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Biology and Biochemistry

D-Index
69
Citations
15303
World Ranking
7484
National Ranking
3410

Overview

David A. Wenger is affiliated with Thomas Jefferson University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, focusing on subfields such as Physiology, Molecular Biology, Epidemiology, Genetics, and Cell Biology.

The main topics covered in Wenger's work include:

  • Lysosomal Storage Disorders Research
  • Trypanosoma species research and implications
  • Virus-based gene therapy research
  • Cellular transport and secretion
  • Erythrocyte Function and Pathophysiology
  • Autism Spectrum Disorder Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research

Wenger has published extensively in multiple venues, with frequent publications appearing in:

  • UNC Libraries
  • Bioimpacts
  • CHEST Journal
  • Prenatal Diagnosis
  • Molecular Genetics and Metabolism

Recent publications by Wenger and collaborators include:

  • "Lysosomal storage disease spectrum in nonimmune hydrops fetalis: a retrospective case control study," 2020, Prenatal Diagnosis
  • "Conditions for combining gene therapy with bone marrow transplantation in murine Krabbe disease," 2020, Bioimpacts
  • "Chemical mutagenesis of a GPCR ligand: Detoxifying 'inflammo-attraction' to direct therapeutic stem cell migration," 2020, Proceedings of the National Academy of Sciences
  • "Consensus recommendations for the classification and long-term follow up of infants who screen positive for Krabbe Disease," 2021, Molecular Genetics and Metabolism
  • "Advances in the Diagnosis and Treatment of Krabbe Disease," 2021, International Journal of Neonatal Screening

Frequent coauthors collaborating with Wenger include:

  • Paola Luzi
  • Andreas Fouras
  • Mohammad A. Rafi
  • Maria L. Escolar
  • Olivia Stephens

Best Publications

  • Transplantation of Umbilical-Cord Blood in Babies with Infantile Krabbe's Disease

    Maria L Escolar;Michele D Poe;James M Provenzale;Karen C Richards

  • Cord-blood transplants from unrelated donors in patients with Hurler's syndrome.

    Susan L. Staba;Maria L. Escolar;Michele Poe;Young Kim

  • A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

    Peter G. Pentchev;Marcella E. Comly;Howard S. Kruth;Marie T. Vanier

  • Hematopoietic Stem-Cell Transplantation in Globoid-Cell Leukodystrophy

    William Krivit;Elsa G. Shapiro;Charles Peters;John E. Wagner

  • Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.

    Jean Pyo Lee;Mylvaganam Jeyakumar;Rodolfo Gonzalez;Hiroto Takahashi

  • Coding of two sphingolipid activator proteins (SAP-1 and SAP-2) by same genetic locus

    John S. O'Brien;Keith A. Kretz;Nazneen Dewji;David A. Wenger

  • Niemann-Pick C1 Disease: Correlations between NPC1 Mutations, Levels of NPC1 Protein, and Phenotypes Emphasize the Functional Significance of the Putative Sterol-Sensing Domain and of the Cysteine-Rich Luminal Loop

    Gilles Millat;Christophe Marçais;Catherine Tomasetto;Karim Chikh

  • Molecular genetics of Krabbe disease (globoid cell leukodystrophy): diagnostic and clinical implications.

    David A. Wenger;Mohammad A. Rafi;Paola Luzi

  • Krabbe disease: genetic aspects and progress toward therapy.

    David A. Wenger;Mohammad A. Rafi;Paola Luzi;Jeffrey Datto

  • Niemann-Pick disease group C: clinical variability and diagnosis based on defective cholesterol esterification. A collaborative study on 70 patients.

    Marie T. Vanier;David A. Wenger;Marcella E. Comly;Robert Rousson

  • Niemann-Pick C1 disease: the I1061T substitution is a frequent mutant allele in patients of Western European descent and correlates with a classic juvenile phenotype.

    Gilles Millat;Christophe Marçais;Mohammad A. Rafi;Toshiyuki Yamamoto

  • Type C Niemann-Pick disease. Abnormal metabolism of low density lipoprotein in homozygous and heterozygous fibroblasts.

    H S Kruth;M E Comly;J D Butler;M T Vanier

  • Newborn screening for Krabbe disease: the New York State model.

    Patricia K. Duffner;Michele Caggana;Joseph J. Orsini;David A. Wenger

  • Cloning and expression of cDNA encoding human galactocerebrosidase, the enzyme deficient in globoid cell leukodystrophy.

    Yue Qun Chen;Mohammad A. Rafi;Gregory de Gala;David A. Wenger

  • Type C Niemann-Pick disease. A parallel loss of regulatory responses in both the uptake and esterification of low density lipoprotein-derived cholesterol in cultured fibroblasts.

    P. G. Pentchev;H. S. Kruth;M. E. Comly;J. D. Butler

  • Treatment of late infantile metachromatic leukodystrophy by bone marrow transplantation.

    W Krivit;E Shapiro;W Kennedy;M Lipton

  • Molecular genetics of metachromatic leukodystrophy

    V Gieselmann;J Zlotogora;A Harris;D A Wenger

  • Human β-Mannosidase Deficiency

    David A. Wenger;Eva Sujansky;Paul V. Fennessey;Jerry N. Thompson

  • Structure and organization of the human galactocerebrosidase (GALC) gene.

    Paola Luzi;Mohammad A. Rafi;David A. Wenger

  • Niemann-pick disease type C in neonatal cholestasis at a North American Center.

    Baruch Yerushalmi;Ronald J Sokol;Michael R Narkewicz;Debra Smith

Frequent Co-Authors

Marie T. Vanier
Marie T. Vanier Grenoble Alpes University
Joanne Kurtzberg
Joanne Kurtzberg Duke University
James M. Provenzale
James M. Provenzale Duke University
William Krivit
William Krivit University of Minnesota
Evan Y. Snyder
Evan Y. Snyder Discovery Institute
Peter G. Pentchev
Peter G. Pentchev National Institutes of Health
Volkmar Gieselmann
Volkmar Gieselmann University of Bonn
Dietrich Matern
Dietrich Matern Mayo Clinic
Steven U. Walkley
Steven U. Walkley Albert Einstein College of Medicine
Ralph S. Lachman
Ralph S. Lachman University of California, Los Angeles

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