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Biology and Biochemistry

D-Index
72
Citations
13219
World Ranking
6474
National Ranking
3013

Overview

Reuben Matalon is affiliated with The University of Texas Medical Branch at Galveston in the United States. Their research spans multiple fields of study within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed to 16 publications in medicine and 4 in biochemistry, genetics, and molecular biology, indicating a strong interdisciplinary approach to medical research.

Their subfields of study include radiology, nuclear medicine and imaging, physiology, surgery, rheumatology, and epidemiology. Publications show a focus on advanced imaging techniques and physiological investigations, matched by clinical interests in surgery and rheumatology, as well as epidemiological aspects.

Key research topics associated with Reuben Matalon encompass:

  • Advanced MRI Techniques and Applications
  • Tissue Engineering and Regenerative Medicine
  • Lysosomal Storage Disorders Research
  • Trypanosoma species research and implications
  • Calcium signaling and nucleotide metabolism
  • Neurological disorders and treatments
  • Fetal and Pediatric Neurological Disorders

They have coauthored frequently with several researchers, highlighting collaboration within their field. Frequent coauthors include Dena R. Matalon, Kimberlee Michals Matalon, Lizhao Feng, Jianfei Chao, and Erpo Tian.

Reuben Matalon has published in respected venues, mainly Advanced Science and iScience. Their recent papers include:

  • Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs, 2020, Advanced Science
  • Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene, 2022, iScience
  • Stem Cell Therapy: Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs (Adv. Sci. 23/2020), 2020, Advanced Science

The focus of these papers is on stem cell therapy and therapeutic development for Canavan disease, reflecting an emphasis on regenerative medicine and treatment of neurological disorders. This aligns with the broader topics of lysosomal storage disorders and fetal and pediatric neurological disorders covered in their work.

Best Publications

  • Aspartoacylase deficiency and N-acetylaspartic aciduria in patients with Canavan disease.

    Reuben Matalon;K. Michals;D. Sebesta;M. Deanching

  • Treatment of Inborn Errors of Urea Synthesis — Activation of Alternative Pathways of Waste Nitrogen Synthesis and Excretion

    Mark L. Batshaw;Saul Brusilow;Lewis Waber;Wim Blom

  • Cloning of the human aspartoacylase cDNA and a common missense mutation in Canavan disease.

    Rajinder Kaul;Guang Ping Gao;Kuppareddi Balamurugan;Reuben Matalon

  • Multiple Phenotypes in Phosphoglucomutase 1 Deficiency

    Laura C. Tegtmeyer;Stephan Rust;Monique van Scherpenzeel;Bobby G. Ng

  • Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease.

    Chikkathur N. Madhavarao;Peethambaran Arun;John R. Moffett;Sylvia Szucs

  • Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A

    Peter L. Rady;Sylvia Szucs;James Grady;S. David Hudnall

  • Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.

    Heidi Erlandsen;Angel L. Pey;Angel L. Pey;Alejandra Gámez;Belén Pérez

  • Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease.

    P. Leone;P. Leone;Christopher G Janson;Christopher G Janson;L. Bilianuk;Z. Wang

  • Hurler's syndrome: biosynthesis of acid mucopolysaccharides in tissue culture

    Reuben Matalon;Albert Dorfman

  • Canavan disease: mutations among Jewish and non-Jewish patients.

    Rajinder Kaul;Guang P. Gao;Maria Aloya;Kuppareddi Balamurugan

  • Characterization of mouse and human GTP cyclohydrolase I genes. Mutations in patients with GTP cyclohydrolase I deficiency.

    Hiroshi Ichinose;Tamae Ohye;Yoichi Matsuda;Tada Aki Hori

  • Knock-out mouse for Canavan disease: a model for gene transfer to the central nervous system

    Reuben Matalon;Peter L. Rady;Kenneth A. Platt;Henry B. Skinner

  • Morquio's syndrome: deficiency of a chondroitin sulfate N-acetylhexosamine sulfate sulfatase.

    Reuben Matalon;Bradley Arbogast;Parvin Justice;Ira K. Brandt

  • Intellectual development in 12-year-old children treated for phenylketonuria.

    Colleen G. Azen;Richard Koch;Eva Gross Friedman;Stanley Berlow

  • The Maternal Phenylketonuria International Study: 1984-2002.

    Richard Koch;William Hanley;Harvey Levy;Kim Matalon

  • Canavan disease: from spongy degeneration to molecular analysis

    Reuben Matalon;Kimberlee Michals;Rajinder Kaul

  • Hurler's syndrome, an a-L-iduronidase deficiency

    Reuben Matalon;Albert Dorfman

  • Ehlers-Danlos Syndrome Type VIIA and VIIB Result From Splice-Junction Mutations or Genomic Deletions That Involve Exon 6 in the COL1A1 and COL1A2 Genes of Type I Collagen

    Peter H. Byers;Madeleine Duvic;Mary Atkinson;Meinhard Robinow

  • The mucopolysaccharidoses (A review)

    Albert Dorfman;Reuben Matalon

  • Purification, characterization, and localization of aspartoacylase from bovine brain.

    Rajinder Kaul;Jose Casanova;Anne B. Johnson;Peter Tang

Frequent Co-Authors

Albert Dorfman
Albert Dorfman University of Chicago
Guangping Gao
Guangping Gao University of Massachusetts Chan Medical School
Stephen K. Tyring
Stephen K. Tyring The University of Texas Health Science Center at Houston
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Lawrence D. Platt
Lawrence D. Platt University of California, Los Angeles
Glyn Dawson
Glyn Dawson University of Chicago
Matthew J. During
Matthew J. During The Ohio State University
Elizabeth N. Allred
Elizabeth N. Allred Boston Children's Hospital
Sau Wai Cheung
Sau Wai Cheung Baylor College of Medicine
Pawel Stankiewicz
Pawel Stankiewicz Baylor College of Medicine

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