What is he best known for?
The fields of study he is best known for:
- Enzyme
- Gene
- Internal medicine
His primary scientific interests are in Biochemistry, Internal medicine, Endocrinology, Enzyme and Molecular biology.
His Ganglioside, Glycoprotein, Sphingomyelin, Glucocerebrosidase and Glycolipid investigations are all subjects of Biochemistry research.
He usually deals with Ganglioside and limits it to topics linked to Receptor and Cholera toxin.
His Internal medicine research focuses on Fabry disease, Enzyme replacement therapy and Prospective cohort study.
His Enzyme study integrates concerns from other disciplines, such as Hydrolysis and Metabolism.
His Molecular biology research incorporates elements of Enzyme assay, Immunocytochemistry, Cerebral cortex, Mutant and Antibody.
His most cited work include:
- d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor (901 citations)
- Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. (815 citations)
- METABOLISM OF GLUCOCEREBROSIDES. II. EVIDENCE OF AN ENZYMATIC DEFICIENCY IN GAUCHER'S DISEASE. (668 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Biochemistry, Internal medicine, Endocrinology, Molecular biology and Enzyme.
His study looks at the intersection of Biochemistry and topics like Myelin with Polyacrylamide gel electrophoresis.
His research in Enzyme replacement therapy, Fabry disease and Bone marrow are components of Internal medicine.
His Fabry disease research is multidisciplinary, incorporating perspectives in Vascular disease and Immunology.
Endocrinology is a component of his Cholesterol and Niemann–Pick disease studies.
In his research on the topic of Molecular biology, Antigen is strongly related with Antibody.
He most often published in these fields:
- Biochemistry (30.77%)
- Internal medicine (20.64%)
- Endocrinology (16.32%)
What were the highlights of his more recent work (between 2008-2021)?
- Bipolar disorder (13.70%)
- Neuroscience (12.20%)
- Schizophrenia (8.82%)
In recent papers he was focusing on the following fields of study:
Roscoe O. Brady mostly deals with Bipolar disorder, Neuroscience, Schizophrenia, Psychiatry and Mania.
His Bipolar disorder study combines topics from a wide range of disciplines, such as Mood, Anterior cingulate cortex, Schizoaffective disorder, Functional magnetic resonance imaging and Neuroimaging.
His Schizophrenia research includes themes of Psychosis, Cognition, Default mode network and Clinical psychology.
His Psychiatry research focuses on Resting state fMRI and how it relates to Brain mapping.
In his work, Dorsolateral prefrontal cortex is strongly intertwined with Amygdala, which is a subfield of Mania.
Internal medicine is closely connected to Pathology in his research, which is encompassed under the umbrella topic of Connectome.
Between 2008 and 2021, his most popular works were:
- Lysosomal alpha-galactosidase controls the generation of self lipid antigens for natural killer T cells. (104 citations)
- Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood–brain barrier (95 citations)
- Cerebellar-Prefrontal Network Connectivity and Negative Symptoms in Schizophrenia (72 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Internal medicine
Bipolar disorder, Neuroscience, Psychiatry, Mania and Default mode network are his primary areas of study.
His Bipolar disorder research is multidisciplinary, relying on both Anterior cingulate cortex, Schizoaffective disorder, Schizophrenia and Impulsivity.
The study incorporates disciplines such as Emotional dysregulation, Internal medicine, Amygdala and Cortex in addition to Anterior cingulate cortex.
His studies in Internal medicine integrate themes in fields like Clinical Global Impression and Surgery.
Roscoe O. Brady works mostly in the field of Schizoaffective disorder, limiting it down to concerns involving Connectomics and, occasionally, Pathology.
His research integrates issues of Resting state fMRI, Brain mapping and Mood in his study of Mania.
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