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D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
8145
World Ranking
18417
National Ranking
421

Overview

Ana C. Carrera is affiliated with the Spanish National Research Council in Spain. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on molecular biology and cancer research.

The scientist's recent published work includes:

  • Role of NRF2 in Lung Cancer, 2021, Cells
  • Targeting PTEN Regulation by Post Translational Modifications, 2022, Cancers
  • Towards the Search for Potential Biomarkers in Osteosarcoma: State-of-the-Art and Translational Expectations, 2022, International Journal of Molecular Sciences
  • Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL, 2021, Cells
  • A potential therapeutic strategy based on acute oxidative stress induction for wild-type NRF2/KEAP1 lung squamous cell carcinoma, 2024, Redox Biology

Their frequent co-authors include:

  • António Garrido
  • Miriam Sánchez-Ortega
  • Ana González-García
  • Carmen Hernández
  • Francisco Reina

Publications have appeared most often in the journals:

  • Cells
  • Cancers
  • International Journal of Molecular Sciences
  • Redox Biology
  • Stem Cell Reports

Ana C. Carrera's main fields of study encompass biochemistry, genetics, and molecular biology (14 publications), as well as medicine (13 publications). The subfields where their research is concentrated include molecular biology (12 publications), surgery (5 publications), cancer research (2 publications), immunology (2 publications), and oncology (2 publications).

The topics covered in their body of work include:

  • Genomics, phytochemicals, and oxidative stress
  • PI3K/AKT/mTOR signaling in cancer
  • Ubiquitin and proteasome pathways
  • Nitrogen and Sulfur Effects on Brassica
  • Glutathione Transferases and Polymorphisms
  • Protein Kinase Regulation and GTPase Signaling
  • Sarcoma Diagnosis and Treatment

Best Publications

  • PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

    Domingo F Barber;Almira Bartolomé;Carmen Hernandez;Juana M Flores

  • Forkhead transcription factors contribute to execution of the mitotic programme in mammals.

    Beatriz Alvarez;Carlos Martínez-A.;Boudewijn M. T. Burgering;Ana C. Carrera

  • Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase

    Concepción Jimenez;David R. Jones;Pablo Rodríguez‐Viciana;Ana Gonzalez‐García

  • Role of the PI3K regulatory subunit in the control of actin organization and cell migration.

    Concepción Jiménez;Rosario Armas Portela;Mario Mellado;Jose Miguel Rodríguez-Frade

  • Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis.

    Miguel Alvarez-Tejado;Salvador Naranjo-Suárez;Concepción Jiménez;Ana C. Carrera

  • The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP.

    Ana C. Carrera;Kirill Alexandrov;Thomas M. Roberts

  • Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis.

    Concepción Gómez-Moutón;Rosa Ana Lacalle;Emilia Mira;Sonia Jiménez-Baranda

  • Differential requirements for DOCK2 and phosphoinositide-3-kinase γ during T and B lymphocyte homing

    César Nombela-Arrieta;Rosa Ana Lacalle;Marı́a C. Montoya;Yuya Kunisaki

  • Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead.

    Lorena Martínez-Gac;Miriam Marqués;Zaira García;Miguel R. Campanero

  • The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras.

    Concepción Jiménez;Carmen Hernández;Belén Pimentel;Ana C. Carrera

  • Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity.

    Matilde Murga;Oskar Fernández-Capetillo;Seth J. Field;Bernardino Moreno

  • Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo

    Luis R.-Borlado;Clara Redondo;Beatriz Alvarez;Concepcion Jimenez

  • Apoptosis, fas and systemic autoimmunity: the MRL-Ipr/Ipr model

    Gary G. Singer;Ana C. Carrera;Ann Marshak-Rothstein;Carlos Martínez-A

  • Nuclear phosphoinositide 3-kinase β controls double-strand break DNA repair

    Amit Kumar;Oscar Fernandez-Capetillo;Ana C. Carrera

  • Phosphoinositide 3-kinase controls early and late events in mammalian cell division

    Zaira García;Amit Kumar;Miriam Marqués;Isabel Cortés

  • Grass tablet sublingual immunotherapy downregulates the TH2 cytokine response followed by regulatory T-cell generation

    Abel Suárez-Fueyo;Tania Ramos;Agustín Galán;Lucia Jimeno

  • Modulation of the PI 3-kinase-Akt signalling pathway by IGF-I and PTEN regulates the differentiation of neural stem/precursor cells.

    Gaizka Otaegi;María J. Yusta-Boyo;Eva Vergaño-Vera;Héctor R. Méndez-Gómez

  • Blocking of HIV-1 Infection by Targeting CD4 to Nonraft Membrane Domains

    Gustavo del Real;Sonia Jiménez-Baranda;Rosa Ana Lacalle;Emilia Mira

  • Involvement of the CD4 molecule in a post-activation event on T cell proliferation.

    Ana C. Carrera;Francisco Sanchez-Madrid;Miguel Lopez-Botet;Carmelo Bernabeu

  • A cAMP-activated pathway, including PKA and PI3K, regulates neuronal differentiation.

    Santiago Sánchez;Concepción Jiménez;Ana C. Carrera;Javier Díaz-Nido

Frequent Co-Authors

Carlos Martínez-A
Carlos Martínez-A Spanish National Research Council
Thomas M. Roberts
Thomas M. Roberts Harvard University
Isabel Mérida
Isabel Mérida Spanish National Research Council
Juana M. Flores
Juana M. Flores Complutense University of Madrid
Emilio Hirsch
Emilio Hirsch University of Turin
Matthias P. Wymann
Matthias P. Wymann University of Basel
Domingo Barber
Domingo Barber CEU San Pablo University
José Miguel Rodríguez-Frade
José Miguel Rodríguez-Frade Spanish National Research Council
Mario Mellado
Mario Mellado Spanish National Research Council
José M. Valpuesta
José M. Valpuesta Spanish National Research Council

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