David R. Tomlinson

Best Publications

• Glucose neurotoxicity

  Unknown

  545
  Citations

• A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy

  Tertia Purves;Alicia Middlemas;Sithiporn Agthong;Edward B. Jude

  355
  Citations

• A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats.

  Marzia Malcangio;David R Tomlinson

  311
  Citations

• Aldose reductase inhibitors and their potential for the treatment of diabetic complications

  David R. Tomlinson;Elizabeth J. Stevens;Lara T. Diemel

  246
  Citations

• Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy

  Paul Fernyhough;Alex Gallagher;Sharon A. Averill;John V. Priestley

  222
  Citations

• Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes

  Beatriz Duran-Jimenez;Darin Dobler;Sarah Moffatt;Naila Rabbani

  217
  Citations

• Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

  Tze Jen Huang;Sally A. Price;Lucy Chilton;Nigel A. Calcutt

  212
  Citations

• Diabetic neuropathy, nerve growth factor and other neurotrophic factors.

  Wendy J. Brewster;Paul Fernyhough;Lara T. Diemel;Liza Mohiuddin

  199
  Citations

• Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones

  Paul Fernyhough;Gary B. Willars;Ronald M. Lindsay;David R. Tomlinson

  192
  Citations

• A vitamin D3 derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats

  S. Riaz;M. Malcangio;M. Miller;D. R. Tomlinson

  174
  Citations

• Mitogen-Activated Protein Kinase p38 Mediates Reduced Nerve Conduction Velocity in Experimental Diabetic Neuropathy: Interactions With Aldose Reductase

  Sally A. Price;Sithiporn Agthong;Alicia B. Middlemas;David R. Tomlinson

  168
  Citations

• Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor☆

  Lara T. Diemel;Wendy J. Brewster;Paul Fernyhough;David R. Tomlinson

  163
  Citations

• Altered Neurotrophin mRNA Levels in Peripheral Nerve and Skeletal Muscle of Experimentally Diabetic Rats

  Paul Fernyhough;Lara T. Diemel;Wendy J. Brewster;David R. Tomlinson

  156
  Citations

• Nerve Growth Factor- and Neurotrophin-3-Induced Changes in Nociceptive Threshold and the Release of Substance P from the Rat Isolated Spinal Cord

  Marzia Malcangio;Neil E. Garrett;Simon Cruwys;David R. Tomlinson

  156
  Citations

• Aldose reductase inhibitors and diabetic complications

  David R. Tomlinson;Gary B. Willars;Anne L. Carrington

  152
  Citations

• α7 integrin mediates neurite outgrowth of distinct populations of adult sensory neurons

  Natalie J. Gardiner;Paul Fernyhough;David R. Tomlinson;Ulrike Mayer

  148
  Citations

• A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy.

  L. Hounsom;D. F. Horrobin;H. Tritschler;R. Corder

  140
  Citations

• Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor messenger RNA in streptozotocin-diabetic rats: Effects of insulin treatment

  P. Fernyhough;L.T. Diemel;W.J. Brewster;D.R. Tomlinson

  139
  Citations

• Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids.

  Ç. Karasu;M. Dewhurst;E. J. Stevens;D. R. Tomlinson

  135
  Citations

• Prevention and Reversal of Defective Axonal Transport and Motor Nerve Conduction Velocity In Rats with Experimental Diabetes by Treatment with the Aldose Reductase Inhibitor Sorbinil

  Unknown

  134
  Citations