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Giuseppe Campiani

Giuseppe Campiani

D-Index & Metrics

Chemistry

D-Index
53
Citations
9004
World Ranking
13185
National Ranking
444

Overview

Giuseppe Campiani is affiliated with the University of Siena in Italy and has contributed to various fields including Medicine and Biochemistry, Genetics, and Molecular Biology. Their work primarily focuses on subfields such as Molecular Biology, Organic Chemistry, Oncology, Pharmacology, and Plant Science.

Their research topics include Histone Deacetylase Inhibitors Research, Peptidase Inhibition and Analysis, Cannabis and Cannabinoid Research, Synthesis and Biological Activity, Protein Degradation and Inhibitors, Neuroscience and Neuropharmacology Research, and Retinal Development and Disorders.

Campiani has published in several frequent venues, with notable contributions in:

  • European Journal of Medicinal Chemistry
  • Molecules
  • Journal of Medicinal Chemistry
  • ACS Chemical Neuroscience
  • Archiv der Pharmazie

Significant recent papers include:

  • "Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists," 2020, Journal of Medicinal Chemistry
  • "Telomerase-based Cancer Therapeutics: A Review on their Clinical Trials," 2020, Current Topics in Medicinal Chemistry
  • "Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors," 2021, Journal of Medicinal Chemistry
  • "Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases," 2022, Molecules
  • "Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation," 2020, European Journal of Medicinal Chemistry

Frequent co-authors working with Campiani include Sandra Gemma, Stefania Butini, Gabriele Carullo, Simone Brogi, and Nicola Relitti. These collaborations reflect a multidisciplinary approach in research efforts.

Best Publications

  • Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.

    Sandra Gemma;Gagan Kukreja;Caterina Fattorusso;Marco Persico

  • Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease.

    Lhassane Ismaili;Bernard Refouvelet;Mohamed Benchekroun;Simone Brogi

  • Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77.

    Cristiano Ferlini;Lucia Cicchillitti;Giuseppina Raspaglio;Silvia Bartollino

  • Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors.

    Luisa Savini;Alessandra Gaeta;Caterina Fattorusso;Bruno Catalanotti

  • Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: Past, present, and future perspectives

    Giuseppe Campiani;Anna Ramunno;Giovanni Maga;Vito Nacci

  • Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies

    Giuseppe Campiani;E. Morelli;Sandra Gemma;Vito Nacci

  • The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.

    Cristiano Ferlini;Giuseppina Raspaglio;Simona Mozzetti;Lucia Cicchillitti

  • Thiazolothiazepine inhibitors of HIV-1 integrase

    Nouri Neamati;Jim A. Turpin;Heather E. Winslow;John L. Christensen

  • Identification of a more potent analogue of the naturally occurring alkaloid huperzine A. Predictive molecular modeling of its interaction with AChE

    Alan P. Kozikowski;Giuseppe Campiani;§ Li-Qiang Sun;Shaomeng Wang

  • Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent

    G Campiani;F Aiello;M Fabbrini;E Morelli

  • Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6.

    Margaret M Mc Gee;Edel Hyland;Giuseppe Campiani;Anna Ramunno

  • Synthesis, biological activity, and SARs of pyrrolobenzoxazepine derivatives, a new class of specific "peripheral-type" benzodiazepine receptor ligands.

    G Campiani;V Nacci;I Fiorini;M P De Filippis

  • A palladium-catalyzed route to huperzine A and its analogues and their anticholinesterase activity

    Giuseppe Campiani;Li Qiang Sun;Alan P. Kozikowski;Patricia Aagaard

  • Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.

    Stefano Federico;Luca Pozzetti;Alessandro Papa;Gabriele Carullo

  • Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases.

    Margherita Brindisi;A. Prasanth Saraswati;Simone Brogi;Sandra Gemma

  • Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663.

    Giovanni Maga;Sandra Gemma;Caterina Fattorusso;Giada A. Locatelli

  • Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation.

    Ming-Yu Wu;Gerard Esteban;Simone Brogi;Masahi Shionoya

  • Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.

    Giuseppe Campiani;Stefania Butini;Francesco Trotta;Caterina Fattorusso

  • Design, Synthesis, and Structure–Activity Relationship Studies of 4-Quinolinyl- and 9-Acrydinylhydrazones as Potent Antimalarial Agents

    Caterina Fattorusso;Giuseppe Campiani;Gagan Kukreja;Marco Persico

  • Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases.

    Samuele Maramai;Sandra Gemma;Simone Brogi;Giuseppe Campiani

  • Novel and highly potent 5-HT3 receptor agonists based on a pyrroloquinoxaline structure.

    Giuseppe Campiani;Andrea Cappelli;Vito Nacci;Maurizio Anzini

Frequent Co-Authors

Sandra Gemma
Sandra Gemma University of Siena
Ettore Novellino
Ettore Novellino University of Naples Federico II
Donatella Taramelli
Donatella Taramelli University of Milan
Mark Lawler
Mark Lawler Queen's University Belfast
Giovanni Maga
Giovanni Maga National Research Council (CNR)
Vanessa Yardley
Vanessa Yardley London School of Hygiene & Tropical Medicine
Maurizio Botta
Maurizio Botta University of Siena
Bhupendra P. Doctor
Bhupendra P. Doctor Walter Reed Army Institute of Research
Giuseppe Valacchi
Giuseppe Valacchi North Carolina State University
Alan P. Kozikowski
Alan P. Kozikowski StarWise Therapeutics LLC

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