adhesion and Cancer-Associated Fibroblasts.
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