Brian Burchell

Overview

Best Publications

• The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

  Peter I. Mackenzie;Ida S. Owens;Brian Burchell;K. W. Bock

  1389
  Citations

• Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.

  Peter I Mackenzie;Karl Walter Bock;Brian Burchell;Chantal Guillemette

  949
  Citations

• The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides.

  Gabriele Jedlitschky;Brian Burchell;Dietrich Keppler

  560
  Citations

• ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2

  Gabriele Jedlitschky;Inka Leier;Ulrike Buchholz;Johanna Hummel-Eisenbeiss

  407
  Citations

• The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

  Brian Burchell;Daniel W. Nebert;David R. Nelson;Karl W. Bock

  368
  Citations

• Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation.

  Sahidan Senafi;D. J. Clarke;B. Burchell

  346
  Citations

• UDP-glucuronosyltransferases: a family of detoxifying enzymes.

  Thomas R. Tephly;Brian Burchell

  343
  Citations

• The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes.

  M. W. H. Coughtrie;B. Burchell;J. E. A. Leakey;R. Hume

  319
  Citations

• In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance.

  M. G. Soars;B. Burchell;R. J. Riley

  309
  Citations

• Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation.

  Brian Burchell;Catherine H Brierley;David Rance

  308
  Citations

• UDP-GLUCURONOSYLTRANSFERASE ACTIVITIES - GUIDELINES FOR CONSISTENT INTERIM TERMINOLOGY AND ASSAY CONDITIONS

  Karl Walter Bock;Brian Burchell;Geoffrey J. Dutton;Osmo Hänninen

  283
  Citations

• A new microtechnique for the analysis of the human hepatic microsomal glucose-6-phosphatase system.

  Ann Burchell;Robert Hume;Brian Burchell

  246
  Citations

• Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells.

  David Harding;Sylvie Fournel-Gigleux;Michael R. Jackson;Brian Burchell

  242
  Citations

• Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases.

  Karl Walter Bock;Adelheid Forster;Harald Gschaidmeier;Marianne Brück

  202
  Citations

• Genetic defects of the UDP-glucuronosyltransferase-1 (UGT1) gene that cause familial non-haemolytic unconjugated hyperbilirubinaemias

  Douglas J. Clarke;Nabil Moghrabi;Gemma Monaghan;Andrew Cassidy

  192
  Citations

• Gilbert's syndrome is a contributory factor in prolonged unconjugated hyperbilirubinemia of the newborn.

  Gemma Monaghan;Ailsa McLellan;Anne McGeehan;Salvatore Li Volti

  183
  Citations

• Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank.

  Michael B. Fisher;Mark Vandenbranden;Karen Findlay;Brian Burchell

  183
  Citations

• Drug glucuronidation by human renal UDP-glucuronosyltransferases.

  Karen A McGurk;Catherine H Brierley;Brian Burchell

  178
  Citations

• GLUCURONIDATION OF DIHYDROARTEMISININ IN VIVO AND BY HUMAN LIVER MICROSOMES AND EXPRESSED UDP-GLUCURONOSYLTRANSFERASES

  Kenneth F. Ilett;Brian T. Ethell;James L. Maggs;Timothy M. E. Davis

  175
  Citations

• The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases

  Brian T Ethell;Gail D Anderson;Brian Burchell

  173
  Citations