Pierre-Olivier Couraud mainly focuses on Blood–brain barrier, Cell biology, Endothelial stem cell, Neuroscience and Endothelium. His Blood–brain barrier research integrates issues from Caveolae, Biochemistry, Tight junction, Immunology and Molecular biology. The various areas that Pierre-Olivier Couraud examines in his Tight junction study include Signal transduction and Homeostasis.
His research in Cell biology intersects with topics in Aryl hydrocarbon receptor, Transcription factor and Gene expression. Pierre-Olivier Couraud has researched Endothelial stem cell in several fields, including Cadherin, Central nervous system and Immortalised cell line. His studies deal with areas such as Phenotype and Human brain as well as Central nervous system.
The scientist’s investigation covers issues in Cell biology, Blood–brain barrier, Endothelial stem cell, Immunology and In vitro. His Blood–brain barrier study combines topics from a wide range of disciplines, such as Molecular biology and Pharmacology. His biological study spans a wide range of topics, including Tumor necrosis factor alpha, Internal medicine, Endothelium, Human brain and Immortalised cell line.
His Immunology research incorporates themes from Cancer research and Drug delivery to the brain. Pierre-Olivier Couraud has included themes like Phenotype, Astrocyte and Pathology in his In vitro study. His Neuroscience study integrates concerns from other disciplines, such as Multiple sclerosis and Homeostasis.
Pierre-Olivier Couraud mostly deals with Blood–brain barrier, Cell biology, Endothelial stem cell, Immunology and Pharmacology. His Blood–brain barrier study is concerned with the larger field of Internal medicine. His Cell biology research is multidisciplinary, incorporating elements of Viability assay and Endocrinology.
His Endothelial stem cell study combines topics in areas such as Barrier function, Cell adhesion, Cell adhesion molecule and Small interfering RNA. His Immunology research incorporates elements of Vasculogenesis, Endothelium, Cellular differentiation and Cancer research. His Pharmacology research is multidisciplinary, incorporating perspectives in Oxidative stress, In vitro, Inflammation, Pathology and Brain ischemia.
Blood–brain barrier, Pharmacology, Immunology, Endothelial stem cell and Cell biology are his primary areas of study. His Blood–brain barrier research is multidisciplinary, relying on both Inflammation, Apolipoprotein E and Pathology. The study incorporates disciplines such as Transporter and Organic cation transport proteins in addition to Pharmacology.
His Immunology study integrates concerns from other disciplines, such as Cancer, Cancer stem cell and Drug resistance. His study in Endothelial stem cell is interdisciplinary in nature, drawing from both Oxidative stress, Cerebral infarction, Smoking cessation and Nicotine. His biological study deals with issues like Cellular differentiation, which deal with fields such as Progenitor cell, Phenotype, Notch signaling pathway and Cord blood.
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The blood-brain barrier in brain homeostasis and neurological diseases.
Nicolas Weiss;Florence Miller;Florence Miller;Sylvie Cazaubon;Sylvie Cazaubon;Pierre Olivier Couraud;Pierre Olivier Couraud.
Biochimica et Biophysica Acta (2009)
The hCMEC/D3 cell line as a model of the human blood brain barrier
Babette Barbash Weksler;Ignacio A. Romero;Pierre-Olivier Couraud;Pierre-Olivier Couraud;Pierre-Olivier Couraud.
Fluids and Barriers of the CNS (2013)
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation
Anny-Claude Luissint;Cédric Artus;Cédric Artus;Cédric Artus;Fabienne Glacial;Fabienne Glacial;Fabienne Glacial;Kayathiri Ganeshamoorthy;Kayathiri Ganeshamoorthy;Kayathiri Ganeshamoorthy.
Fluids and Barriers of the CNS (2012)
Puromycin-based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood-brain barrier-specific properties.
N Perriere;PH Demeuse;E Garcia;A Regina.
Journal of Neurochemistry (2005)
Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
Ramzi Shawahna;Yasuo Uchida;Xavier Declèves;Sumio Ohtsuki.
Molecular Pharmaceutics (2011)
ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.
Sandrine Dauchy;Sandrine Dauchy;Fabien Dutheil;Richard J. Weaver;Francine Chassoux.
Journal of Neurochemistry (2008)
The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies.
Birk Poller;Heike Gutmann;Stephan Krahenbuhl;Babette Weksler.
Journal of Neurochemistry (2008)
Differential effects of hydrocortisone and TNFα on tight junction proteins in an in vitro model of the human blood-brain barrier
Carola Förster;Malgorzata Burek;Ignacio A. Romero;Babette Weksler.
The Journal of Physiology (2008)
Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models
Kathryn Hatherell;Pierre-Olivier Couraud;Ignacio A. Romero;Babette Weksler.
Journal of Neuroscience Methods (2011)
Trans-inactivation of Receptor Tyrosine Kinases by Novel Angiotensin II AT2 Receptor-interacting Protein, ATIP *
Sandrine Nouet;Nathalie Amzallag;Jian-Mei Li;Simon Louis.
Journal of Biological Chemistry (2004)
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