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Microbiology

D-Index
49
Citations
9129
World Ranking
4563
National Ranking
133

Overview

Xiangguo Qiu is affiliated with the Public Health Agency of Canada and focuses primarily on medical research within the domain of infectious diseases. Their work spans multiple subfields including infectious diseases, epidemiology, immunology, public health, environmental and occupational health, as well as modeling and simulation. The main thematic areas of Qiu's research include viral infections and outbreaks, viral infections and vectors, and studies related to SARS-CoV-2 and COVID-19.

The scientist's publication record shows contributions to a variety of journals, frequently appearing in The Journal of Infectious Diseases. Other venues that have published Qiu's work include bioRxiv (Cold Spring Harbor Laboratory), Microorganisms, Nature Biotechnology, and mAbs.

Key recent papers authored or coauthored by Xiangguo Qiu include:

  • Biological activity-based modeling identifies antiviral leads against SARS-CoV-2, 2021, Nature Biotechnology
  • Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors, 2020, mAbs
  • Novel low-avidity glypican-3 specific CARTs resist exhaustion and mediate durable antitumor effects against HCC, 2021, Hepatology
  • The Ferret as a Model for Filovirus Pathogenesis and Countermeasure Evaluation, 2020, ILAR Journal
  • Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop, 2021, mBio

Their frequent coauthors include Shihua He, Logan Banadyga, Wenjun Zhu, Wenguang Cao, and Kevin Tierney. This suggests collaborative research efforts across different specializations within virology and infectious disease study.

Major research topics addressed through Qiu's publications are:

  • Viral Infections and Outbreaks Research
  • Viral Infections and Vectors
  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Mosquito-borne diseases and control
  • Hepatitis B Virus Studies
  • COVID-19 epidemiological studies

This body of work is situated in the broader field of medicine, with a clear emphasis on disease mechanisms, immune response, and viral pathogenesis. The integration of modeling and simulation alongside empirical studies indicates a multidisciplinary approach to understanding and controlling infectious diseases.

Best Publications

  • Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

    Xiangguo Qiu;Gary Wong;Jonathan Audet;Alexander Bello

  • Nanozyme-strip for rapid local diagnosis of Ebola.

    Demin Duan;Kelong Fan;Dexi Zhang;Shuguang Tan

  • Successful Treatment of Ebola Virus–Infected Cynomolgus Macaques with Monoclonal Antibodies

    Xiangguo Qiu;Jonathan Audet;Gary Wong;Stephane Pillet

  • A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.

    Bronwyn M. Gunn;Wen Han Yu;Marcus M. Karim;Jennifer M. Brannan

  • Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus

    Qihui Wang;Huabing Yang;Huabing Yang;Xiaoqing Liu;Lianpan Dai

  • Structures of protective antibodies reveal sites of vulnerability on Ebola virus

    Charles D. Murin;Marnie L. Fusco;Zachary A. Bornholdt;Xiangguo Qiu

  • Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection

    Erica Ollmann Saphire;Sharon L. Schendel;Marnie L. Fusco;Karthik Gangavarapu

  • Immune Parameters Correlate with Protection Against Ebola Virus Infection in Rodents and Nonhuman Primates

    Gary Wong;Jason S. Richardson;Stéphane Pillet;Ami Patel;Ami Patel

  • Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.

    Shu Yang;Miao Xu;Emily M. Lee;Kirill Gorshkov

  • Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses

    Anna Z. Wec;Andrew S. Herbert;Charles D. Murin;Elisabeth K. Nyakatura

  • Mucosal Immunization of Cynomolgus Macaques with the VSVΔG/ZEBOVGP Vaccine Stimulates Strong Ebola GP-Specific Immune Responses

    Xiangguo Qiu;Lisa Fernando;Judie B. Alimonti;Judie B. Alimonti;P. Leno Melito

  • Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies

    Xiangguo Qiu;Judie B. Alimonti;Judie B. Alimonti;P. Leno Melito;Lisa Fernando

  • Dual-Signal Readout Nanospheres for Rapid Point-of-Care Detection of Ebola Virus Glycoprotein

    Jiao Hu;Yong-Zhong Jiang;Ling-Ling Wu;Zhen Wu

  • Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina.

    Jimmy de Melo;Xiangguo Qiu;Guoyan Du;Leah Cristante

  • mAbs and Ad-Vectored IFN-α Therapy Rescue Ebola-Infected Nonhuman Primates When Administered After the Detection of Viremia and Symptoms

    Xiangguo Qiu;Gary Wong;Gary Wong;Lisa Fernando;Jonathan Audet;Jonathan Audet

  • Characterization of host immune responses in Ebola virus infections

    Gary Wong;Gary P Kobinger;Xiangguo Qiu

  • Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

    Xiangguo Qiu;Jonathan Audet;Gary Wong;Lisa Fernando

  • Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability

    Xuelian Zhao;Katie A. Howell;Shihua He;Shihua He;Jennifer M. Brannan

  • Ebola viral load at diagnosis associates with patient outcome and outbreak evolution

    Marc Antoine De La Vega;Grazia Caleo;Jonathan Audet;Xiangguo Qiu

  • Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus.

    Jonathan Audet;Gary Wong;Han Wang;Guangwen Lu

  • The multiple roles of sGP in Ebola pathogenesis

    Marc-Antoine de La Vega;Gary Wong;Gary P. Kobinger;Xiangguo Qiu

Frequent Co-Authors

Gary Wong
Gary Wong Public Health Agency of Canada
Gary Kobinger
Gary Kobinger The University of Texas Medical Branch at Galveston
George F. Gao
George F. Gao Chinese Center For Disease Control and Prevention
Heinz Feldmann
Heinz Feldmann National Institutes of Health
Yuhai Bi
Yuhai Bi Chinese Academy of Sciences
John M. Dye
John M. Dye United States Army Medical Research Institute of Infectious Diseases
Steven M. Jones
Steven M. Jones University of Saskatchewan
Kartik Chandran
Kartik Chandran Albert Einstein College of Medicine
Ute Ströher
Ute Ströher Centers for Disease Control and Prevention

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