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Neuroscience

D-Index
74
Citations
19489
World Ranking
2117
National Ranking
20

Overview

Serge N. Schiffmann is affiliated with the Université Libre de Bruxelles in Belgium. Their research primarily spans neuroscience and biochemistry, genetics, and molecular biology, with a focused interest in cellular and molecular neuroscience as well as molecular biology. The scientist's work also touches on neurology, social psychology, and biophysics.

The main topics covered in their research include:

  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Genetic Neurodegenerative Diseases
  • Photoreceptor and Optogenetics Research
  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering

Recent publications by Serge N. Schiffmann illustrate their focus on neural mechanisms, stem cell models, and neurodegenerative disorders. These papers include:

  • "Primary proprioceptive neurons from human induced pluripotent stem cells: a cell model for afferent ataxias," 2020, Scientific Reports
  • "The Effect of Serotonin Receptor 5-HT1B on Lateral Inhibition between Spiny Projection Neurons in the Mouse Striatum," 2021, Journal of Neuroscience
  • "Proprioceptors-enriched neuronal cultures from induced pluripotent stem cells from Friedreich ataxia patients show altered transcriptomic and proteomic profiles, abnormal neurite extension, and impaired electrophysiological properties," 2022, Brain Communications
  • "Mammalian Target of Rapamycin-RhoA Signaling Impairments in Direct Striatal Projection Neurons Induce Altered Behaviors and Striatal Physiology in Mice," 2020, Biological Psychiatry
  • "Dopamine-mediated striatal activity and function is enhanced in GlyRα2 knockout animals," 2023, iScience

The scientist regularly publishes in the following academic venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroscience
  • European Journal of Neuroscience
  • Scientific Reports
  • Brain Communications

Frequent collaborators in their research include:

  • Marine Chazalon
  • Alban de Kerchove d'Exaerde
  • Chiara Dionisi
  • Myriam Rai
  • Massimo Pandolfo

Best Publications

  • The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.

    Masato Kotani;Michel Detheux;Ann Vandenbogaerde;David Communi

  • Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor.

    Catherine Ledent;Jean-Marie Vaugeois;Serge N. Schiffmann;Thierry Pedrazzini

  • An intrinsic mechanism of corticogenesis from embryonic stem cells

    Nicolas Gaspard;Tristan Bouschet;Raphael Hourez;Jordane Dimidschstein

  • Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.

    Ira Espuny-Camacho;Kimmo A. Michelsen;David Gall;Daniele Linaro

  • Striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: an in situ hybridization histochemistry study.

    Serge N. Schiffmann;Olivier Jacobs;Jean‐Jacques Vanderhaeghen

  • Expression of members of the putative olfactory receptor gene family in mammalian germ cells

    Marc Parmentier;Frédérick Libert;Stéphane Schurmans;Serge N. Schiffmann

  • Adenosine A2A receptors and basal ganglia physiology.

    Serge N. Schiffmann;Gilberto Fisone;R Moresco;Rodrigo Antunes Cunha

  • 'New' functions for 'old' proteins: the role of the calcium-binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with knockout mice.

    Beat Schwaller;Michael Meyer;Michael Meyer;Serge Schiffmann

  • Nitric Oxide Synthase Activity in Infantile Hypertrophic Pyloric Stenosis

    J M Vanderwinden;P Mailleux;S N Schiffmann;J J Vanderhaeghen

  • RDC8 codes for an adenosine A2 receptor with physiological constitutive activity.

    Carine Maenhaut;Jacqueline Van Sande;Frédérick Libert;Marc Abramowicz

  • D2R striatopallidal neurons inhibit both locomotor and drug reward processes

    Pierre F Durieux;Bertrand Bearzatto;Stefania Guiducci;Thorsten Buch

  • An Update on Adenosine A2A-Dopamine D2 Receptor Interactions: Implications for the Function of G Protein-Coupled Receptors

    Sergi Ferré;César Quiroz;A S Woods;Rodrigo Antunes Cunha

  • Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output

    Marcelo Chávez;Sabrina Ena;Jacqueline Van Sande;Alban de Kerchove d’Exaerde

  • Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions

    Pierre F Durieux;Serge N Schiffmann;Alban de Kerchove d'Exaerde

  • Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons.

    Serge N. Schiffmann;Jean-Jacques Vanderhaeghen

  • Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities.

    M. Wöhr;D. Orduz;Patrick Gregory;H Moreno

  • Reelin mRNA Expression During Mouse Brain Development

    Serge N. Schiffmann;B Bernier;André Goffinet

  • The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.

    Frédérick Libert;Serge N. Schiffmann;Anne Lefort;Marc Parmentier

  • Distribution of adenosine A2 receptor mRNA in the human brain.

    Serge N. Schiffmann;Frédérick Libert;Gilbert Vassart;Jean-Jacques Vanderhaeghen

  • Dopamine D2 and adenosine A2A receptors regulate NMDA-mediated excitation in accumbens neurons through A2A-D2 receptor heteromerization.

    Karima Azdad;David Gall;David Gall;Amina S Woods;Catherine Ledent

Frequent Co-Authors

Jean-Jacques Vanderhaeghen
Jean-Jacques Vanderhaeghen Université Libre de Bruxelles
Guy Cheron
Guy Cheron Université Libre de Bruxelles
David Blum
David Blum University of Lille
Massimo Pandolfo
Massimo Pandolfo McGill University
Michael Lazarus
Michael Lazarus University of Tsukuba
Zhi-Li Huang
Zhi-Li Huang Fudan University
Egidio D'Angelo
Egidio D'Angelo University of Pavia
Michele Zoli
Michele Zoli University of Modena and Reggio Emilia
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse
Bernard Dan
Bernard Dan Université Libre de Bruxelles

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