D-Index & Metrics Best Publications
Donatella Taramelli

Donatella Taramelli

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 6,436 152 World Ranking 12814 National Ranking 321

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Donatella Taramelli focuses on Plasmodium falciparum, Hemozoin, Stereochemistry, Biochemistry and Heme. Her Plasmodium falciparum study introduces a deeper knowledge of Malaria. Her studies deal with areas such as Tumor necrosis factor alpha, Biological activity, Chloroquine and Macrophage as well as Hemozoin.

Her studies in Stereochemistry integrate themes in fields like Chemical synthesis and Mechanism of action. Her Chemical synthesis research is multidisciplinary, incorporating perspectives in Molecular model, Antimalarial Agent and 4-Aminoquinoline. In her research, Cellular differentiation, Cell growth, HaCaT, Chemokine and Phagocyte is intimately related to Proinflammatory cytokine, which falls under the overarching field of Biochemistry.

Her most cited work include:

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. (257 citations)
  • Structure−Activity Relationships in 4-Aminoquinoline Antiplasmodials. The Role of the Group at the 7-Position (184 citations)
  • Inhibition of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins. (154 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Plasmodium falciparum, In vitro, Biochemistry, Pharmacology and Stereochemistry. Her work on Plasmodium falciparum is being expanded to include thematically relevant topics such as Chloroquine. Donatella Taramelli combines subjects such as Cell culture, Molecular biology, In vivo and Microbiology with her study of In vitro.

As part of one scientific family, Donatella Taramelli deals mainly with the area of Stereochemistry, narrowing it down to issues related to the Combinatorial chemistry, and often Organic chemistry. Her Antimalarial Agent study combines topics in areas such as Pharmacophore and Ring. Donatella Taramelli interconnects Cancer research and Melanoma in the investigation of issues within Immunology.

She most often published in these fields:

  • Plasmodium falciparum (30.68%)
  • In vitro (22.73%)
  • Biochemistry (19.70%)

What were the highlights of her more recent work (between 2014-2021)?

  • Plasmodium falciparum (30.68%)
  • In vitro (22.73%)
  • Gametocyte (5.30%)

In recent papers she was focusing on the following fields of study:

Donatella Taramelli mainly focuses on Plasmodium falciparum, In vitro, Gametocyte, Artemisinin and Pharmacology. Her Plasmodium falciparum research includes themes of IC50, Chloroquine and Biochemistry. The various areas that she examines in her IC50 study include Traditional medicine and Stereochemistry.

The concepts of her In vitro study are interwoven with issues in Pharmacophore, Chemotype, Derivative, In silico and Computational biology. Her biological study spans a wide range of topics, including Plasmodium and Antimalarial Agent. She has included themes like Hemolysis, Antibiotics, In vitro toxicology, In vivo and Drug resistance in her Pharmacology study.

Between 2014 and 2021, her most popular works were:

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. (257 citations)
  • HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes (58 citations)
  • cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. (43 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

Plasmodium falciparum, Gametocyte, Combinatorial chemistry, Organic chemistry and Malaria are her primary areas of study. Her research integrates issues of Pharmacophore, Biochemistry and Pharmacology in her study of Plasmodium falciparum. Her Pharmacology research is multidisciplinary, relying on both Hemolysis, In vitro, Artemisinin, Dihydroartemisinin and Plasmodium berghei.

Her study in Gametocyte is interdisciplinary in nature, drawing from both Plasmodium and Antimalarial Agent. Donatella Taramelli interconnects Natural product, Semiquinone, Quinone and Biological activity in the investigation of issues within Combinatorial chemistry. Her Malaria research incorporates elements of Drug discovery and Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong.
PLOS Pathogens (2016)

351 Citations

Structure−Activity Relationships in 4-Aminoquinoline Antiplasmodials. The Role of the Group at the 7-Position

Catherine H. Kaschula;Timothy J. Egan;Roger Hunter;Nicoletta Basilico.
Journal of Medicinal Chemistry (2002)

269 Citations

Inhibition of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins.

Laura Calabresi;Guido Franceschini;Cesare R. Sirtori;Anna De Palma.
Biochemical and Biophysical Research Communications (1997)

233 Citations

Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.

Sandra Gemma;Gagan Kukreja;Caterina Fattorusso;Marco Persico.
Bioorganic & Medicinal Chemistry Letters (2006)

214 Citations

Internalization of Aspergillus fumigatus conidia by epithelial and endothelial cells.

S Paris;E Boisvieux-Ulrich;B Crestani;O Houcine.
Infection and Immunity (1997)

185 Citations

Nitric Oxide–Mediated Induction of Ferritin Synthesis in J774 Macrophages by Inflammatory Cytokines: Role of Selective Iron Regulatory Protein-2 Downregulation

Stefania Recalcati;Donatella Taramelli;Dario Conte;Gaetano Cairo.
Blood (1998)

173 Citations

Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

Christophe Biot;Donatella Taramelli;Isabelle Forfar-Bares;Lucien A. Maciejewski.
Molecular Pharmaceutics (2005)

168 Citations

Standardization of the Physicochemical Parameters to Assess in Vitro the β-Hematin Inhibitory Activity of Antimalarial Drugs

Silvia Parapini;Nicoletta Basilico;Erica Pasini;Timothy J Egan.
Experimental Parasitology (2000)

151 Citations

A microtitre-based method for measuring the haem polymerization inhibitory activity (HPIA) of antimalarial drugs.

Nicoletta Basilico;Elisabetta Pagani;Diego Monti;Piero Olliaro.
Journal of Antimicrobial Chemotherapy (1998)

146 Citations

Primary but not metastatic human melanomas expressing DR antigens stimulate autologous lymphocytes

Giuseppe Fossati;Donatella Taramelli;Andrea Balsari;Gordana Bogdanovich.
International Journal of Cancer (1984)

139 Citations

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