Donatella Taramelli focuses on Plasmodium falciparum, Hemozoin, Stereochemistry, Biochemistry and Heme. Her Plasmodium falciparum study introduces a deeper knowledge of Malaria. Her studies deal with areas such as Tumor necrosis factor alpha, Biological activity, Chloroquine and Macrophage as well as Hemozoin.
Her studies in Stereochemistry integrate themes in fields like Chemical synthesis and Mechanism of action. Her Chemical synthesis research is multidisciplinary, incorporating perspectives in Molecular model, Antimalarial Agent and 4-Aminoquinoline. In her research, Cellular differentiation, Cell growth, HaCaT, Chemokine and Phagocyte is intimately related to Proinflammatory cytokine, which falls under the overarching field of Biochemistry.
Her scientific interests lie mostly in Plasmodium falciparum, In vitro, Biochemistry, Pharmacology and Stereochemistry. Her work on Plasmodium falciparum is being expanded to include thematically relevant topics such as Chloroquine. Donatella Taramelli combines subjects such as Cell culture, Molecular biology, In vivo and Microbiology with her study of In vitro.
As part of one scientific family, Donatella Taramelli deals mainly with the area of Stereochemistry, narrowing it down to issues related to the Combinatorial chemistry, and often Organic chemistry. Her Antimalarial Agent study combines topics in areas such as Pharmacophore and Ring. Donatella Taramelli interconnects Cancer research and Melanoma in the investigation of issues within Immunology.
Donatella Taramelli mainly focuses on Plasmodium falciparum, In vitro, Gametocyte, Artemisinin and Pharmacology. Her Plasmodium falciparum research includes themes of IC50, Chloroquine and Biochemistry. The various areas that she examines in her IC50 study include Traditional medicine and Stereochemistry.
The concepts of her In vitro study are interwoven with issues in Pharmacophore, Chemotype, Derivative, In silico and Computational biology. Her biological study spans a wide range of topics, including Plasmodium and Antimalarial Agent. She has included themes like Hemolysis, Antibiotics, In vitro toxicology, In vivo and Drug resistance in her Pharmacology study.
Plasmodium falciparum, Gametocyte, Combinatorial chemistry, Organic chemistry and Malaria are her primary areas of study. Her research integrates issues of Pharmacophore, Biochemistry and Pharmacology in her study of Plasmodium falciparum. Her Pharmacology research is multidisciplinary, relying on both Hemolysis, In vitro, Artemisinin, Dihydroartemisinin and Plasmodium berghei.
Her study in Gametocyte is interdisciplinary in nature, drawing from both Plasmodium and Antimalarial Agent. Donatella Taramelli interconnects Natural product, Semiquinone, Quinone and Biological activity in the investigation of issues within Combinatorial chemistry. Her Malaria research incorporates elements of Drug discovery and Virology.
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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong.
PLOS Pathogens (2016)
Structure−Activity Relationships in 4-Aminoquinoline Antiplasmodials. The Role of the Group at the 7-Position
Catherine H. Kaschula;Timothy J. Egan;Roger Hunter;Nicoletta Basilico.
Journal of Medicinal Chemistry (2002)
Inhibition of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins.
Laura Calabresi;Guido Franceschini;Cesare R. Sirtori;Anna De Palma.
Biochemical and Biophysical Research Communications (1997)
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
Sandra Gemma;Gagan Kukreja;Caterina Fattorusso;Marco Persico.
Bioorganic & Medicinal Chemistry Letters (2006)
Internalization of Aspergillus fumigatus conidia by epithelial and endothelial cells.
S Paris;E Boisvieux-Ulrich;B Crestani;O Houcine.
Infection and Immunity (1997)
Nitric Oxide–Mediated Induction of Ferritin Synthesis in J774 Macrophages by Inflammatory Cytokines: Role of Selective Iron Regulatory Protein-2 Downregulation
Stefania Recalcati;Donatella Taramelli;Dario Conte;Gaetano Cairo.
Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.
Christophe Biot;Donatella Taramelli;Isabelle Forfar-Bares;Lucien A. Maciejewski.
Molecular Pharmaceutics (2005)
Standardization of the Physicochemical Parameters to Assess in Vitro the β-Hematin Inhibitory Activity of Antimalarial Drugs
Silvia Parapini;Nicoletta Basilico;Erica Pasini;Timothy J Egan.
Experimental Parasitology (2000)
A microtitre-based method for measuring the haem polymerization inhibitory activity (HPIA) of antimalarial drugs.
Nicoletta Basilico;Elisabetta Pagani;Diego Monti;Piero Olliaro.
Journal of Antimicrobial Chemotherapy (1998)
Primary but not metastatic human melanomas expressing DR antigens stimulate autologous lymphocytes
Giuseppe Fossati;Donatella Taramelli;Andrea Balsari;Gordana Bogdanovich.
International Journal of Cancer (1984)
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