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Microbiology

D-Index
69
Citations
21953
World Ranking
2005
National Ranking
848

Overview

Benjamin J. Doranz is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on medicine with significant contributions to infectious diseases, radiology, nuclear medicine and imaging, public health, environmental and occupational health, molecular biology, and immunology.

The main topics in their work include monoclonal and polyclonal antibodies research, SARS-CoV-2 and COVID-19 research, mosquito-borne diseases and control, viral infections and vectors, viral infections and outbreaks research, viral gastroenteritis research and epidemiology, and viral infections and immunology research.

Some of the recent papers authored or co-authored by Benjamin J. Doranz are:

  • Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein (2021, Cell)
  • Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape (2021, Nature Communications)
  • Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals (2021, Cell Reports)
  • Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization (2020, Immunity)
  • Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor (2020, Nature Medicine)

Frequent collaborators include:

  • Edgar Davidson
  • James E. Crowe
  • Robert H. Carnahan
  • Joseph Rucker
  • Pavlo Gilchuk

They have published extensively in several venues, with the most frequent being:

  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Communications

Best Publications

  • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

    Michel Samson;Frédérick Libert;Benjamin J. Doranz;Joseph Rucker

  • A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors.

    Benjamin J Doranz;Joseph Rucker;Yanjie Yi;Robert J Smyth

  • Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver

    John F. Engelhardt;Xuehai Ye;Benjamin Doranz;James M. Wilson

  • Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

    Daniela Weiskopf;Michael A. Angelo;Elzinandes L. de Azeredo;John Sidney

  • A Seven-Transmembrane Domain Receptor Involved in Fusion and Entry of T-cell-tropic Human Immunodeficiency Virus Type 1 Strains

    J F Berson;D Long;B J Doranz;J Rucker

  • Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function.

    Benhur Lee;Benhur Lee;Matthew Sharron;Cedric Blanpain;Benjamin J. Doranz

  • A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor

    Benjamin J. Doranz;Kathie Grovit-Ferbas;Matthew P. Sharron;Si-Hua Mao

  • Mxra8 is a receptor for multiple arthritogenic alphaviruses

    Rong Zhang;Arthur S. Kim;Julie M. Fox;Sharmila Nair

  • Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

    Gopal Sapparapu;Estefania Fernandez;Nurgun Kose;Bin Cao

  • Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses.

    Joseph Rucker;Aimee L. Edinger;Matthew Sharron;Michel Samson

  • Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor Specificity

    Joseph Rucker;Michel Samson;Benjamin J Doranz;Frédérick Libert

  • Tackling soil diversity with the assembly of large, complex metagenomes

    Adina Chuang Howe;Janet K. Jansson;Janet K. Jansson;Stephanie A. Malfatti;Susannah G. Tringe

  • Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein.

    Naveenchandra Suryadevara;Swathi Shrihari;Pavlo Gilchuk;Laura A. VanBlargan

  • CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.

    Cédric Blanpain;Isabelle Migeotte;Isabelle Migeotte;Benhur Lee;Benhur Lee;Jalal Vakili;Jalal Vakili

  • CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

    Aimee L. Edinger;Joseph L. Mankowski;Benjamin J. Doranz;Barry J. Margulies

  • Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.

    B J Doranz;Z H Lu;J Rucker;T Y Zhang

  • Identification of CXCR4 Domains That Support Coreceptor and Chemokine Receptor Functions

    Benjamin J. Doranz;Michael J. Orsini;Julie D. Turner;Trevor L. Hoffman

  • Adenovirus-Mediated Transfer of the CFTR Gene to Lung of Nonhuman Primates: Biological Efficacy Study

    John F. Engelhardt;Richard H. Simon;Yiping Yang;Monica Zepeda

  • Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains

    Aimee L. Edinger;Angela Amedee;Karen Miller;Benjamin J. Doranz

  • Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.

    Cédric Blanpain;Benjamin J. Doranz;Jalal Vakili;Joseph Rucker

Frequent Co-Authors

James E. Crowe
James E. Crowe Vanderbilt University Medical Center
Robert W. Doms
Robert W. Doms Children's Hospital of Philadelphia
Michael S. Diamond
Michael S. Diamond Washington University in St. Louis
Marc Parmentier
Marc Parmentier Université Libre de Bruxelles
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Aravinda M. de Silva
Aravinda M. de Silva University of North Carolina at Chapel Hill
Olivier Elemento
Olivier Elemento Cornell University
Xiangguo Qiu
Xiangguo Qiu Public Health Agency of Canada
Benhur Lee
Benhur Lee Icahn School of Medicine at Mount Sinai
Hannah L. Turner
Hannah L. Turner Scripps Research Institute

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