D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 7,802 122 World Ranking 6368 National Ranking 225

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Signal transduction

His primary scientific interests are in Biochemistry, Cell biology, Signal transduction, Tyrosine phosphorylation and Inflammation. Calcium is closely connected to Leukotriene B4 in his research, which is encompassed under the umbrella topic of Biochemistry. His research in Cell biology intersects with topics in Respiratory burst, GTP' and Cytochalasin.

His Signal transduction research is multidisciplinary, relying on both Cyclooxygenase and Superoxide. Paul H. Naccache interconnects Tyrosine kinase and Proto-oncogene tyrosine-protein kinase Src in the investigation of issues within Tyrosine phosphorylation. His Protein kinase A study combines topics from a wide range of disciplines, such as Molecular biology and Phorbol.

His most cited work include:

  • Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha. (225 citations)
  • Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils. (189 citations)
  • Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils. (165 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Biochemistry, Cell biology, Tyrosine phosphorylation, Leukotriene B4 and Phosphorylation. His studies in Biochemistry integrate themes in fields like Molecular biology and Calcium. His Cell biology research integrates issues from Receptor, Internal medicine, Endocrinology and Superoxide.

Paul H. Naccache combines subjects such as Tyrosine kinase, LYN, Proto-oncogene tyrosine-protein kinase Src, Syk and Phospholipase D with his study of Tyrosine phosphorylation. His Leukotriene B4 research includes themes of Mechanism of action, Arachidonic acid, Granulocyte macrophage colony-stimulating factor, Liberation and N-Formylmethionine leucyl-phenylalanine. His Phosphorylation research includes elements of Tyrosine and Nocodazole.

He most often published in these fields:

  • Biochemistry (59.09%)
  • Cell biology (34.85%)
  • Tyrosine phosphorylation (28.03%)

What were the highlights of his more recent work (between 2005-2020)?

  • Cell biology (34.85%)
  • Receptor (12.88%)
  • Biochemistry (59.09%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Receptor, Biochemistry, Tyrosine phosphorylation and Signal transduction. His Cell biology study frequently links to adjacent areas such as Molecular biology. Paul H. Naccache merges Biochemistry with Monosodium Urate Crystals in his study.

His Tyrosine phosphorylation study deals with the bigger picture of Phosphorylation. His work deals with themes such as Leukotriene B4, Superoxide and Polymorphonuclear neutrophil, which intersect with Chemotaxis. As part of one scientific family, Paul H. Naccache deals mainly with the area of Leukotriene B4, narrowing it down to issues related to the Pertussis toxin, and often Calcium.

Between 2005 and 2020, his most popular works were:

  • Up-Regulation of Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Endometriotic Cells by Macrophage Migration Inhibitory Factor: Involvement of Novel Kinase Signaling Pathways (77 citations)
  • Macrophage Migration Inhibitory Factor Elicits an Angiogenic Phenotype in Human Ectopic Endometrial Cells and Triggers the Production of Major Angiogenic Factors via CD44, CD74, and MAPK Signaling Pathways (58 citations)
  • Class IA Phosphatidylinositide 3-Kinases, rather than p110γ, Regulate Formyl-Methionyl-Leucyl-Phenylalanine-Stimulated Chemotaxis and Superoxide Production in Differentiated Neutrophil-Like PLB-985 Cells (41 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Signal transduction
  • Biochemistry

His main research concerns Cell biology, Signal transduction, Intracellular, Receptor and Neutrophil extracellular traps. As part of his studies on Cell biology, he often connects relevant areas like Biochemistry. His work in the fields of Biochemistry, such as Pi, Chemotaxis, PI3K/AKT/mTOR pathway and Superoxide, intersects with other areas such as Nucleofection.

His Signal transduction study combines topics in areas such as Proinflammatory cytokine, Prostaglandin E and Prostaglandin E2. The various areas that Paul H. Naccache examines in his Intracellular study include Phagocytosis, Immunology, Calcium metabolism, Calcium and Immunoglobulin G. Within one scientific family, he focuses on topics pertaining to Extracellular under Neutrophil extracellular traps, and may sometimes address concerns connected to Opsonin and Microbiology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha.

P A Tessier;P H Naccache;I Clark-Lewis;R P Gladue.
Journal of Immunology (1997)

342 Citations

Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.

J R White;C K Huang;J M Hill;P H Naccache.
Journal of Biological Chemistry (1984)

288 Citations

Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.

P H Naccache;T F Molski;P Borgeat;J R White.
Journal of Biological Chemistry (1985)

250 Citations

Granulocyte-Macrophage Colony-stimulating Factor-activated Signaling Pathways in Human Neutrophils SELECTIVE ACTIVATION OF Jak2, Stat3, AND Stat5B

Amin Al-Shami;Wahib Mahanna;Paul H. Naccache.
Journal of Biological Chemistry (1998)

227 Citations

Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

Mario Volpi;Paul H. Naccache;Thaddeus F. P. Molski;Jean Shefcyk.
Proceedings of the National Academy of Sciences of the United States of America (1985)

190 Citations

Characterization of the secretory activity of leukotriene B4 toward rabbit neutrophils.

H J Showell;P H Naccache;P Borgeat;S Picard.
Journal of Immunology (1982)

159 Citations

Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils: interleukin-8, but not NAP-2 or GRO alpha, stimulates phospholipase D activity

Gaέtan P. L'Heureux;Sylvain Bourgoin;Nathalie Jean;Shaun R. McColl.
Blood (1995)

154 Citations

Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha involves regulation at a post-cell surface receptor level. Enhancement of the effect of agents which directly activate G proteins.

S R McColl;D Beauseigle;C Gilbert;P H Naccache.
Journal of Immunology (1990)

153 Citations

Mono- and dihydroxyeicosatetraenoic acids alter calcium homeostasis in rabbit neutrophils.

P H Naccache;R I Sha'afi;P Borgeat;E J Goetzl.
Journal of Clinical Investigation (1981)

151 Citations

Involvement of tyrosine kinases in the activation of human peripheral blood neutrophils by granulocyte-macrophage colony-stimulating factor.

Shaun R. McColl;John F. DiPersio;Adriana C. Caon;Peggy Ho.
Blood (1991)

143 Citations

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