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Stephen Brimijoin

Stephen Brimijoin

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10383
World Ranking
13969
National Ranking
5899

Overview

Stephen Brimijoin is affiliated with the Mayo Clinic in the United States and works in multiple scientific disciplines including medicine, psychology, and biochemistry, genetics, and molecular biology. Their research spans across specialized subfields such as pharmacology, clinical psychology, and biotechnology.

The scientist's research topics include:

  • Cholinesterase and Neurodegenerative Diseases
  • Psychedelics and Drug Studies
  • Transgenic Plants and Applications

Stephen Brimijoin has contributed to the body of knowledge with publications in journals like Progress in Neuro-Psychopharmacology and Biological Psychiatry. One notable recent paper from 2020 is "A plant-derived cocaine hydrolase prevents cocaine overdose lethality and attenuates cocaine-induced drug seeking behavior," which examines biochemical and pharmacological strategies to counteract cocaine effects.

Coauthors collaborating frequently with Brimijoin include:

  • Katherine E. Larrimore
  • Latha Kannan
  • Robert Kendle
  • Tameem Jamal
  • Matthew Barcus

The combination of fields of study and topics reflects a multidisciplinary approach, integrating biochemical methods and molecular biology with clinical and psychological aspects of drug-related disorders and neurodegenerative conditions.

Best Publications

  • Highly Potent, Selective, and Low Cost Bis-tetrahydroaminacrine Inhibitors of Acetylcholinesterase STEPS TOWARD NOVEL DRUGS FOR TREATING ALZHEIMER'S DISEASE

    Yuan Ping Pang;Polly Quiram;Tanya Jelacic;Feng Hong

  • Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse.

    Bin Li;Judith A. Stribley;Judith A. Stribley;Andreea Ticu;Weihua Xie

  • Axonal transport of substance P in the vagus and sciatic nerves of the guinea pig

    Stephen Brimijoin;Stephen Brimijoin;Jan M. Lundberg;Jan M. Lundberg;Ernst Brodin;Ernst Brodin;Tomas Ho¨kfelt;Tomas Ho¨kfelt

  • Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex.

    T Rees;P.I Hammond;H Soreq;S Younkin

  • Molecular forms of acetylcholinesterase in brain, nerve and muscle: nature, localization and dynamics

    S. Brimijoin

  • Neurally Mediated Increase in Dopamine-β-Hydroxylase Activity

    Perry B. Molinoff;Steven Brimijoin;Richard Weinshilboum;Julius Axelrod

  • Retrograde axonal transport of transmitter enzymes, fucose-labeled protein, and nerve growth factor in streptozotocin-diabetic rats.

    Johannes Jakobsen;Stephen Brimijoin;Kenneth Skau;Per Sidenius

  • 1,25-Dihydroxyvitamin D3 receptors in the central nervous system of the rat embryo

    Timothy D Veenstra;Kirsten Prüfer;Carol Koenigsberger;Stephen W Brimijoin

  • Re-engineering butyrylcholinesterase as a cocaine hydrolase

    Hong Sun;Yuan Ping Pang;Oksana Lockridge;Stephen Brimijoin

  • The role of acetylcholinesterase in the pathogenesis of Alzheimer's disease.

    Tina M. Rees;Stephen Brimijoin

  • Neurite Differentiation Is Modulated in Neuroblastoma Cells Engineered for Altered Acetylcholinesterase Expression

    C. Koenigsberger;S. Chiappa;S. Brimijoin

  • Antipeptide antibodies confirm the topology of the human norepinephrine transporter

    Michael Brüss;Rainer Hammermann;Stephen Brimijoin;Heinz Bönisch

  • A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats.

    Stephen Brimijoin;Yang Gao;Justin J Anker;Luke A Gliddon

  • Peripheral peptide neurons: distribution, axonal transport, and some aspects on possible function.

    Lundberg Jm;Hökfelt T;Anggård A;Uvnäs-Wallensten K

  • Cholinesterases in neural development: new findings and toxicologic implications.

    Stephen Brimijoin;Carol Koenigsberger

  • Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase.

    Hong Sun;Maryann L. Shen;Maryann L. Shen;Yuan Ping Pang;Yuan Ping Pang;Oksana Lockridge

  • Ischemic conduction failure and energy metabolism in experimental diabetic neuropathy.

    P. A. Low;K. Ward;J. D. Schmelzer;S. Brimijoin

  • Rational Design of Alkylene-Linked Bis-Pyridiniumaldoximes as Improved Acetylcholinesterase Reactivators

    Yuan Ping Pang;Thomas M. Kollmeyer;Feng Hong;Jong Cheol Lee

  • Cholinesterases and the fine line between poison and remedy

    Carey N. Pope;Stephen Brimijoin

  • Stop‐flow: A new technique for measuring axonal transport, and its application to the transport of dopamine‐β‐hydroxylase

    Stephen Brimijoin

Frequent Co-Authors

Yuan Ping Pang
Yuan Ping Pang Mayo Clinic
Robin J. Parks
Robin J. Parks Ottawa Hospital
Vanda A. Lennon
Vanda A. Lennon Mayo Clinic
Oksana Lockridge
Oksana Lockridge University of Nebraska Medical Center
Marilyn E. Carroll
Marilyn E. Carroll University of Minnesota
Chang-Guo Zhan
Chang-Guo Zhan University of Kentucky
Thomas R. Kosten
Thomas R. Kosten Baylor College of Medicine
Peter J. Dyck
Peter J. Dyck Mayo Clinic
Carey Pope
Carey Pope Texas A&M University

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