World's Best Scientists 2026 revealed!
Steven E. Shoelson

Steven E. Shoelson

D-Index & Metrics

Biology and Biochemistry

D-Index
108
Citations
66870
World Ranking
1027
National Ranking
620

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Steven E. Shoelson is a researcher affiliated with Harvard University in the United States. Their work primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on topics related to phagocytosis and immune regulation, erythrocyte function and pathophysiology, cell death mechanisms and regulation, as well as advanced glycation end products research.

The scientist has published research addressing several interdisciplinary topics within molecular biology and clinical biochemistry. Their subfields of study include Immunology, Physiology, Molecular Biology, and Clinical Biochemistry.

Steven E. Shoelson's recent publications reflect a range of interests in cellular and molecular mechanisms. Two notable papers include:

  • "Externalized phosphatidylinositides on apoptotic cells are eat-me signals recognized by CD14," published in 2022 in Cell Death and Differentiation
  • "Retinal Not Systemic Oxidative and Inflammatory Stress Correlated with VEGF Expression in Rodent Models of Insulin Resistance and Diabetes," published in 2020 in UNC Libraries

Their research has appeared in venues such as Cell Death and Differentiation and UNC Libraries, which are among their more frequent publication platforms.

Steven E. Shoelson collaborates frequently with other researchers, including:

  • Jongsoon Lee
  • Ok-Hee Kim
  • Geun-Hyung Kang
  • June Hur
  • Jin Wook Lee

Among professional recognitions, the scientist is a member of the Association of American Physicians.

Best Publications

  • Inflammation and insulin resistance

    Steven E. Shoelson;Jongsoon Lee;Allison B. Goldfine

  • Type 2 diabetes as an inflammatory disease.

    Marc Y. Donath;Steven E. Shoelson

  • SH2 domains recognize specific phosphopeptide sequences

    Songyang Zhou;Songyang Zhou;Steven E. Shoelson;Manas Chaudhuri;Gerald Gish

  • Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB

    Dongsheng Cai;Minsheng Yuan;Daniel F Frantz;Daniel F Frantz;Peter A Melendez;Peter A Melendez

  • Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation

    Neil A. Farrow;Ranjith Muhandiram;Alex U. Singer;Steven M. Pascal

  • Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ

    Minsheng Yuan;Nicky Konstantopoulos;Jongsoon Lee;Lone Hansen

  • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

    Markus Feuerer;Laura Herrero;Laura Herrero;Daniela Cipolletta;Afia Naaz

  • Obesity, inflammation, and insulin resistance.

    Steven E. Shoelson;Laura Herrero;Afia Naaz

  • IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice

    Dongsheng Cai;J. Daniel Frantz;J. Daniel Frantz;Nicholas E. Tawa;Nicholas E. Tawa;Peter A. Melendez;Peter A. Melendez

  • Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.

    J M Backer;M G Myers;S E Shoelson;D J Chin

  • Phosphorylation of Ser307 in Insulin Receptor Substrate-1 Blocks Interactions with the Insulin Receptor and Inhibits Insulin Action

    Vincent Aguirre;Eric D. Werner;Jodel Giraud;Yong Hee Lee

  • Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

    Christian Bjørbæk;Joel K Elmquist;J.Daniel Frantz;Steven E Shoelson

  • PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue T reg cells

    Daniela Cipolletta;Markus Feuerer;Markus Feuerer;Amy Li;Nozomu Kamei;Nozomu Kamei

  • Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

    Z Songyang;S E Shoelson;J McGlade;P Olivier

  • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.

    Liangyou Rui;Minsheng Yuan;Daniel Frantz;Steven Shoelson

  • Crystal Structure of the Tyrosine Phosphatase SHP-2

    Peter Hof;Scott Pluskey;Sirano Dhe-Paganon;Michael J Eck

  • Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms

    Gabriel Waksman;Steven E. Shoelson;Nalin Pant;David Cowburn

  • Prevention of fat-induced insulin resistance by salicylate

    Jason K. Kim;Yoon-Jung Kim;Jonathan J. Fillmore;Yan Chen

  • Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

    Ripudaman S. Hundal;Kitt F. Petersen;Adam B. Mayerson;Pritpal S. Randhawa

  • Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

    Michael J. Eck;Steven E. Shoelson;Stephen C. Harrison;Stephen C. Harrison

Frequent Co-Authors

Allison B. Goldfine
Allison B. Goldfine Harvard University
Sirano Dhe-Paganon
Sirano Dhe-Paganon Harvard University
Michael J. Eck
Michael J. Eck Harvard University
Morris F. White
Morris F. White Boston Children's Hospital
Terrence R. Burke
Terrence R. Burke National Institutes of Health
Jonathan M. Backer
Jonathan M. Backer Albert Einstein College of Medicine
Stephen C. Harrison
Stephen C. Harrison Harvard University
Peter P. Roller
Peter P. Roller National Institutes of Health
Joseph Schlessinger
Joseph Schlessinger Yale University
Lewis C. Cantley
Lewis C. Cantley Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Biology or Biochemistry can open doors to many online study options and flexible career pathways in the health and life sciences sector. Many students interested in mental health may consider a fastest psych np program to quickly advance their qualifications as nurse practitioners specializing in psychiatric and mental health care.

For those focused on nutrition, an accelerated nutrition degree online combines core science knowledge with fast-track learning, enabling graduates to enter workforce roles like nutritionist or dietitian more efficiently. Biology and Biochemistry backgrounds also offer a solid foundation for health administration careers. An online healthcare mba is a practical option for those seeking leadership or management positions within medical organizations.

Alternative career paths include medical coding, where understanding of scientific terminology is valuable. If you’re deciding between professional certifications, comparing medical coding certification options can clarify differences, costs, and future salary prospects. No matter the path, online degrees and certifications offer flexibility, quicker completion times, and greater accessibility for students pursuing careers in health sciences.

Best Scientists Citing Steven E. Shoelson

Trending Scientists

Recently Published Articles