Baruch Velan

Overview

Best Publications

• Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket.

  A Ordentlich;D Barak;C Kronman;Y Flashner

  438
  Citations

• Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

  Gitay Kryger;Michal Harel;Kurt Giles;Lilly Toker

  417
  Citations

• Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.

  Jane R. Parnes;Baruch Velan;Adam Felsenfeld;Lata Ramanathan

  372
  Citations

• Search for correlates of protective immunity conferred by anthrax vaccine.

  Shaul Reuveny;Moshe D. White;Yaakov Y. Adar;Yaron Kafri

  330
  Citations

• Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.

  A Shafferman;B Velan;A Ordentlich;C Kronman

  290
  Citations

• Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core.

  D. Barak;C. Kronman;A. Ordentlich;N. Ariel

  238
  Citations

• Aging of phosphylated human acetylcholinesterase: catalytic processes mediated by aromatic and polar residues of the active centre.

  Avigdor Shafferman;Arie Ordentlich;Dov Barak;Dana Stein

  234
  Citations

• Attenuated Nontoxinogenic and Nonencapsulated Recombinant Bacillus anthracis Spore Vaccines Protect against Anthrax

  S. Cohen;I. Mendelson;Z. Altboum;D. Kobiler

  217
  Citations

• Functional Characteristics of the Oxyanion Hole in Human Acetylcholinesterase

  Arie Ordentlich;Dov Barak;Chanoch Kronman;Naomi Ariel

  196
  Citations

• Multidisciplinary Approaches to Cholinesterase Functions

  Avigdor Shafferman;Baruch Velan

  182
  Citations

• Search for potential vaccine candidate open reading frames in the Bacillus anthracis virulence plasmid pXO1: in silico and in vitro screening.

  N. Ariel;A. Zvi;H. Grosfeld;O. Gat

  178
  Citations

• The Architecture of Human Acetylcholinesterase Active Center Probed by Interactions with Selected Organophosphate Inhibitors

  Arie Ordentlich;Dov Barak;Chanoch Kronman;Naomi Ariel

  163
  Citations

• Contribution of aromatic moieties of tyrosine 133 and of the anionic subsite tryptophan 86 to catalytic efficiency and allosteric modulation of acetylcholinesterase.

  Arie Ordentlich;Dov Barak;Chanoch Kronman;Naomi Ariel

  161
  Citations

• Genome-Based Bioinformatic Selection of Chromosomal Bacillus anthracis Putative Vaccine Candidates Coupled with Proteomic Identification of Surface-Associated Antigens

  N. Ariel;A. Zvi;K. S. Makarova;T. Chitlaru

  156
  Citations

• Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates.

  Yehuda Flashner;Emanuelle Mamroud;T. Avital Tidhar;Raphael Ber

  143
  Citations

• The effect of elimination of intersubunit disulfide bonds on the activity, assembly, and secretion of recombinant human acetylcholinesterase. Expression of acetylcholinesterase Cys-580----Ala mutant.

  B Velan;H Grosfeld;C Kronman;M Leitner

  139
  Citations

• N-glycosylation of human acetylcholinesterase: effects on activity, stability and biosynthesis

  B Velan;C Kronman;A Ordentlich;Y Flashner

  128
  Citations

• Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers.

  A. Ordentlich;D. Barak;C. Kronman;H.P. Benschop

  126
  Citations

• Production and secretion of high levels of recombinant human acetylcholinesterase in cultured cell lines: microheterogeneity of the catalytic subunit.

  Chanoch Kronman;Baruch Velan;Yehoshua Gozes;Moshe Leitner

  118
  Citations

• Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase.

  A Shafferman;A Ordentlich;D Barak;C Kronman

  118
  Citations