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Sylvain G. Bourgoin

Sylvain G. Bourgoin

D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
6371
World Ranking
19004
National Ranking
665

Overview

Sylvain G. Bourgoin is affiliated with Université Laval in Canada and has contributed to research primarily within the fields of medicine, biochemistry, genetics, and molecular biology. Their work spans several subfields including immunology, molecular biology, physiology, hematology, and genetics.

The scientist's research focuses on several main topics related to immune function and blood physiology, including:

  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Erythrocyte Function and Pathophysiology
  • Phagocytosis and Immune Regulation
  • Platelet Disorders and Treatments
  • Extracellular vesicles in disease
  • Blood disorders and treatments
  • Immune Response and Inflammation

Bourgoin's recent papers reflect these topics, with publications in several peer-reviewed journals. Selected recent works include:

  • Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules (2021, Blood)
  • Phosphatidylserine-specific phospholipase A1: A friend or the devil in disguise (2021, Progress in Lipid Research)
  • Arf6 regulates energy metabolism in neutrophils (2021, Free Radical Biology and Medicine)
  • Metabolic regulation of neutrophil functions in homeostasis and diseases (2024, Journal of Leukocyte Biology)
  • Human Inflammatory Neutrophils Express Genes Encoding Peptidase Inhibitors: Production of Elafin Mediated by NF-κB and CCAAT/Enhancer-Binding Protein β (2021, The Journal of Immunology)

The scientist frequently publishes in the following venues:

  • Free Radical Biology and Medicine
  • International Journal of Molecular Sciences
  • Blood
  • Progress in Lipid Research
  • Journal of Leukocyte Biology

Bourgoin has collaborated extensively with several co-authors, with multiple joint publications. Key frequent collaborators include:

  • Stephan Hasse
  • Éric Boilard
  • Lynn Davis
  • Chenqi Zhao
  • Isabelle Allaeys

Best Publications

  • V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway

    Andrés Hurtado-Lorenzo;Mhairi Skinner;Jaafar El Annan;Masamitsu Futai

  • ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat

    Jia-Shu Yang;Stella Y. Lee;Minggeng Gao;Sylvain Bourgoin

  • Intracellular Localization of Phospholipase D1 in Mammalian Cells

    Zachary Freyberg;David Sweeney;Anirban Siddhanta;Sylvain Bourgoin

  • A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance.

    Jia Shu Yang;Helge Gad;Stella Y. Lee;Alexander Mironov

  • Peroxides of vanadate induce activation of phospholipase D in HL-60 cells. Role of tyrosine phosphorylation.

    S Bourgoin;S Grinstein

  • Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes.

    Bruno Maranda;Dennis Brown;Sylvain Bourgoin;James E. Casanova

  • Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils.

    Nicolas Flamand;Marc E. Surette;Serge Picard;Sylvain Bourgoin

  • Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils: interleukin-8, but not NAP-2 or GRO alpha, stimulates phospholipase D activity

    Gaέtan P. L'Heureux;Sylvain Bourgoin;Nathalie Jean;Shaun R. McColl

  • ACAP1 promotes endocytic recycling by recognizing recycling sorting signals

    Jun Dai;Jian Li;Erik Bos;Marimelia Porcionatto

  • Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils

    Marc Pouliot;Caroline Gilbert;Pierre Borgeat;Patrice E. Poubelle

  • Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1.

    Khalid Sendide;Neil E. Reiner;Jimmy S. I. Lee;Sylvain Bourgoin

  • Phospholipases D1 and D2 Coordinately Regulate Macrophage Phagocytosis

    Shankar S. Iyer;James A. Barton;Sylvain Bourgoin;David J. Kusner

  • Crystal-induced neutrophil activation VI. Involvement of FcγRIIIB (CD16) and CD11b in response to inflammatory microcrystals

    Frédéric Barabé;Caroline Gilbert;Nathalie Liao;Sylvain G. Bourgoin

  • Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2.

    Eric Boilard;Sylvain G. Bourgoin;Chantale Bernatchez;Marc E. Surette

  • Regulation of phospholipase D by phosphorylation-dependent mechanisms

    Martin G. Houle;Sylvain Bourgoin

  • ADP-ribosylation factor translocation correlates with potentiation of GTP gamma S-stimulated phospholipase D activity in membrane fractions of HL-60 cells.

    Martin G. Houle;Richard A. Kahn;Paul H. Naccache;Sylvain Bourgoin

  • Stimulation of Human Neutrophils by Chemotactic Factors Is Associated with the Activation of Phosphatidylinositol 3-Kinase γ

    Paul H. Naccache;Sylvain Levasseur;Geneviève Lachance;Sumone Chakravarti

  • The Mechanism of Docosahexaenoic Acid-induced Phospholipase D Activation in Human Lymphocytes Involves Exclusion of the Enzyme from Lipid Rafts

    Olivier Diaz;Alexandre Berquand;Madeleine Dubois;Silvia Di Agostino

  • V‐ATPase Interacts with ARNO and Arf6 in Early Endosomes and Regulates the Protein Degradative Pathway

    Andres Hurtado-Lorenzo;Mhairi Skinner;Jaafar El Annan;Masamitsu Futai

  • Short Article ACAP1 Promotes Endocytic Recycling by Recognizing Recycling Sorting Signals

    Jun Dai;Jian Li;Erik Bos;Marimelia Porcionatto

Frequent Co-Authors

Paul H. Naccache
Paul H. Naccache Université Laval
Pierre Borgeat
Pierre Borgeat Université Laval
Eric Boilard
Eric Boilard Université Laval
Shaun R. McColl
Shaun R. McColl University of Adelaide
Dennis A. Ausiello
Dennis A. Ausiello Harvard University
Victor W. Hsu
Victor W. Hsu Brigham and Women's Hospital
Dennis Brown
Dennis Brown Harvard University
Yasunori Kanaho
Yasunori Kanaho University of Tsukuba
David N. Brindley
David N. Brindley University of Alberta
Michael A. Frohman
Michael A. Frohman Stony Brook University

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