José Miguel Rodríguez-Frade

Best Publications

• The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway.

  Antonio J. Vila-Coro;José Miguel Rodríguez-Frade;Ana Martín De Ana;MA Carmen Moreno-Ortíz

  683
  Citations

• Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation.

  Mario Mellado;José Miguel Rodríguez-Frade;Santos Mañes;Carlos Martínez-A

  543
  Citations

• The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2.

  José Miguel Rodríguez-Frade;Antonio J. Vila-Coro;Ana Martín de Ana;Juan Pablo Albar

  329
  Citations

• Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells.

  Mar M. Robledo;Rubén Álvaro Bartolomé;Natividad Longo;José Miguel Rodríguez-Frade

  301
  Citations

• The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.

  M. Mellado;J. M. Rodríguez-Frade;A. Aragay;G. del Real

  283
  Citations

• Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis

  Marta Nieto;José M.R. Frade;David Sancho;Mario Mellado

  275
  Citations

• Identification of amino acid residues crucial for chemokine receptor dimerization.

  Patricia Hernanz-Falcón;José Miguel Rodríguez-Frade;Antonio Serrano;David Juan

  233
  Citations

• Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2

  A. M. Aragay;M. Mellado;J. M. R. Frade;A. M. Martin

  221
  Citations

• Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells.

  J. M. R. Frade;M. Mellado;G. Del Real;J. C. Gutierrez-Ramos

  220
  Citations

• CXCR3 chemokine receptor distribution in normal and inflamed tissues: expression on activated lymphocytes, endothelial cells, and dendritic cells.

  María Ángeles García-López;Francisco Sánchez-Madrid;Jose Miguel Rodríguez-Frade;Mario Mellado

  215
  Citations

• Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4

  Benhur Lee;Benjamin J. Doranz;Shalini Rana;Yanji Yi

  204
  Citations

• Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis.

  M Vicente-Manzanares;M Rey;D R Jones;D Sancho

  190
  Citations

• HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.

  A. J. Vila-Coro;M. Mellado;A. Martín de Ana;P. Lucas

  190
  Citations

• Chemokine control of HIV-1 infection

  Mario Mellado;José Miguel Rodríguez-Frade;Antonio J. Vila-Coro;Ana Martín de Ana

  186
  Citations

• Ligand stabilization of CXCR4/δ‐opioid receptor heterodimers reveals a mechanism for immune response regulation

  Oscar M. Pello;Laura Martínez-Muñoz;Verónica Parrillas;Antonio Serrano

  174
  Citations

• The amino-terminal domain of the CCR2 chemokine receptor acts as coreceptor for HIV-1 infection.

  J M Frade;M Llorente;M Mellado;J Alcamí

  168
  Citations

• The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases

  Eva M. García-Cuesta;César A. Santiago;Jesús Vallejo-Díaz;Yasmina Juarranz

  168
  Citations

• Similarities and Differences in RANTES- and (AOP)-RANTES–triggered Signals: Implications for Chemotaxis

  José M. Rodríguez-Frade;Antonio J. Vila-Coro;Ana Martín;Marta Nieto

  168
  Citations

• Chemokine receptor dimerization: two are better than one.

  José Miguel Rodrı́guez-Frade;Mario Mellado;Carlos Martı́nez-A

  164
  Citations

• Chemokines integrate JAK/STAT and G‐protein pathways during chemotaxis and calcium flux responses

  Silvia F. Soriano;Antonio Serrano;Patricia Hernanz‐Falcón;Ana Martín de Ana

  158
  Citations