What is he best known for?
The fields of study he is best known for:
His main research concerns Virology, Virus, Genetic enhancement, Molecular biology and Viral vector.
His Virology study combines topics from a wide range of disciplines, such as Microvesicles, Plasmid and Transduction.
His work deals with themes such as Neuroscience research, Blood–brain barrier and Gene delivery, which intersect with Virus.
His Genetic enhancement research includes themes of Vector and Bioinformatics.
His Molecular biology study incorporates themes from Transgene, Gene silencing and Thymidine kinase, Herpes simplex virus.
His research integrates issues of Cancer research and Precursor cell in his study of Viral vector.
His most cited work include:
- Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers (3327 citations)
- Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits (337 citations)
- Depletion of GGA3 Stabilizes BACE and Enhances β-Secretase Activity (312 citations)
What are the main themes of his work throughout his whole career to date?
Genetic enhancement, Molecular biology, Virology, Gene delivery and Virus are his primary areas of study.
His Genetic enhancement research is multidisciplinary, incorporating perspectives in Cancer research, Vector, Adeno-associated virus, Pathology and Viral vector.
His Molecular biology study also includes fields such as
- Amplicon together with Bioluminescence imaging,
- Transgene that connect with fields like Cell biology.
His Cell biology study combines topics from a wide range of disciplines, such as Gene silencing, Gene expression and Huntingtin.
His Virology research includes themes of Plasmid, Transfection, Transduction and Recombinant DNA.
His studies examine the connections between Gene delivery and genetics, as well as such issues in Central nervous system, with regards to Sandhoff disease and Immunology.
He most often published in these fields:
- Genetic enhancement (39.55%)
- Molecular biology (23.73%)
- Virology (22.03%)
What were the highlights of his more recent work (between 2018-2021)?
- Recombinant DNA (9.60%)
- Virus (17.51%)
- Genetic enhancement (39.55%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Recombinant DNA, Virus, Genetic enhancement, Molecular biology and Virology.
His Virus research is multidisciplinary, relying on both Vector and Cell culture.
His Genetic enhancement research integrates issues from Systemic administration, Central nervous system, Ganglioside and Cell biology.
The Cell biology study which covers Transduction that intersects with Genetically modified mouse.
His work deals with themes such as Dopaminergic and Real-time polymerase chain reaction, which intersect with Molecular biology.
His research investigates the connection between Gene delivery and topics such as Spinal cord that intersect with problems in Lysosomal storage disease.
Between 2018 and 2021, his most popular works were:
- A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system. (30 citations)
- Selection of an Efficient AAV Vector for Robust CNS Transgene Expression. (24 citations)
- Ly6a Differential Expression in Blood-Brain Barrier Is Responsible for Strain Specific Central Nervous System Transduction Profile of AAV-PHP.B. (17 citations)
In his most recent research, the most cited papers focused on:
Miguel Sena-Esteves focuses on Genetic enhancement, Virus, Cell biology, Central nervous system and Recombinant DNA.
His Genetic enhancement research is mostly focused on the topic Gene delivery.
He combines subjects such as Plasmid, Glycogen storage disease type II, Glycogen, Vector and Genetically modified mouse with his study of Virus.
The concepts of his Cell biology study are interwoven with issues in Transgene, Gene silencing, Gene expression and Transduction.
His study in Central nervous system is interdisciplinary in nature, drawing from both Huntingtin, Messenger RNA and Small interfering RNA.
The Recombinant DNA study combines topics in areas such as Suspension culture, Transient transfection, Transfection, Virology and HEK 293 cells.
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