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D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
19331
World Ranking
4602
National Ranking
2237

John S. O'Brien publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John S. O'Brien sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 222 publications — 58th percentile

58% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John S. O'Brien D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John S. O'Brien sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 78 D-Index — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John S. O'Brien was affiliated with the University of California, San Diego in the United States. Their academic work focused primarily on the fields of biochemistry, genetics, and molecular biology, with a specific concentration in cell biology.

The main topics of their investigations involved endoplasmic reticulum stress and disease. This area of research was addressed in several studies where they explored the cellular mechanisms and pathological impacts related to the endoplasmic reticulum.

Among their recent scholarly contributions was the paper titled Mechanisms of Endoplasmic Reticulum Stress-Mediated Pathways to Apoptosis: Significance for Tumor therapy, published in 2025 within the Fortune Journal of Health Sciences. This publication focused on the pathways by which endoplasmic reticulum stress leads to apoptosis and considered the relevance of these mechanisms for tumor therapy.

Their collaborations involved several frequent co-authors including:

  • Abdulaziz M. Eshaq
  • Thomas W. Flanagan
  • Maher Albitar
  • Nouf Alshammari
  • Maroa Al Jaberi

Their scholarly work appeared predominantly in the Fortune Journal of Health Sciences, where they contributed at least one documented publication.

Best Publications

  • Lipid composition of the normal human brain: gray matter, white matter, and myelin

    John S. O'Brien;E. Lois Sampson

  • Tay-Sachs Disease: Generalized Absence of a Beta-D-N-Acetylhexosaminidase Component

    Shintaro Okada;John S. O'Brien

  • Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin

    John S. O'Brien;E. Lois Sampson

  • Tay-sachs disease. Detection of heterozygotes and homozygotes by serum hexosaminidase assay.

    John S. O'Brien;Shintaro Okada;Agnes Chen;Dorothy L. Fillerup

  • Generalized Gangliosidosis: Beta-Galactosidase Deficiency

    Shintaro Okada;John S. O'Brien

  • Saposin proteins: structure, function, and role in human lysosomal storage disorders.

    John S. O'Brien;Yasuo Kishimoto

  • Saposins: structure, function, distribution, and molecular genetics.

    Y Kishimoto;M Hiraiwa;J S O'Brien

  • Coding of two sphingolipid activator proteins (SAP-1 and SAP-2) by same genetic locus

    John S. O'Brien;Keith A. Kretz;Nazneen Dewji;David A. Wenger

  • Gaucher's disease: deficiency of 'acid' -glucosidase and reconstitution of enzyme activity in vitro.

    Mae Wan Ho;John S. O'Brien

  • Identification of prosaposin as a neurotrophic factor

    John S. O'Brien;Geoffrey S. Carson;Hee Chan Seo;Masao Hiraiwa

  • Stability of the Myelin Membrane

    John S. O'Brien

  • I-Cell Disease: Biochemical Studies

    Jules G Leroy;Mae Wan Ho;Monica C Macbrinn;Klaus Zielke

  • Cell membranes—Composition: Structure: Function

    John S. O'Brien

  • Cloning and expression of human arylsulfatase A.

    C. Stein;V. Gieselmann;J. Kreysing;B. Schmidt

  • Quantification and fatty acid and fatty aldehyde composition of ethanolamine, choline, and serine glycerophosphatides in human cerebral grey and white matter

    John S. O'Brien;John S. O'Brien;Dorothy L. Fillerup;Dorothy L. Fillerup;James F. Mead;James F. Mead

  • GENERALIZED GANGLIOSIDOSIS: ANOTHER INBORN ERROR OF GANGLIOSIDE METABOLISM?

    John S. O'brien;Maury B. Stern;Benjamin H. Landing;Joanne K. O'brien

  • Gm1 Ganglioside β-Galactosidase A PURIFICATION AND STUDIES OF THE ENZYME FROM HUMAN LIVER

    Anthony G.W. Norden;Linda L. Tennant;John S. O'Brien

  • Sanfilippo Syndrome: Profound Deficiency of Alpha-Acetylglucosaminidase Activity in Organs and Skin Fibroblasts from Type-B Patients

    John S. O'brien

  • Tay-Sachs Disease: Prenatal Diagnosis

    John S. O'Brien;Shintaro Okada;Dorothy L. Fillerup;M. Lois Veath

  • Synthesis of 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid and detection of skin fibroblast neuraminidase in normal humans and in sialidosis.

    Thomas G. Warner;John S. O'Brien

Frequent Co-Authors

Brian M. Martin
Brian M. Martin National Institutes of Health
W. Marie Campana
W. Marie Campana University of California, San Diego
Nigel A. Calcutt
Nigel A. Calcutt University of California, San Diego
Shintaro Okada
Shintaro Okada Osaka University
John M. Tomich
John M. Tomich Kansas State University
John A. Barranger
John A. Barranger University of Pittsburgh
David A. Wenger
David A. Wenger Thomas Jefferson University
Maurizio Sorice
Maurizio Sorice Sapienza University of Rome
Shoji Tsuji
Shoji Tsuji University of Tokyo

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