Benjamin J. Doranz mainly focuses on Virology, Chemokine receptor, Coreceptor activity, Chemokine receptor CCR5 and Receptor. His study of Virus is a part of Virology. While the research belongs to areas of Virus, Benjamin J. Doranz spends his time largely on the problem of T cell, intersecting his research to questions surrounding CXCR4.
His biological study spans a wide range of topics, including Chemokine Receptor Gene, Lipid bilayer fusion and Null allele. His Chemokine Receptor Gene research is multidisciplinary, incorporating elements of Allele and Allele frequency. His Receptor research incorporates themes from Simian immunodeficiency virus and Cell biology.
Virology, Epitope, Antibody, Monoclonal antibody and Virus are his primary areas of study. In his work, Simian immunodeficiency virus is strongly intertwined with Chemokine receptor, which is a subfield of Virology. Benjamin J. Doranz combines subjects such as Molecular biology, Glycoprotein and Ebolavirus with his study of Epitope.
His Antibody study integrates concerns from other disciplines, such as G protein-coupled receptor, Flavivirus and Hepatitis C virus. He interconnects Mutagenesis, Alphavirus, Computational biology and Zika virus in the investigation of issues within Monoclonal antibody. His Virus research is multidisciplinary, relying on both T cell and CXCR4.
The scientist’s investigation covers issues in Antibody, Virology, Epitope, Monoclonal antibody and Neutralization. His study in Antibody is interdisciplinary in nature, drawing from both Biochemistry, Computational biology, Immune system and In vivo. His work in Virology covers topics such as B cell which are related to areas like Transcriptome.
The study incorporates disciplines such as In vitro, Neutralizing antibody, Ebola virus, Somatic hypermutation and Glycoprotein in addition to Epitope. His Monoclonal antibody research incorporates themes from Cell, G protein-coupled receptor, Humoral immunity, Antigen and Mutagenesis. His Virus research integrates issues from Protein domain and Recombinant DNA.
His scientific interests lie mostly in Virology, Antibody, Epitope, Monoclonal antibody and Neutralization. His Virology study deals with Antigen intersecting with Viral envelope. His Antibody research incorporates elements of Vero cell, In vitro, Plasma protein binding, Mutation and Protein folding.
In his study, Epitope mapping, Antibody Repertoire and Molecular mimicry is strongly linked to Ebola virus, which falls under the umbrella field of Epitope. His Receptor research extends to Monoclonal antibody, which is thematically connected. His work focuses on many connections between Virus and other disciplines, such as Recombinant DNA, that overlap with his field of interest in Mutagenesis, Enzyme and Protein domain.
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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.
Michel Samson;Frédérick Libert;Benjamin J. Doranz;Joseph Rucker.
A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors
Benjamin J Doranz;Joseph Rucker;Yanjie Yi;Robert J Smyth.
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
John F. Engelhardt;Xuehai Ye;Benjamin Doranz;James M. Wilson.
Proceedings of the National Academy of Sciences of the United States of America (1994)
A Seven-Transmembrane Domain Receptor Involved in Fusion and Entry of T-cell-tropic Human Immunodeficiency Virus Type 1 Strains
J F Berson;D Long;B J Doranz;J Rucker.
Journal of Virology (1996)
A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor
Benjamin J. Doranz;Kathie Grovit-Ferbas;Matthew P. Sharron;Si-Hua Mao.
Journal of Experimental Medicine (1997)
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function.
Benhur Lee;Benhur Lee;Matthew Sharron;Cedric Blanpain;Benjamin J. Doranz.
Journal of Biological Chemistry (1999)
Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells
Daniela Weiskopf;Michael A. Angelo;Elzinandes L. de Azeredo;John Sidney.
Proceedings of the National Academy of Sciences of the United States of America (2013)
Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses.
Joseph Rucker;Aimee L. Edinger;Matthew Sharron;Michel Samson.
Journal of Virology (1997)
Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor Specificity
Joseph Rucker;Michel Samson;Benjamin J Doranz;Frédérick Libert.
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.
Cédric Blanpain;Cédric Blanpain;Isabelle Migeotte;Isabelle Migeotte;Benhur Lee;Benhur Lee;Jalal Vakili;Jalal Vakili.
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