H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Chemistry D-index 41 Citations 6,039 135 World Ranking 12188 National Ranking 3328
Biology and Biochemistry D-index 42 Citations 6,449 106 World Ranking 14903 National Ranking 6218

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Amino acid

Bhupendra P. Doctor mainly investigates Acetylcholinesterase, Biochemistry, Enzyme, Stereochemistry and Butyrylcholinesterase. His Acetylcholinesterase study combines topics from a wide range of disciplines, such as Pharmacology, Cholinesterase and Fetal bovine serum. In his study, which falls under the umbrella issue of Pharmacology, Toxicity and Antidote is strongly linked to Soman.

His Toxicity research includes elements of In vivo and Nerve agent. In general Stereochemistry study, his work on Moiety often relates to the realm of Edrophonium, thereby connecting several areas of interest. His Huperzine A research incorporates themes from Glutamate receptor, Enzyme inhibitor and Neuroprotection.

His most cited work include:

  • Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins (507 citations)
  • Stable Complexes Involving Acetylcholinesterase and Amyloid-β Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer’s Fibrils (239 citations)
  • Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase (162 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Acetylcholinesterase, Biochemistry, Pharmacology, Butyrylcholinesterase and Nerve agent. His Acetylcholinesterase study integrates concerns from other disciplines, such as Stereochemistry and Cholinesterase. Bhupendra P. Doctor has included themes like Molecular biology and Monoclonal antibody in his Biochemistry study.

His Pharmacology research is multidisciplinary, incorporating perspectives in Organophosphate poisoning, Atropine, Soman and Toxicity. His research investigates the connection between Butyrylcholinesterase and topics such as Pharmacokinetics that intersect with issues in Antibody. His research integrates issues of Sarin, Toxicology, Internal medicine, Acetylcholine and Inhalation exposure in his study of Nerve agent.

He most often published in these fields:

  • Acetylcholinesterase (48.70%)
  • Biochemistry (33.48%)
  • Pharmacology (31.74%)

What were the highlights of his more recent work (between 2006-2015)?

  • Nerve agent (23.48%)
  • Pharmacology (31.74%)
  • Butyrylcholinesterase (29.13%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Nerve agent, Pharmacology, Butyrylcholinesterase, Soman and Toxicity. His Nerve agent research includes elements of Sarin, Paraoxonase, Inhalation exposure and Internal medicine. His Pharmacology research incorporates themes from Acetylcholinesterase, Aché, Cytoplasm and Ligand.

The concepts of his Acetylcholinesterase study are interwoven with issues in Whole blood and Cholinesterase. His Butyrylcholinesterase study falls within the topics of Biochemistry and Enzyme. His work investigates the relationship between Soman and topics such as Median lethal dose that intersect with problems in Hematology.

Between 2006 and 2015, his most popular works were:

  • Prophylaxis with human serum butyrylcholinesterase protects guinea pigs exposed to multiple lethal doses of soman or VX (85 citations)
  • Advantages of the WRAIR whole blood cholinesterase assay: Comparative analysis to the micro-Ellman, Test-mate ChE™, and Michel (ΔpH) assays (52 citations)
  • [+]-Huperzine A treatment protects against N-methyl-D-aspartate-induced seizure/status epilepticus in rats. (44 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Amino acid

His scientific interests lie mostly in Butyrylcholinesterase, Nerve agent, Pharmacology, Soman and Sarin. His Butyrylcholinesterase research is multidisciplinary, relying on both Chromatography and In vivo. In Nerve agent, he works on issues like Toxicity, which are connected to Cell culture and Lethal dose.

His Pharmacology research integrates issues from Excitotoxicity, Inhalation exposure and Huperzine A. His Soman study combines Biochemistry and Acetylcholinesterase studies. His biological study spans a wide range of topics, including NMDA receptor, Neurotoxicity, Glutamate receptor and Cholinesterase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins

Miroslaw Cygler;Joseph D. Schrag;Joel L. Sussman;Michal Harel.
Protein Science (1993)

698 Citations

Stable Complexes Involving Acetylcholinesterase and Amyloid-β Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer’s Fibrils

Alejandra Alvarez;Rodrigo Alarcón;Carlos Opazo;Eliseo O. Campos.
The Journal of Neuroscience (1998)

386 Citations

Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase

Ashima Saxena;Ann M.G. Redman;Xuliang Jiang;Oksana Lockridge.
Biochemistry (1997)

305 Citations

Bioscavengers for the protection of humans against organophosphate toxicity.

Bhupendra P. Doctor;Ashima Saxena.
Chemico-Biological Interactions (2005)

223 Citations

Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos-oxon.

Gabriel Amitai;Gabriel Amitai;Deborah Moorad;Rachel Adani;B.P. Doctor.
Biochemical Pharmacology (1998)

206 Citations

Enzymes of the cholinesterase family

Daniel M. Quinn;A. S. Balasubramanian;Bhupendra P. Doctor;Palmer Taylor.
(1995)

190 Citations

Mechanism of inhibition of cholinesterases by huperzine A.

Yacov Ashani;Yacov Ashani;James O. Peggins;James O. Peggins;Bhupendra P. Doctor;Bhupendra P. Doctor.
Biochemical and Biophysical Research Communications (1992)

181 Citations

Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.

Haresh S. Ved;Michael L. Koenig;Jitendra R. Dave;Bhupendra P. Doctor.
Neuroreport (1997)

177 Citations

Enzymes as pretreatment drugs for organophosphate toxicity

Bhupendra P. Doctor;Lily Raveh;Alan D. Wolfe;Donald M. Maxwell.
Neuroscience & Biobehavioral Reviews (1991)

170 Citations

Acetylcholinesterase prophylaxis against organophosphate toxicity

A. D. Wolfe;R. S. Rush;B. P. Doctor;I. Koplovitz.
Toxicological Sciences (1987)

149 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Bhupendra P. Doctor

Patrick Masson

Patrick Masson

Kazan Federal University

Publications: 99

Oksana Lockridge

Oksana Lockridge

University of Nebraska Medical Center

Publications: 81

Kamil Kuca

Kamil Kuca

University of Hradec Králové

Publications: 68

Franz Worek

Franz Worek

Ludwig-Maximilians-Universität München

Publications: 63

Palmer Taylor

Palmer Taylor

University of Montana

Publications: 58

Joel L. Sussman

Joel L. Sussman

Weizmann Institute of Science

Publications: 57

Israel Silman

Israel Silman

Weizmann Institute of Science

Publications: 51

Horst Thiermann

Horst Thiermann

Ludwig-Maximilians-Universität München

Publications: 51

Florian Nachon

Florian Nachon

Centre national de la recherche scientifique, CNRS

Publications: 47

Stephen Brimijoin

Stephen Brimijoin

Mayo Clinic

Publications: 40

Nibaldo C. Inestrosa

Nibaldo C. Inestrosa

Pontificia Universidad Católica de Chile

Publications: 36

Hermona Soreq

Hermona Soreq

Hebrew University of Jerusalem

Publications: 33

Avigdor Shafferman

Avigdor Shafferman

Israel Institute for Biological Research

Publications: 30

Jean Massoulié

Jean Massoulié

École Normale Supérieure

Publications: 23

Baruch Velan

Baruch Velan

Sheba Medical Center

Publications: 23

Suzanne Bon

Suzanne Bon

École Normale Supérieure

Publications: 18

Something went wrong. Please try again later.