World's Best Scientists 2026 revealed!
Sandra Gemma

Sandra Gemma

D-Index & Metrics

Chemistry

D-Index
44
Citations
5605
World Ranking
17017
National Ranking
664

Sandra Gemma publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Sandra Gemma sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 178 publications — 24th percentile

24% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Sandra Gemma D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sandra Gemma sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 44 D-Index — 7th percentile

7% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Sandra Gemma is affiliated with the University of Siena in Italy and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work is focused on several subfields including Molecular Biology, Organic Chemistry, Oncology, Epidemiology, and Pharmacology.

Their research spans a variety of topics, notably:

  • Histone Deacetylase Inhibitors Research
  • Peptidase Inhibition and Analysis
  • Cannabis and Cannabinoid Research
  • Synthesis and biological activity
  • Research on Leishmaniasis Studies
  • Click Chemistry and Applications
  • Neuroscience and Neuropharmacology Research

Notable recent papers authored or co-authored by Sandra Gemma include:

  • Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists, 2020, Journal of Medicinal Chemistry
  • Telomerase-based Cancer Therapeutics: A Review on their Clinical Trials, 2020, Current Topics in Medicinal Chemistry
  • Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors, 2021, Journal of Medicinal Chemistry
  • Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases, 2022, Molecules
  • Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation, 2020, European Journal of Medicinal Chemistry

Frequent publication venues for Sandra Gemma include:

  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry
  • Molecules
  • ACS Chemical Neuroscience
  • ChemMedChem

Collaborations have been established with recurring co-authors such as:

  • Giuseppe Campiani
  • Stefania Butini
  • Gabriele Carullo
  • Simone Brogi
  • Sara Rossi

Best Publications

  • β-Secretase as a Therapeutic Target for Alzheimer’s Disease

    Arun K. Ghosh;Sandra Gemma;Jordan Tang;Jordan Tang

  • Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.

    Sandra Gemma;Gagan Kukreja;Caterina Fattorusso;Marco Persico

  • Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.

    Arduino A. Mangoni;Catherine Guillou;Jean Jacques Vanden Eynde;Christopher Hulme

  • Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease.

    Lhassane Ismaili;Bernard Refouvelet;Mohamed Benchekroun;Simone Brogi

  • Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies

    Giuseppe Campiani;E. Morelli;Sandra Gemma;Vito Nacci

  • Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.

    Stefano Federico;Luca Pozzetti;Alessandro Papa;Gabriele Carullo

  • Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases.

    Margherita Brindisi;A. Prasanth Saraswati;Simone Brogi;Sandra Gemma

  • Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663.

    Giovanni Maga;Sandra Gemma;Caterina Fattorusso;Giada A. Locatelli

  • Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.

    Giuseppe Campiani;Stefania Butini;Francesco Trotta;Caterina Fattorusso

  • Design, Synthesis, and Structure–Activity Relationship Studies of 4-Quinolinyl- and 9-Acrydinylhydrazones as Potent Antimalarial Agents

    Caterina Fattorusso;Giuseppe Campiani;Gagan Kukreja;Marco Persico

  • Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases.

    Samuele Maramai;Sandra Gemma;Simone Brogi;Giuseppe Campiani

  • Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain

    Margherita Brindisi;Samuele Maramai;Sandra Gemma;Simone Brogi

  • Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior.

    Stefania Butini;Sandra Gemma;Giuseppe Campiani;Silvia Franceschini

  • Polypharmacology of dopamine receptor ligands

    Stefania Butini;K Nikolic;S Kassel;H Brückmann

  • Development of antitubercular compounds based on a 4-quinolylhydrazone scaffold. Further structure-activity relationship studies.

    Sandra Gemma;Luisa Savini;Maria Altarelli;Pierangela Tripaldi

  • Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials

    Sandra Gemma;Giuseppe Campiani;Stefania Butini;Bhupendra P. Joshi

  • Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors

    Stefania Butini;Giuseppe Campiani;Marianna Borriello;Sandra Gemma

  • Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents

    Sandra Gemma;Sandra Gemma;Caterina Camodeca;Caterina Camodeca;Margherita Brindisi;Margherita Brindisi;Simone Brogi;Simone Brogi

  • Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors†

    Giuseppe Campiani;Caterina Fattorusso;Stefania Butini;Alessandra Gaeta

  • Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.

    Giuseppe Campiani;Stefania Butini;Caterina Fattorusso;Bruno Catalanotti

  • Discovery of Huperzine A−Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Midgorge Recognition Sites

    Sandra Gemma;Emanuele Gabellieri;Paul Huleatt;Caterina Fattorusso

Frequent Co-Authors

Giuseppe Campiani
Giuseppe Campiani University of Siena
Ettore Novellino
Ettore Novellino University of Naples Federico II
Arun K. Ghosh
Arun K. Ghosh Purdue University West Lafayette
Donatella Taramelli
Donatella Taramelli University of Milan
Giovanni Maga
Giovanni Maga National Research Council (CNR)
Vanessa Yardley
Vanessa Yardley London School of Hygiene & Tropical Medicine
Giuseppe Valacchi
Giuseppe Valacchi North Carolina State University
Manfred Jung
Manfred Jung University of Freiburg
Lucia Altucci
Lucia Altucci University of Campania "Luigi Vanvitelli"
Ernesto Fattorusso
Ernesto Fattorusso University of Naples Federico II

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