D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 49 Citations 7,875 143 World Ranking 13724 National Ranking 5790

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Genetics

Her primary areas of investigation include Biochemistry, Cell biology, NEU1, Galactosialidosis and Sialidosis. Her research in Cell biology intersects with topics in Apoptosis, Membrane protein and Tumor progression. Her NEU1 research includes themes of Sialic acid, Phenotype, Sarcoma, Cytoskeleton and Membrane glycoproteins.

Her research on Galactosialidosis concerns the broader Cathepsin A. As a member of one scientific family, she mostly works in the field of Cathepsin A, focusing on Glial fibrillary acidic protein and, on occasion, Transgene and Molecular biology. Her Sialidosis study incorporates themes from Exocytosis, Mannose 6-phosphate receptor and Cell membrane.

Her most cited work include:

  • GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis (199 citations)
  • E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation. (195 citations)
  • GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis. (186 citations)

What are the main themes of her work throughout her whole career to date?

Alessandra d'Azzo mostly deals with NEU1, Cell biology, Biochemistry, Cathepsin A and Molecular biology. Her studies deal with areas such as Sialidosis and Sialic acid as well as NEU1. Her Intracellular study, which is part of a larger body of work in Cell biology, is frequently linked to Exosome, bridging the gap between disciplines.

Alessandra d'Azzo studies Galactosialidosis which is a part of Cathepsin A. Her Galactosialidosis research integrates issues from Lysosome and Transgene. Her study looks at the intersection of Molecular biology and topics like GLB1 with Binding protein and Beta-galactosidase.

She most often published in these fields:

  • NEU1 (29.05%)
  • Cell biology (27.70%)
  • Biochemistry (24.32%)

What were the highlights of her more recent work (between 2016-2021)?

  • Cell biology (27.70%)
  • NEU1 (29.05%)
  • Sialidosis (19.59%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Cell biology, NEU1, Sialidosis, Lysosomal storage disease and Enzyme replacement therapy. Her Cell biology study integrates concerns from other disciplines, such as Carcinogenesis, Exocytosis, Epigenetics and Membrane protein. Her NEU1 research is multidisciplinary, incorporating perspectives in Optical coherence tomography and Bioinformatics.

Her Lysosomal storage disease research is multidisciplinary, incorporating perspectives in Cathepsin A, Neuraminidase and Cancer research. Alessandra d'Azzo studies Galactosialidosis, a branch of Cathepsin A. Her Enzyme study is associated with Biochemistry.

Between 2016 and 2021, her most popular works were:

  • Lysosomal storage diseases. (177 citations)
  • Mitochondria-associated ER membranes (MAMs) and lysosomal storage diseases (41 citations)
  • MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat. (21 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Genetics

Alessandra d'Azzo mainly focuses on Cell biology, Exosome, Cell signaling, NEU1 and Wnt signaling pathway. She combines Cell biology and Induced pluripotent stem cell in her research. Alessandra d'Azzo carries out multidisciplinary research, doing studies in Exosome and Lipid bilayer.

Combining a variety of fields, including Cell signaling, Connective tissue, Fibrosis and Sialidosis, are what the author presents in her essays. Alessandra d'Azzo has included themes like Extracellular, Vesicle and Tetraspanin in her Membrane protein study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation.

Alessandra d'Azzo;Antonella Bongiovanni;Tommaso Nastasi.
Traffic (2005)

301 Citations

GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.

Alessandra Tessitore;Maria del P. Martin;Renata Sano;Yanjun Ma.
Molecular Cell (2004)

295 Citations

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

Renata Sano;Ida Annunziata;Annette Patterson;Simon Moshiach.
Molecular Cell (2009)

278 Citations

Lysosomal storage diseases.

Frances M Platt;Alessandra d'Azzo;Beverly L Davidson;Beverly L Davidson;Elizabeth F Neufeld.
Nature Reviews Disease Primers (2018)

269 Citations

Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor

Ana Maria Cuervo;Linda Mann;Erik J. Bonten;Alessandra d'Azzo.
The EMBO Journal (2003)

229 Citations

Association of alpha- and beta-subunits during the biosynthesis of beta-hexosaminidase in cultured human fibroblasts.

R L Proia;A d'Azzo;E F Neufeld.
Journal of Biological Chemistry (1984)

218 Citations

Sialidases in Vertebrates : A Family Of Enzymes Tailored For Several Cell Functions*

Eugenio Monti;Erik Bonten;Alessandra D'Azzo;Roberto Bresciani.
Advances in Carbohydrate Chemistry and Biochemistry (2010)

182 Citations

Generalized CNS Disease and Massive GM1-Ganglioside Accumulation in Mice Defective in Lysosomal Acid β-galactosidase

Christopher N. Hahn;Maria del Pilar Martin;Maria Schröder;Marie T. Vanier.
Human Molecular Genetics (1997)

164 Citations

Neuraminidase 1 is a negative regulator of lysosomal exocytosis.

Gouri Yogalingam;Erik J. Bonten;Diantha van de Vlekkert;Huimin Hu.
Developmental Cell (2008)

161 Citations

Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A

Aarnoud van der Spoel;Erik Bonten;Alessandra d'Azzo.
The EMBO Journal (1998)

157 Citations

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