Mario Mellado

Best Publications

• Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

  Frederic Sierro;Christine Biben;Laura Martínez-Muñoz;Mario Mellado

  795
  Citations

• HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

  Milena Schiraldi;Angela Raucci;Laura Martínez Muñoz;Elsa Livoti

  747
  Citations

• CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.

  Álvaro Teijeira;Saray Garasa;María Gato;Carlos Alfaro

  711
  Citations

• The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway.

  Antonio J. Vila-Coro;José Miguel Rodríguez-Frade;Ana Martín De Ana;MA Carmen Moreno-Ortíz

  683
  Citations

• CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile

  Elena Sierra-Filardi;Concha Nieto;Ángeles Domínguez-Soto;Rubén Barroso

  548
  Citations

• Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation.

  Mario Mellado;José Miguel Rodríguez-Frade;Santos Mañes;Carlos Martínez-A

  543
  Citations

• Chemokine receptor homo‐ or heterodimerization activates distinct signaling pathways

  Mario Mellado;José Miguel Rodríguez‐Frade;Antonio J. Vila‐Coro;Silvia Fernández

  538
  Citations

• The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2.

  José Miguel Rodríguez-Frade;Antonio J. Vila-Coro;Ana Martín de Ana;Juan Pablo Albar

  329
  Citations

• T cell migration in rheumatoid arthritis

  Mario Mellado;Laura Martínez-Muñoz;Graciela Cascio;Pilar Lucas

  306
  Citations

• Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells.

  Mar M. Robledo;Rubén Álvaro Bartolomé;Natividad Longo;José Miguel Rodríguez-Frade

  301
  Citations

• DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production.

  Esther Caparrós;Pilar Munoz;Elena Sierra-Filardi;Diego Serrano-Gómez

  294
  Citations

• The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.

  M. Mellado;J. M. Rodríguez-Frade;A. Aragay;G. del Real

  283
  Citations

• Polarization of Chemokine Receptors to the Leading Edge during Lymphocyte Chemotaxis

  Marta Nieto;José M.R. Frade;David Sancho;Mario Mellado

  275
  Citations

• Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds.

  César Santiago;Angela Ballesteros;Laura Martínez-Muñoz;Mario Mellado

  267
  Citations

• Identification of amino acid residues crucial for chemokine receptor dimerization.

  Patricia Hernanz-Falcón;José Miguel Rodríguez-Frade;Antonio Serrano;David Juan

  233
  Citations

• Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2

  A. M. Aragay;M. Mellado;J. M. R. Frade;A. M. Martin

  221
  Citations

• Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells.

  J. M. R. Frade;M. Mellado;G. Del Real;J. C. Gutierrez-Ramos

  220
  Citations

• CXCR3 chemokine receptor distribution in normal and inflamed tissues: expression on activated lymphocytes, endothelial cells, and dendritic cells.

  María Ángeles García-López;Francisco Sánchez-Madrid;Jose Miguel Rodríguez-Frade;Mario Mellado

  215
  Citations

• Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4

  Benhur Lee;Benjamin J. Doranz;Shalini Rana;Yanji Yi

  204
  Citations

• Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis.

  M Vicente-Manzanares;M Rey;D R Jones;D Sancho

  190
  Citations