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Karl Walter Bock

Karl Walter Bock

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
15247
World Ranking
9138
National Ranking
661

Overview

Karl Walter Bock is affiliated with the University of Tübingen in Germany. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with published work in subfields including Physiology, Immunology, Biological Psychiatry, Molecular Biology, and Nutrition and Dietetics.

The main topics of their work cover areas such as Calcium signaling and nucleotide metabolism, Tryptophan and brain disorders, Immune Cell Function and Interaction, Vitamin C and Antioxidants Research, Folate and B Vitamins Research, Sirtuins and Resveratrol in Medicine, and Adipose Tissue and Metabolism.

Their recent scholarly articles have been published predominantly in the journal Biochemical Pharmacology, with additional work appearing in Archives of Toxicology and Frontiers in Toxicology. The recent papers include:

  • Aryl hydrocarbon receptor (AHR) functions: Balancing opposing processes including inflammatory reactions, 2020, Biochemical Pharmacology
  • Aryl hydrocarbon receptor (AHR)-mediated inflammation and resolution: Non-genomic and genomic signaling, 2020, Biochemical Pharmacology
  • Aryl hydrocarbon receptor (AHR), integrating energy metabolism and microbial or obesity-mediated inflammation, 2020, Biochemical Pharmacology
  • Modulation of aryl hydrocarbon receptor (AHR) and the NAD+-consuming enzyme CD38: Searches of therapeutic options for nonalcoholic fatty liver disease (NAFLD), 2020, Biochemical Pharmacology
  • Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation, 2021, Archives of Toxicology

The body of work demonstrates a consistent interest in the aryl hydrocarbon receptor (AHR) and its roles in inflammation, metabolic processes, and immune function. These studies explore various dimensions of AHR signaling pathways, including non-genomic and genomic mechanisms, and their implications for diseases such as nonalcoholic fatty liver disease.

Their publications span multiple years but are notably concentrated in 2020, indicating a period of intensive research output in this area. Besides the scientific articles, their work does not list any book publications.

Karl Walter Bock has not been noted to have frequent co-authors. The choice of journals and topics reflects a specialized research agenda heavily centered on molecular mechanisms and their physiological and pathological relevance.

Best Publications

  • The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

    Peter I. Mackenzie;Ida S. Owens;Brian Burchell;K. W. Bock

  • Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.

    Peter I Mackenzie;Karl Walter Bock;Brian Burchell;Chantal Guillemette

  • Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions.

    Karl Walter Bock;Christoph Köhle

  • Coordinate regulation of Phase I and II xenobiotic metabolisms by the Ah receptor and Nrf2.

    Christoph Köhle;Karl Walter Bock

  • The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

    Brian Burchell;Daniel W. Nebert;David R. Nelson;Karl W. Bock

  • Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.

    Karl W. Bock;Wolfgang Fröhling;Herbert Remmer;Bernhard Rexer

  • Purification of rat-liver microsomal UDP-glucuronyltransferase. Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital.

    Karl Walter Bock;Dorothee Josting;Werner Lilienblum;Hugo Pfeil

  • The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes.

    Karl Bock;Dieter Schrenk;Adelheid Forster;Ernst-Ulrich Griese

  • UDP-GLUCURONOSYLTRANSFERASE ACTIVITIES - GUIDELINES FOR CONSISTENT INTERIM TERMINOLOGY AND ASSAY CONDITIONS

    Karl Walter Bock;Brian Burchell;Geoffrey J. Dutton;Osmo Hänninen

  • UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene.

    Karl Walter Bock;Ian N. H. White

  • Differential induction of rat liver microsomal UDP-glucuronosyltransferase activities by various inducing agents

    Werner Lilienblum;Autar K. Walli;Karl Walter BocK

  • Inhibition of apoptosis during 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver

    Stefan Stinchcombe;Albrecht Buchmann;Karl Walter Bock;Michael Schwarz

  • Profiles of strontium and barium in Mercenaria mercenaria and Spisula solidissima shells

    H.A. Stecher;D.E. Krantz;C.J. Lord;G.W. Luther

  • The UDP-glycosyltransferase (UGT) superfamily expressed in humans, insects and plants: Animal-plant arms-race and co-evolution.

    Karl Walter Bock

  • Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases.

    Karl Walter Bock;Adelheid Forster;Harald Gschaidmeier;Marianne Brück

  • Vertebrate UDP-glucuronosyltransferases: functional and evolutionary aspects.

    Karl Walter Bock

  • Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor.

    Christoph Köhle;Karl Walter Bock

  • Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism

    M. Diry;C. Tomkiewicz;C. Koehle;Xavier Coumoul

  • Activation of coupled Ah receptor and Nrf2 gene batteries by dietary phytochemicals in relation to chemoprevention

    Christoph Köhle;Karl Walter Bock

  • Dioxinlike components in incinerator fly ash: a comparison between chemical analysis data and results from a cell culture bioassay.

    Markus Till;Peter Behnisch;Hanspaul Hagenmaier;Karl Walter Bock

Frequent Co-Authors

Brian Burchell
Brian Burchell University of Dundee
Dieter Schrenk
Dieter Schrenk Technical University of Kaiserslautern
Thomas R. Tephly
Thomas R. Tephly University of Iowa
Franz Oesch
Franz Oesch Johannes Gutenberg University of Mainz
Peter I. Mackenzie
Peter I. Mackenzie Flinders University
Daniel W. Nebert
Daniel W. Nebert University of Cincinnati
Magnus Ingelman-Sundberg
Magnus Ingelman-Sundberg Karolinska Institute
Michel Eichelbaum
Michel Eichelbaum University of Tübingen
Doron Lancet
Doron Lancet Weizmann Institute of Science
Michael Schwarz
Michael Schwarz Helmholtz Center for Information Security

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