Huntingtin, Molecular biology, Huntingtin Protein, Huntington's disease and Cell biology are his primary areas of study. His Huntingtin research is multidisciplinary, incorporating perspectives in Small hairpin RNA, RNA interference, Gene silencing, Genetically modified mouse and Endosome. His Molecular biology study combines topics from a wide range of disciplines, such as Autophagy, Cytoplasm, Mutant protein, Mutant and Transcription.
The various areas that Neil Aronin examines in his Huntingtin Protein study include Vesicle, Polyglutamine tract and Trinucleotide repeat expansion. His Huntington's disease research is multidisciplinary, incorporating elements of Striatum and Neuroscience. His Cell biology study incorporates themes from Microvesicles, Proteome, Proteomics and Cell adhesion.
His scientific interests lie mostly in Huntingtin, Cell biology, Molecular biology, Huntington's disease and Internal medicine. Neil Aronin works on Huntingtin which deals in particular with Huntingtin Protein. His work in Huntingtin Protein covers topics such as Polyglutamine tract which are related to areas like SETD2.
Neil Aronin focuses mostly in the field of Cell biology, narrowing it down to topics relating to Microvesicles and, in certain cases, Mesenchymal stem cell. His Huntington's disease research includes elements of Striatum, Genetically modified mouse, Transgene and Neuroscience. His studies examine the connections between Internal medicine and genetics, as well as such issues in Endocrinology, with regards to Substance P and Neuropeptide.
His primary areas of investigation include Cell biology, Gene silencing, Small interfering RNA, Huntingtin and Huntington's disease. His studies deal with areas such as Oligonucleotide and Neuron as well as Cell biology. The Gene silencing study combines topics in areas such as Genetic enhancement, Pharmacology, In vivo and Kinase.
His Small interfering RNA study integrates concerns from other disciplines, such as Microvesicles, Vesicle, RNA interference and Central nervous system. His research on Huntingtin concerns the broader Mutant. His Huntington's disease study combines topics in areas such as Molecular biology, microRNA and Transgene.
His main research concerns Cell biology, Gene silencing, Small interfering RNA, In vivo and Central nervous system. The study incorporates disciplines such as Translation, RNA interference, Genetic enhancement and Kidney metabolism in addition to Cell biology. His research integrates issues of Olfactory bulb, Huntingtin, Molecular biology and Nasal administration in his study of Gene silencing.
He studies Huntingtin, namely Huntingtin Protein. His research investigates the connection with Small interfering RNA and areas like Microvesicles which intersect with concerns in Vesicle, Extracellular and Biophysics. His In vivo research is multidisciplinary, relying on both RNA-induced silencing complex and Phosphatase, Biochemistry, Kinase, Phosphorylation.
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Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain
Marian DiFiglia;Ellen Sapp;Kathryn O. Chase;Stephen W. Davies.
Science (1997)
Asymmetry in the assembly of the RNAi enzyme complex.
Dianne S. Schwarz;György Hutvágner;Tingting Du;Zuoshang Xu.
Cell (2003)
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons.
Marian DiFiglia;Ellen Sapp;Kathryn Chase;Cordula Schwarz.
Neuron (1995)
Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma
B. R. Seizinger;G. A. Rouleau;L. J. Ozelius;A. H. Lane.
Nature (1988)
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.
Kimberly B. Kegel;Manho Kim;Ellen Sapp;Charmian McIntyre.
The Journal of Neuroscience (2000)
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis
Yun J. Kim;Yong Yi;Ellen Sapp;Yumei Wang.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Early and progressive accumulation of reactive microglia in the Huntington disease brain.
E. Sapp;K. B. Kegel;N. Aronin;T. Hashikawa.
Journal of Neuropathology and Experimental Neurology (2001)
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy
E Martino;M Safran;F Aghini-Lombardi;R Rajatanavin.
Annals of Internal Medicine (1984)
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits
Marian DiFiglia;Miguel Sena-Esteves;Kathryn O. Chase;Ellen Sapp.
Proceedings of the National Academy of Sciences of the United States of America (2007)
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
Reka A. Haraszti;Marie-Cecile Didiot;Ellen Sapp;John D. Leszyk.
Journal of extracellular vesicles (2016)
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