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Biology and Biochemistry

D-Index
55
Citations
15396
World Ranking
14824
National Ranking
261

Overview

Frédérick Libert is affiliated with the Université Libre de Bruxelles in Belgium. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. The work also delves into several subfields, including Immunology, Oncology, Molecular Biology, Pulmonary and Respiratory Medicine, and Genetics.

The scientist's research explores multiple topics such as:

  • Cancer Cells and Metastasis
  • Digestive system and related health
  • Advanced Breast Cancer Therapies
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Congenital Diaphragmatic Hernia Studies
  • Gut microbiota and health

Their recent scholarly work includes publications in a variety of peer-reviewed journals. Notable papers are:

  • "Identification of distinct functional thymic programming of fetal and pediatric human γδ thymocytes via single-cell analysis," 2022, Nature Communications
  • "Functional reprogramming of monocytes in patients with acute and convalescent severe COVID-19," 2022, JCI Insight
  • "LGR 5 controls extracellular matrix production by stem cells in the developing intestine," 2020, EMBO Reports
  • "Transcriptomic Signature of Human Embryonic Thyroid Reveals Transition From Differentiation to Functional Maturation," 2021, Frontiers in Cell and Developmental Biology
  • "The mononuclear phagocyte system contributes to fibrosis in post-transplant obliterans bronchiolitis," 2020, European Respiratory Journal

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), EMBO Reports, Frontiers in Cell and Developmental Biology, Nature Communications, and JCI Insight.

Collaborative research efforts include partnerships with colleagues such as Anne Lefort, Morgane Leprovots, Marie-Isabelle Garcia, Gilles Dinsart, and Gilbert Vassart. Anne Lefort is noted as a frequent co-author contributing to 22 shared publications, while Morgane Leprovots and Marie-Isabelle Garcia each have collaborated on 10 publications.

Best Publications

  • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

    Michel Samson;Frédérick Libert;Benjamin J. Doranz;Joseph Rucker

  • Selective amplification and cloning of four new members of the G protein-coupled receptor family.

    F Libert;M Parmentier;A Lefort;C Dinsart

  • Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

    Xavier De Deken;Dantong Wang;Marie-Christine Many;Sabine Costagliola

  • Molecular cloning of the thyrotropin receptor

    M Parmentier;F Libert;C Maenhaut;A Lefort

  • Expression of members of the putative olfactory receptor gene family in mammalian germ cells

    Marc Parmentier;Frédérick Libert;Stéphane Schurmans;Serge N. Schiffmann

  • Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies.

    Frédérick Libert;Anne Lefort;Catherine Gerard;Marc Parmentier

  • Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor Specificity

    Joseph Rucker;Michel Samson;Benjamin J Doranz;Frédérick Libert

  • The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe

    Frédérick Libert;Pascale Cochaux;Gunhild Beckman;Michel Samson

  • RDC8 codes for an adenosine A2 receptor with physiological constitutive activity.

    Carine Maenhaut;Jacqueline Van Sande;Frédérick Libert;Marc Abramowicz

  • Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.

    Shalini Rana;Gideon Besson;David G. Cook;Joseph Rucker

  • The second extracellular loop of CCR5 is the major determinant of ligand specificity.

    Michel Samson;Gregory LaRosa;Frédérick Libert;Pascale Paindavoine

  • The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.

    Frédérick Libert;Serge N. Schiffmann;Anne Lefort;Marc Parmentier

  • Identification of Lgr5-Independent Spheroid-Generating Progenitors of the Mouse Fetal Intestinal Epithelium

    Roxana C. Mustata;Gabriela Vasile;Valeria Fernandez-Vallone;Sandra Strollo

  • Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.

    Cédric Blanpain;Benjamin J. Doranz;Jalal Vakili;Joseph Rucker

  • Distribution of adenosine A2 receptor mRNA in the human brain.

    Serge N. Schiffmann;Frédérick Libert;Gilbert Vassart;Jean-Jacques Vanderhaeghen

  • Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.

    Debora Fumagalli;David Gacquer;Françoise Rothé;Anne Lefort

  • Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.

    Dominique Eggerickx;Jean François Denef;Olivier Labbe;Y. Hayashi

  • LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

    Marie Isabelle Garcia;Mariangela Ghiani;Anne Lefort;Frédérick Libert

  • Modulation of murine dendritic cell function by adenine nucleotides and adenosine: Involvement of the A2B receptor

    Abduelhakem Ben Addi;Anne Lefort;Xiaoyang Hua;Frédérick Libert

  • Cloning and functional characterization of a human A1 adenosine receptor.

    Frédérick Libert;Jacqueline Van Sande;Anne Lefort;Armin Czernilofsky

Frequent Co-Authors

Gilbert Vassart
Gilbert Vassart Université Libre de Bruxelles
Jacques Emile Dumont
Jacques Emile Dumont Université Libre de Bruxelles
Marc Parmentier
Marc Parmentier Université Libre de Bruxelles
Carine Maenhaut
Carine Maenhaut Université Libre de Bruxelles
Serge N. Schiffmann
Serge N. Schiffmann Université Libre de Bruxelles
Sabine Costagliola
Sabine Costagliola Université Libre de Bruxelles
Jean-Jacques Vanderhaeghen
Jean-Jacques Vanderhaeghen Université Libre de Bruxelles
Robert W. Doms
Robert W. Doms Children's Hospital of Philadelphia
Ronald G. Collman
Ronald G. Collman University of Pennsylvania
Benjamin J. Doranz
Benjamin J. Doranz University of Pennsylvania

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