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Paul Fernyhough

Paul Fernyhough

D-Index & Metrics

Neuroscience

D-Index
60
Citations
9617
World Ranking
3914
National Ranking
226

Overview

Paul Fernyhough is affiliated with the University of Manitoba in Canada and has a research focus primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work predominantly lies within subfields such as Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Geriatrics and Gerontology, and Neurology.

The research topics covered by Fernyhough include:

  • Adipose Tissue and Metabolism
  • Pain Mechanisms and Treatments
  • Sirtuins and Resveratrol in Medicine
  • Ion channel regulation and function
  • Metabolism, Diabetes, and Cancer
  • Mitochondrial Function and Pathology
  • Neuroscience and Neuropharmacology Research

Fernyhough has contributed to several publication venues with multiple papers appearing in Molecular Neurobiology, Molecular Metabolism, International Journal of Molecular Sciences, and Alzheimer's & Dementia. They have also published in the American Journal of Physiology-Heart and Circulatory Physiology.

Among recent papers authored by Fernyhough or with their coauthors are:

  • Oxidized phosphatidylcholines trigger ferroptosis in cardiomyocytes during ischemia-reperfusion injury, 2021, American Journal of Physiology-Heart and Circulatory Physiology
  • Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system, 2020, Expert Review of Neurotherapeutics
  • Oxidative Stress and Mitochondrial Dysfunction Associated with Peripheral Neuropathy in Type 1 Diabetes, 2021, Antioxidants and Redox Signaling
  • Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer's Mice, 2020, Cells
  • Sex-Specific Effects of Chronic Creatine Supplementation on Hippocampal-Mediated Spatial Cognition in the 3xTg Mouse Model of Alzheimer's Disease, 2020, Nutrients

Frequent co-authors collaborating with Fernyhough include:

  • Mohamad-Reza Aghanoori
  • Nigel A. Calcutt
  • Benedict C. Albensi
  • Darrell R. Smith
  • Subir Roy Chowdhury

Best Publications

  • A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy

    Tertia Purves;Alicia Middlemas;Sithiporn Agthong;Edward B. Jude

  • Role of neurotrophins in diabetic neuropathy and treatment with nerve growth factors.

    D R Tomlinson;P Fernyhough;L T Diemel

  • Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling

    Rimpy Dhingra;Victoria Margulets;Subir Roy Chowdhury;James Thliveris

  • Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy

    Paul Fernyhough;Alex Gallagher;Sharon A. Averill;John V. Priestley

  • Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

    Subir K. Roy Chowdhury;Darrell R. Smith;Ali Saleh;Jason Schapansky

  • Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

    Tze Jen Huang;Sally A. Price;Lucy Chilton;Nigel A. Calcutt

  • Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C.

    F. L. Hall;P. Fernyhough;D. N. Ishii;Philip R Vulliet

  • Diabetic neuropathy, nerve growth factor and other neurotrophic factors.

    Wendy J. Brewster;Paul Fernyhough;Lara T. Diemel;Liza Mohiuddin

  • Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones

    Paul Fernyhough;Gary B. Willars;Ronald M. Lindsay;David R. Tomlinson

  • Mitochondrial dysfunction in diabetic neuropathy: a series of unfortunate metabolic events.

    Paul Fernyhough

  • The role of aberrant mitochondrial bioenergetics in diabetic neuropathy.

    Subir K. Roy Chowdhury;Darrell R. Smith;Paul Fernyhough

  • Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab)

    G J Biessels;V Bril;N A Calcutt;N E Cameron

  • Mitochondrial stress and the pathogenesis of diabetic neuropathy

    Paul Fernyhough;Subir K Roy Chowdhury;Robert E Schmidt

  • Diminished Superoxide Generation is Associated with Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons from Diabetic Rats

    Eli Akude;Elena Zherebitskaya;Subir K. Roy Chowdhury;Darrell R. Smith

  • Development of Selective Axonopathy in Adult Sensory Neurons Isolated from Diabetic Rats: Role of Glucose-induced Oxidative Stress

    Elena Zherebitskaya;Eli Akude;Darrell R. Smith;Paul Fernyhough

  • Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor☆

    Lara T. Diemel;Wendy J. Brewster;Paul Fernyhough;David R. Tomlinson

  • Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons

    Tze Jen Huang;Alex Verkhratsky;Paul Fernyhough;Paul Fernyhough;Paul Fernyhough

  • DISTAL DEGENERATIVE SENSORY NEUROPATHY IN A LONG TERM TYPE 2 DIABETES RAT MODEL

    Valentine Brussee;GuiFang Guo;YingYing Dong;Chu Cheng

  • Altered Neurotrophin mRNA Levels in Peripheral Nerve and Skeletal Muscle of Experimentally Diabetic Rats

    Paul Fernyhough;Lara T. Diemel;Wendy J. Brewster;David R. Tomlinson

  • Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment

    Subir K. Roy Chowdhury;Elena Zherebitskaya;Darrell R. Smith;Eli Akude

Frequent Co-Authors

Nigel A. Calcutt
Nigel A. Calcutt University of California, San Diego
John V. Priestley
John V. Priestley Queen Mary University of London
Alexei Verkhratsky
Alexei Verkhratsky University of Manchester
Peter Horton
Peter Horton University of Sheffield
Christine H. Foyer
Christine H. Foyer University of Birmingham
Eva L. Feldman
Eva L. Feldman University of Michigan–Ann Arbor
Marzia Malcangio
Marzia Malcangio King's College London
Tak Pan Wong
Tak Pan Wong McGill University
Ronald M. Lindsay
Ronald M. Lindsay Zebra Biologics (United States)

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