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Immunology

D-Index
65
Citations
18617
World Ranking
2816
National Ranking
1331

Overview

Yueh-hsiu Chien is affiliated with Stanford University in the United States. Their research primarily spans the fields of Immunology and Microbiology as well as Medicine, with a focus on subfields including Immunology, Epidemiology, Gastroenterology, Oncology, and Rheumatology.

Their scholarly output includes studies on diverse topics such as:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Influenza Virus Research Studies
  • Immune Response and Inflammation
  • Celiac Disease Research and Management
  • Respiratory viral infections research

Chien has contributed to multiple research papers published in well-regarded journals. Notable recent publications include:

  • "KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19," 2022, Science
  • "A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2," 2023, Nature Materials
  • "NK-like CD8 + γδ T cells are expanded in persistent Mycobacterium tuberculosis infection," 2023, Science Immunology
  • "Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities," 2021, Proceedings of the National Academy of Sciences
  • "γδ T cell antigen receptor polyspecificity enables T cell responses to a broad range of immune challenges," 2024, Proceedings of the National Academy of Sciences

The venues where Yueh-hsiu Chien most frequently publishes include:

  • Science
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Nature Materials

Collaboration plays a significant role in their research, with frequent coauthors including:

  • Mark M. Davis
  • Jing Guo
  • Vamsee Mallajosyula
  • Elsa Solà
  • Jing Li

Best Publications

  • Ligand recognition by alpha beta T cell receptors.

    Mark M. Davis;J. Jay Boniface;Ziv Reich;Daniel Lyons

  • A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells.

    Koichi Ikuta;Tatsuo Kina;Ian MacNeil;Ian MacNeil;Nobuko Uchida

  • CDR3 length in antigen-specific immune receptors.

    E. P. Rock;P. R. Sibbald;M. M. Davis;Yueh-Hsiu Chien

  • A third type of murine T-cell receptor gene

    Yueh-hsiu Chien;Daniel M. Becker;Tullia Lindsten;Maki Okamura

  • γδ T cells: first line of defense and beyond.

    Yueh-hsiu Chien;Christina Meyer;Marc Bonneville

  • A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

    Yueh-hsiu Chien;Makio Iwashima;Kenneth B. Kaplan;John F. Elliott

  • The nature of major histocompatibility complex recognition by γδ T cells

    Hansjörg Schild;Nasim Mavaddat;Nasim Mavaddat;Christa Litzenberger;Elliot W. Ehrich

  • Somatic recombination in a murine T-cell receptor gene

    Yueh-hsiu Chien;Nicholas R. J. Gascoigne;Joshua Kavaler;Nadine E. Lee

  • Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

    Kirk D.C. Jensen;Xiaoqin Su;Sunny Shin;Luke Li

  • A TCR Binds to Antagonist Ligands with Lower Affinities and Faster Dissociation Rates Than to Agonists

    Daniel S. Lyons;Stephanie A. Lieberman;Johannes Hampl;J. Jay Boniface

  • Recognition of self antigens by skin-derived T cells with invariant γδ antigen receptors

    Wendy L. Havran;Yueh Hsiu Chien;James P. Allison

  • Genomic organization and sequence of T-cell receptor |[beta]|-chain constant- and joining-region genes

    Nicholas R. J. Gascoigne;Yueh-hsiu Chien;Daniel M. Becker;Joshua Kavaler

  • A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells.

    Jun Huang;Mario Brameshuber;Xun Zeng;Jianming Xie

  • T-cell receptor δ gene rearrangements in early thymocytes

    Yueh-Hsiu Chien;M. Iwashima;D. A. Wettstein;K. B. Kaplan

  • The adult T-cell receptor delta-chain is diverse and distinct from that of fetal thymocytes.

    John Francis Elliott;Edwin P. Rock;Phillip A. Patten;Phillip A. Patten;Mark M. Davis;Mark M. Davis

  • Recognition by gamma/delta T cells.

    Yueh-hsiu Chien;Rita Jores;Michael P. Crowley

  • KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19

    Unknown

  • Structure, expression and divergence of T-cell receptor β -chain variable regions

    Phillip Patten;Takashi Yokota;Jonathan Rothbard;Yueh-hsiu Chien

  • LIGAND RECOGNITION BY T CELL RECEPTORS

    Mark M. Davis;J. Jay Boniface;Ziv Reich;Daniel Lyons

  • Structure of a γδ T Cell Receptor in Complex with the Nonclassical MHC T22

    Erin J. Adams;Yueh-Hsiu Chien;K. Christopher Garcia

  • A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion

    Jun Huang;Mario Brameshuber;Xun Zeng;Jianming Xie

Frequent Co-Authors

Mark M. Davis
Mark M. Davis Stanford University
Nicholas R. J. Gascoigne
Nicholas R. J. Gascoigne National University of Singapore
Tullia Lindsten
Tullia Lindsten Memorial Sloan Kettering Cancer Center
Evan W. Newell
Evan W. Newell Fred Hutchinson Cancer Research Center
K. Christopher Garcia
K. Christopher Garcia Stanford University
Christopher C. Goodnow
Christopher C. Goodnow Garvan Institute of Medical Research
Erin J. Adams
Erin J. Adams University of Chicago
Gerhard Walzl
Gerhard Walzl Stellenbosch University
Koichi Ikuta
Koichi Ikuta Kyoto University
Lars M. Steinmetz
Lars M. Steinmetz Stanford University

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