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Immunology

D-Index
85
Citations
27205
World Ranking
1313
National Ranking
48

Medicine

D-Index
85
Citations
27279
World Ranking
14579
National Ranking
554

Overview

Leo Koenderman is affiliated with Utrecht University in the Netherlands and has contributed extensively to medical and immunological research. Their work spans multiple subfields, including immunology, epidemiology, surgery, physiology, and pulmonary and respiratory medicine. The scientist's primary fields of study encompass Medicine and Immunology and Microbiology.

Their research covers several key topics:

  • Sepsis Diagnosis and Treatment
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Immune Response and Inflammation
  • Asthma and respiratory diseases
  • Immune cells in cancer
  • COVID-19 Clinical Research Studies
  • Exercise and Physiological Responses

Leo Koenderman has published papers in notable journals with multiple occurrences in:

  • Journal of Leukocyte Biology
  • European Journal of Trauma and Emergency Surgery
  • Frontiers in Immunology
  • Cellular and Molecular Immunology
  • Frontiers in Medicine

Among their recent publications are:

  • Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait (2020) in Thorax
  • On the origin of low-density neutrophils (2020) in Journal of Leukocyte Biology
  • Kinetics of Neutrophil Subsets in Acute, Subacute, and Chronic Inflammation (2021) in Frontiers in Immunology
  • Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) after Polytrauma: A Rare Syndrome with Major Consequences (2020) in Journal of Clinical Medicine
  • Cytokine receptor clustering in sensory neurons with an engineered cytokine fusion protein triggers unique pain resolution pathways (2021) in Proceedings of the National Academy of Sciences

Frequent collaborators include:

  • Nienke Vrisekoop
  • Falco Hietbrink
  • Roy Spijkerman
  • Bernard N. Jukema
  • Suzanne Bongers

This breadth of collaboration and publication across high-impact journals reflects ongoing engagement with contemporary issues in inflammation, immune cell behavior, trauma, and respiratory health.

Best Publications

  • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

    Pascale F Dijkers;Rene H Medema;Jan-Willem J Lammers;Leo Koenderman

  • In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.

    Janesh Pillay;Ineke den Braber;Nienke Vrisekoop;Lydia M. Kwast

  • A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

    Janesh Pillay;Vera M. Kamp;Els van Hoffen;Tjaakje Visser

  • The systemic immune response to trauma: an overview of pathophysiology and treatment.

    Janet M Lord;Mark J Midwinter;Yen-Fu Chen;Yen-Fu Chen;Antonio Belli

  • Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

    P.F. Dijkers;R.H. Medema;C. Pals;L. Banerji

  • Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.

    E. Caldenhoven;J. Liden;S. Wissink;A. Van de Stolpe

  • FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B–enhanced cell survival through maintenance of mitochondrial integrity

    Pascale F. Dijkers;Kim U. Birkenkamp;Eric W.-F. Lam;N. Shaun B. Thomas

  • Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences.

    Janesh Pillay;Tamar Tak;Vera M. Kamp;Leo Koenderman

  • Update on neutrophil function in severe inflammation

    Esmaeil Mortaz;Shamila D. Alipoor;Ian M. Adcock;Sharon Mumby

  • The Neutrophil Life Cycle

    Andrés Hidalgo;Andrés Hidalgo;Edwin R. Chilvers;Charlotte Summers;Leo Koenderman

  • 12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter.

    A. Van De Stolpe;E. Caldenhoven;B. G. Stade;L. Koenderman

  • The role of neutrophils in immune dysfunction during severe inflammation

    Pieter H. C. Leliefeld;Catharina M. Wessels;Luke P. H. Leenen;Leo Koenderman

  • What's your age again? Determination of human neutrophil half-lives revisited.

    Tamar Tak;Kiki Tesselaar;Janesh Pillay;José A. M. Borghans

  • Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes.

    Jacqueline Alblas;Laurien Ulfman;Peter Hordijk;Leo Koenderman

  • The role of STATs in myeloid differentiation and leukemia

    P J Coffer;L Koenderman;R P de Groot

  • Systemic inflammation in chronic obstructive pulmonary disease.

    E J D Oudijk;J W J Lammers;L Koenderman

  • Trauma: the role of the innate immune system

    F Hietbrink;L Koenderman;GT Rijkers;Lph Leenen

  • Modulation and induction of eosinophil chemotaxis by granulocyte- macrophage colony-stimulating factor and interleukin-3

    Ruud A.J. Warringa;Leo Koenderman;Paul T.M. Kok;Johannes Kreukniet

  • Regulation of Proliferation, Differentiation and Survival by the IL-3/IL-5/GM-CSF Receptor Family

    Rolf P. de Groot;Paul J. Coffer;Leo Koenderman

  • STAT5 Activation by BCR-Abl Contributes to Transformation of K562 Leukemia Cells

    Rolf P. de Groot;Jan A.M. Raaijmakers;Jan-Willem J. Lammers;Richard Jove

Frequent Co-Authors

Paul J. Coffer
Paul J. Coffer Utrecht University
Dirkje S. Postma
Dirkje S. Postma University Medical Center Groningen
Arthur J. Verhoeven
Arthur J. Verhoeven University of Amsterdam
Peter Pickkers
Peter Pickkers Radboud University
Dirk Roos
Dirk Roos University of Amsterdam
Gerard H. Koppelman
Gerard H. Koppelman University Medical Center Groningen
Anke-Hilse Maitland-van der Zee
Anke-Hilse Maitland-van der Zee University of Amsterdam
Jaap Jan Zwaginga
Jaap Jan Zwaginga Leiden University Medical Center
Peter D. Siersema
Peter D. Siersema Radboud University
Johannes G. Kusters
Johannes G. Kusters Utrecht University

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