Pierre P. Roger

Overview

Best Publications

• Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors

  Jacques Emile Dumont;Françoise Lamy;Pierre P. Roger;Carine Maenhaut

  710
  Citations

• The cyclic AMP-mediated stimulation of cell proliferation

  Jacques Emile Dumont;Jean Claude Jauniaux;Pierre P. Roger

  632
  Citations

• Regulation of Thyroid Cell Proliferation by TSH and Other Factors: A Critical Evaluation of in Vitro Models

  Takao Kimura;Alexandra Van Keymeulen;Jacqueline Golstein;Alfredo Fusco

  613
  Citations

• Mitogenic effects of thyrotropin and adenosine 3',5'-monophosphate in differentiated normal human thyroid cells in vitro.

  Pierre P. Roger;Martine Taton;Jacqueline Van Sande;Jacques Emile Dumont

  253
  Citations

• Factors controlling proliferation and differentiation of canine thyroid cells cultured in reduced serum conditions: effects of thyrotropin, cyclic AMP and growth factors.

  Pierre P. Roger;Pierre P. Roger;Jacques Emile Dumont;Jacques Emile Dumont

  250
  Citations

• Stimulation by thyrotropin and cyclic AMP of the proliferation of quiescent canine thyroid cells cultured in a defined medium containing insulin

  Pierre P. Roger;Patricia Servais;Jacques E. Dumont

  164
  Citations

• Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells

  Pierre P. Roger;Brigitte Van Heuverswyn;Christine Lambert;Sophie Reuse

  149
  Citations

• Epidermal growth factor controls the proliferation and the expression of differentiation in canine thyroid cells in primary culture

  Pierre P. Roger;Pierre P. Roger;Jacques Emile Dumont;Jacques Emile Dumont

  144
  Citations

• Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway.

  Françoise Lamy;Françoise Wilkin;Mireille Baptist;James Posada

  138
  Citations

• Growth factors controlling the thyroid gland

  Jacques Emile Dumont;Carine Maenhaut;Isabelle Pirson;Mireille Baptist

  137
  Citations

• Stimulation by thyrotropin, cholera toxin and dibutyryl cyclic AMP of the multiplication of differentiated thyroid cells in vitro

  Pierre P. Roger;Anouk Hotimsky;Colette Moreau;Jacques Emile Dumont

  134
  Citations

• Stimulation of Cell Proliferation and Inhibition of Differentiation Expression by Tumor-promoting Phorbol Esters in Dog Thyroid Cells in Primary Culture

  Pierre P. Roger;Sylvia Reuse;Patricia Servais;Brigitte Van Heuverswyn

  128
  Citations

• p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway.

  M. Farhang Ghahremani;S. Goossens;D. Nittner;X. Bisteau

  126
  Citations

• Multiple Facets of the Modulation of Growth by cAMP

  Pierre P. Roger;Sophie Reuse;Carine Maenhaut;Jacques Emile Dumont

  126
  Citations

• Induction of DNA synthesis in dog thyrocytes in primary culture: synergistic effects of thyrotropin and cyclic AMP with epidermal growth factor and insulin.

  Pierre P. Roger;Patricia Servais;Jacques Emile Dumont;Jacques Emile Dumont

  123
  Citations

• Rb inactivation in cell cycle and cancer: the puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase.

  Sabine Paternot;Laurence Bockstaele;Xavier Bisteau;Hugues Kooken

  113
  Citations

• Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells.

  Sarah Dremier;Viviane Pohl;C. Poteet-Smith;Pierre P. Roger

  108
  Citations

• Cancer stem cells: a reality, a myth, a fuzzy concept or a misnomer? An analysis

  C. Maenhaut;J.E. Dumont;P.P. Roger;W.C.G. van Staveren

  105
  Citations

• The dog thyroid primary culture system: a model of the regulation of function, growth and differentiation expression by cAMP and other well-defined signaling cascades

  Pierre P. Roger;Daniel Christophe;Jacques Emile Dumont;Isabelle Pirson

  104
  Citations

• Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).

  Fabienne Depoortere;Isabelle Pirson;Jiri Bartek;Jacques Emile Dumont

  103
  Citations