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Neuroscience

D-Index
66
Citations
11782
World Ranking
3051
National Ranking
1412

Overview

Nigel A. Calcutt is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on medicine, with a significant concentration on physiology, neurology, molecular biology, cellular and molecular neuroscience, and pharmacology.

The scientist's work covers several key topics, including:

  • Pain Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Musculoskeletal Pain and Rehabilitation
  • Metabolism, Diabetes, and Cancer
  • Pain Management and Treatment
  • Adipose Tissue and Metabolism
  • Advancements in Transdermal Drug Delivery

They have contributed to multiple publications, particularly in these venues:

  • Diabetes & Metabolism Journal
  • Diagnostics
  • Nature
  • Pain
  • Proceedings of the National Academy of Sciences

Recent papers authored or co-authored by Nigel A. Calcutt include:

  • Diabetic neuropathy and neuropathic pain: a (con)fusion of pathogenic mechanisms?, 2020, Pain
  • Insulin-regulated serine and lipid metabolism drive peripheral neuropathy, 2023, Nature
  • Fecal transplantation and butyrate improve neuropathic pain, modify immune cell profile, and gene expression in the PNS of obese mice, 2020, Proceedings of the National Academy of Sciences
  • Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system, 2020, Expert Review of Neurotherapeutics
  • Novel and Emerging Electrophysiological Biomarkers of Diabetic Neuropathy and Painful Diabetic Neuropathy, 2021, Clinical Therapeutics

The scientist collaborates frequently with several co-authors, among whom are:

  • Katie Frizzi
  • Paul Fernyhough
  • Corinne G. Jolivalt
  • Andrew Marshall
  • May Madi Han

Best Publications

  • Injury Type-Specific Calcium Channel α2δ-1 Subunit Up-Regulation in Rat Neuropathic Pain Models Correlates with Antiallodynic Effects of Gabapentin

    Z. D. Luo;N. A. Calcutt;E. S. Higuera;C. R. Valder

  • Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing.

    Camilla I. Svensson;Martin Marsala;Anna Westerlund;Nigel A. Calcutt

  • Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine.

    Nigel A Calcutt;Michael C Jorge;Tony L Yaksh;Sandra R Chaplan

  • Schwann cell interactions with axons and microvessels in diabetic neuropathy

    Nádia P. Gonçalves;Christian B. Vægter;Henning Andersen;Leif Østergaard

  • Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

    Subir K. Roy Chowdhury;Darrell R. Smith;Ali Saleh;Jason Schapansky

  • Spinal pharmacology of tactile allodynia in diabetic rats

    Nigel A. Calcutt;Sandra R. Chaplan

  • Potential mechanisms of neuropathic pain in diabetes

    Nigel A Calcutt

  • Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

    Tze Jen Huang;Sally A. Price;Lucy Chilton;Nigel A. Calcutt

  • Regulation of Expression of the Sensory Neuron-Specific Sodium Channel SNS in Inflammatory and Neuropathic Pain

    Kenji Okuse;Sandra R. Chaplan;Stephen B. McMahon;Z.David Luo

  • Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor

    N. A. Calcutt;J. D. Freshwater;A. P. Mizisin

  • Insulin-regulated serine and lipid metabolism drive peripheral neuropathy

    Unknown

  • NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth.

    Michael L. Garcia;Christian S. Lobsiger;Sameer B. Shah;Tom J. Deerinck

  • Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.

    Mala V. Rao;Michael L. Garcia;Yukio Miyazaki;Takahiro Gotow

  • Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch

    Annika B. Malmberg;Andrew P. Mizisin;Nigel A. Calcutt;Thorsten von Stein

  • Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction.

    Danling Gu;Lise Wogensen;Nigel A. Calcutt;Chunyao Xia

  • Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab)

    G J Biessels;V Bril;N A Calcutt;N E Cameron

  • Epidermal nerve fiber quantification in the assessment of diabetic neuropathy.

    Kristina K. Beiswenger;Nigel A. Calcutt;Andrew P. Mizisin

  • Local anesthetic-induced conduction block and nerve fiber injury in streptozotocin-diabetic rats.

    Michael W. Kalichman;Nigel A. Calcutt

  • Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters.

    Corinne G. Jolivalt;Corinne A. Lee;Khara M. Ramos;Nigel A. Calcutt

  • Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue.

    H Godridge;G P Reynolds;C Czudek;N A Calcutt

  • Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment

    Subir K. Roy Chowdhury;Elena Zherebitskaya;Darrell R. Smith;Eli Akude

Frequent Co-Authors

Paul Fernyhough
Paul Fernyhough University of Manitoba
Jeffrey L. Goldberg
Jeffrey L. Goldberg Stanford University
Ronald M. Lindsay
Ronald M. Lindsay Zebra Biologics (United States)
Gabriel Corfas
Gabriel Corfas University of Michigan–Ann Arbor
Scott Letendre
Scott Letendre University of California, San Diego
Howard S. Fox
Howard S. Fox University of Nebraska Medical Center
Armen N. Akopian
Armen N. Akopian The University of Texas Health Science Center at San Antonio

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